Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Descamps (1997)
Title Susceptibility of human immunodeficiency virus type 1 group O isolates to antiretroviral agents: In vitro phenotypic and genotypic analyses.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup O
SelectedType Clinical
NumIsolates 10
NumPts 10
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
BCF-01 BCF01 None None  A98G, V179E, Y181C E6A, T7P, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, S68G, D86E, K102Q, K103R, K104Q, V118C, K122P, I135V, E169D, Q174N, D177E, I178L, E194P, I195L, G196T, Q197E, T200K, K201R, I202V, Q207E, L210Y, R211Q, V245Q, E248N, S251V, V261I D121G, E204M 
BCF-02 BCF02 None None  A98G, V106I, V179E, Y181C P4Q, E6A, T7P, V21I, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, T69N, R83K, K102Q, K104Q, V118C, K122P, D123G, I135V, E169D, K173R, Q174D, D177E, I178L, E194P, I195L, G196T, Q197E, T200K, K201R, I202V, Q207E, L210Y, R211Q, V245Q, E248S, S251V, V261I K126P, N136Y, E204L 
BCF-03 BCF03 None None  A98G, V179E, Y181C E6A, T7P, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, S68G, K102Q, K104Q, V118C, K122P, I135V, E169D, Q174D, D177E, I178L, E194P, I195L, G196T, Q197E, T200K, K201R, I202V, Q207E, L210Y, R211Q, L228Q, V245Q, E248N, S251V, V261I E204L 
BCF-06 BCF06 None None  A98G, V179E E6A, T7P, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, V60I, S68G, K102Q, K103R, K104Q, V118C, K122P, I135V, I142V, A158P, T165I, Q174N, D177E, E194P, I195M, G196T, Q197E, T200K, I202V, Q207E, L210Y, R211Q, P243T, V245Q, E248N, D250E, S251V N147I, E204L 
BCF-07 BCF07 None None  A98G, V106I, V179E, Y181C P4H, E6A, T7P, V21I, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, K102Q, K104Q, V118C, K122P, I135V, E169D, Q174N, D177E, I178L, E194P, I195L, G196T, Q197E, T200K, K201R, I202V, Q207E, L210Y, R211Q, V245Q, E248N, D250E, S251V, V261I K126P, E204L 
BCF-08 BCF08 None None  A98G, V179E, Y181C E6A, T7P, V21I, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, K102Q, K104Q, V118C, K122P, I135V, E169D, Q174S, D177E, I178V, E194P, I195L, Q197E, T200K, I202V, E204T, Q207E, L210Y, R211Q, L228Q, V245Q, E248N, S251V D185V, G196P 
BCF-11 BCF11 None None  A98G, V179E E6A, T27S, E28R, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, K102Q, K103R, K104Q, V118C, K122P, I135V, E169D, Q174D, D177E, E194P, I195L, G196T, Q197E, T200K, K201R, I202V, Q207E, L210Y, R211Q, D218N, V245Q, E248S, D250E, S251V E204L 
BCF-13 BCF13 AZT, 3TC None M184V A98G, V106I, Y181C E6A, T7P, V21I, T27S, E28K, K32E, V35T, E36A, T39Q, K43Q, K49R, V60I, K102Q, K103R, K104R, V118C, K122P, K126Q, I135V, T165I, E169D, Q174D, D177E, I178L, E194P, I195L, G196T, Q197E, T200K, K201R, I202V, Q207E, L210Y, V245Q, E248N, S251V, V261I N54D, V179K, E204L 
RUD RUD None None  A98G, V179E E6D, T7P, T27S, E28R, K32E, V35T, E36A, T39Q, K43Q, S48T, K49R, V60I, K102Q, K104Q, V118C, K122P, D123S, I135V, E169D, Q174N, D177E, E194P, I195L, Q197E, T200K, I202V, Q207E, L210Y, R211K, V245Q, E248N, D250E, S251V E204L 
VAU VAU None None  A98G, V179E E6T, T7P, T27S, E28R, K32E, V35T, T39K, K43Q, K49R, V60I, S68G, K101R, K102Q, K104Q, V118C, K122P, D123E, I135V, I142V, K166Q, E169D, Q174N, D177E, I178L, E194P, I195L, G196A, Q197E, T200K, K201R, I202V, Q207E, L210Y, R211K, V245Q, E248D, D250E, S251V E204L