Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Baxter (2006)
Title Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 3371
NumPts 3222
Subtype B, CRF12_BF, F, A, C, D, CRF02_AG, G, CRF04_cpx, CRF09_cpx, J, CRF45_cpx, CRF01_AE, K, CRF18_cpx, G + Unknown, CRF11_cpx, CRF17_BF, H, B + F, CRF06_cpx


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Page 1   listing Isolate 1 to Isolate 100 from Total 3371 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
12-1001 1001-30227 NRTI NNRTI M41L, D67G, T69DE, L74LV, L210W, T215Y, K219KR  E44D, V60I, S68SG, V118I, K122E, D123DE, S162A, D177E, I178M, T200S, Q207E, R211K  
12-1004 1004-30304 NRTI NNRTI M41L, D67N, T69D, M184V, L210W, T215Y, K219N K101H, V106I, Y181C, G190A, H221Y, F227L K43E, E44A, V118I, K122E, I135T, S162SC, G196E, Q197K, T200A, E203D, H208Y, R211K  
12-1006 1006-30310 NRTI NNRTI M41L, D67N, L210W, T215D  K43Q, E44D, V60I, V118I, K122E, S162Y, I178F, Q197K, T200A, Q207N, R211K, E224DN  
12-1007 1007-30519 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y F227L T39S, E44D, V111I, V118I, K122E, D123N, K173A, Q174K, D177E, I178L, T200A, E203K, Q207E, H208Y, R211K, K223E, V245Q  
12-1009 1009-30522 NRTI NNRTI M41L, D67N, T69D, L74LI, V75VIM, Q151M, T215Y, K219KE L100I, K103N, H221HY K122E, R172K, I178IM, T200A, E203D, Q207A, R211A, L228LR  
12-1024 1024-30319 NRTI NNRTI A62V, T69S_VA, T215Y A98G, K103N, Y181C, G190A K43Q, V118I, S162A, K173KR, Q207E, R211K, L228H, V245I  
  1024-30513 NRTI NNRTI M41L, D67N, L74I, M184V, L210W, T215Y, K219N K103N, V106I, G190A T39A, E44D, V75X, V118I, K122E, T200A, E203D, H208HY, R211RK, D218E, V245T  
12-1027 1027-30324 NRTI NNRTI K219KN Y181YC D121H, K122E, T139A, I142V, S162A, T200A, R211RQ  
12-1044 1044-30603 NRTI NNRTI  K103N D123E, S162C, Q207E, R211K  
12-1093 1093-30224 NRTI NNRTI D67N, M184V, T215CY, K219E  V118I, K122E, D123E, G196GE, T200I, R211K  
12-1099 1099-30303 NRTI NNRTI M184MIV  A98S, K102KR, T165I, E194ED, I202V, R211K  
12-1103 1103-30610 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y K103DN V118I, K122E, A158S, S162C, R211K, V245K  
12-1111 1111-30410 NRTI NNRTI M41L, D67N, T69D, V75M, M184V, L210W, T215Y  T39TA, E40F, K43E, V60I, A98S, V118I, K122E, I135T, I142V, G196E, E203K, Q207E, H208HY, R211K, K223KQ  
12-1119 1119-30318 NRTI NNRTI M41L, T215F K103N V118I, K122E, D123N, I135T, Q197LP, F214L, L228R, K238KR, V245K  
12-1120 1120-30319 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y  T39A, K43E, E44A, V118I, K122E, T139M, G196E, H208Y, R211K, W212M  
12-1127 1127-30310 NRTI NNRTI M184MV K103N S68G, T69A, V118VI, I135T, T200I, Q207E, R211K  
12-1129 1129-30311 NRTI NNRTI M41L, D67N, L210W, T215CY, K219N  T39E, E44D, V118I, K122E, I135T, I142V, S162C, E169D, V179I, V189VI, T200A, I202V, H208HY, R211K, V245E  
12-1132 1132-30320 NRTI NNRTI M41L, M184V, T215F A98G K122E, D123N, H208HY, R211K, V245E  
12-1134 1134-30326 NRTI NNRTI M41L, L210W, T215Y  K43E, S68G, V75L, K102Q, V118I, K122E, T200TI, H208HY, R211RK  
12-1143 1143-30403 NRTI NNRTI M41L, D67DN, L210W, T215Y, K219R K103KN, V108VI, H221Y E44D, A98S, V118VI, K122E, G196GE, H208HY, R211D, V245M  
12-1145 1145-30318 NRTI NNRTI M41L, D67N, T69D, M184V, L210W, T215Y K103N, Y181YC T39A, K43E, E44D, W88WC, A98S, V118I, K122E, T200TA, E203D, Q207T, H208Y, R211K, L228H  
  1145-30401 NRTI NNRTI M41L, D67N, T69D, M184V, L210W, T215Y K103N, Y181YC T39A, K43E, E44D, W88WC, A98S, V118I, K122E, T200A, E203D, Q207T, H208Y, R211K, L228H  
12-1150 1150-30408 NRTI NNRTI M41L, L74V, M184V, L210W, T215Y K101E, Y181C, G190A K122E, I135T, T200S, R211K, K223KE, L228LR  
12-1278 1278-30417 NRTI NNRTI L74V, M184V K101E, G190A, P225H D123E, S162C, D177E, I178M, V179VI, T200A, Q207E, R211K  
12-1281 1281-30424 NRTI NNRTI M41L, D67N, L210W, T215Y, K219R K103N, E138Q T39A, V60I, T69TN, K122E, I135M, Q174K, N175Y, G196E, R211K, V245VE L120L*W, V189VL, K201IV 
12-1283 1283-30220 NRTI NNRTI M41L, D67N, L74V, M184V, L210W, T215Y Y181C T39A, K64KR, K122E, D123N, I135R, I202V, E224D  
12-1313 1313-30513 NRTI NNRTI M41L, D67N, T69D, V75M, L210W, T215Y, K219N L100I, K103N E44ED, V60I, K64KR, V90VI, V118I, K122E, I135T, K173E, E203ED, R211K, K223T, L228R  
12-1321 1321-30402 NRTI NNRTI M41L, L74V, L210W, T215Y Y188L T39TA, K43E, E44D, E53EK, S68G, K82R, V118I, K122E, I135T, T139K, S162A, R172K, R211K, K223T, E224D  
12-1326 1326-30701 NRTI NNRTI M41L, D67N, K70R, L74V, T215S, K219Q L100I, K103N V60I, T69N, K122E, I135T, D177E, G196E, Q207E  
12-1337 1337-30414 NRTI NNRTI M41L, M184V, L210W, T215Y, K219R K103KN K122E, I135L, S162Y, T200A, L228H, V245K  
12-1345 1345-30501 NRTI NNRTI M41L, D67N, T69D, L74V, L210W, T215Y, K219Q A98G, K103N, V106VI, Y181C, G190A T39A, E40F, K122E, D123N, G196E, E203K, Q207E, H208Y, K223E, L228H K65K_N 
12-1350 1350-30624 NRTI NNRTI D67N, K70R, M184MI, T215F, K219E A98G, Y181C S48T, K122E, D123E, S162A, K173N, D177E, T200A, I202V  
12-1359 1359-30729 NRTI NNRTI L210LW, T215TS, K219KN L100LI, K103KN, E138A T39TA, K43KE, V60I, R83RK, W88WC, I135IV, I202IV, R211K, V245EK  
12-1365 1365-30728 NRTI NNRTI M41L, D67G, L74I, M184V, L210W, T215Y, K219N K103N K43Q, E44D, S68G, V118I, K122E, I135T, S162C, I202V, D218E, V245E  
12-1366 1366-30821 NRTI NNRTI M41L, D67HN, K70R, M184V, T215F, K219Q  T39A, K43E, V60I, S68SN, T69TN, I135V, S162Y, D177G, V179I, T200A, Q207A, H208Y, R211K, K223Q, L228H, V245Q  
12-1380 1380-30422 NRTI NNRTI D67N, K70R, M184V, K219Q A98G, K103N T39A, V60I, K173T, Q207E, F214L, V245K  
12-1417 1417-30729 NRTI NNRTI M41L, D67N, T69D, V75M, L210W, T215Y L100I, K103N T39I, V60I, V118I, D121Y, K122E, I135V, D177E, I178M, G196E, E203D, Q207E, R211K, K238R K126KE 
12-1421 1421-30331 NRTI NNRTI A62AV, K65R, K70R, V75VI, F116Y, Q151M, K219E K103N, Y181C S68G, D123E, S162C, K166Q, R172K, I178L, E204Q, Q207A, R211K, F214L, L228H  
12-1424 1424-30401 NRTI NNRTI M41L, D67N, L210W, T215Y A98G, K101H, K103H, Y181C, G190A, H221Y E40F, K43Q, K70X, I135T, R172K, D177E, G196GE, H208Y, R211K  
12-1428 1428-30313 NRTI NNRTI K65KE, D67N, K70R, T215I, K219E Y181V T69N, K122E, S162A, Q207E, R211K, L228HR, P243S, V245E  
12-1437 1437-30731 NRTI NNRTI D67N, T215Y V179VD K103R, Q207E, R211K, P243T, V245T  
12-1623 1623-30320 NRTI NNRTI A62V, T69G, K70KR, M184V, T215F, K219E A98G D67X, I135R, S162C, Q174QK, V179I, G196E, T200A, H208HY, V245E  
12-1626 1626-30328 NRTI NNRTI K65R, D67N, K219E Y181C K43Q, K103R, K122E, Q174R, T200A, Q207E, V245E  
12-1645 1645-30313 NRTI NNRTI M41L, M184V, L210W, T215Y, K219N Y181C, G190A, F227FL T39TK, K43E, E44AD, K101X, V111I, V118I, T165TI, E203K, Q207QE, H208Y, R211K, K223Q, L228R  
12-1669 1669-30319 NRTI NNRTI M41L, D67DN, L210W, T215Y A98G, K103N, Y181C T39A, E40F, K43E, E79D, K82R, R83K, K122P, I178L, I195IK, E203K, H208Y, R211K, K223E, L228R  
12-1670 1670-30319 NRTI NNRTI M41L, A62V, D67N, V75I, M184V, L210W, T215Y, K219N K103N, Y181C, G190A E44D, V118I, K122E, I135T, I142V, D177E, G196E, H208Y, R211K, L228H, Q242L  
12-1676 1676-30331 NRTI NNRTI M41L, D67N, L74V, M184MV, L210W, T215Y, K219N Y181C, G190A E44D, V118I, K122E, I135T, V179I, T200A, D218E, V245K  
12-1696 1696-30429 NRTI NNRTI A62V, L210W, T215Y  V118I, K122E, R172RK, D177N, R211Q  
12-1712 1712-30410 NRTI NNRTI D67N, K70R, L74I, M184V, T215F, K219Q A98G, K103N, Y181C, H221Y V118I, D123E, I135T, T165I, Q182H, G196E, T200I, F214L  
12-1731 1731-30501 NRTI NNRTI   S48T, K122E, I178IM, T200I  
12-1741 1741-30515 NRTI NNRTI M41L, D67N, V75ILM, M184V, L210W, T215FY K103N, V106VA, V108VI, P225PH, K238KT T39K, K43E, E44D, K82KR, K101KR, K102KR, V118I, K122E, I135T, I142IT, I178L, V189I, G196EK, Q197E, E203D, H208Y, R211K, V245E  
12-1757 1757-30604 NRTI NNRTI M41L, D67N, T69D, K70R, M184V, T215F, K219Q K103N, V106VI, G190A, H221Y, F227L T39AS, E40ED, A98S, K102Q, I135V, K166R, I167V, G196E, I202IV, E203K, Q207E, H208Y, L228H, Q242H, V245M D186DY 
12-1803 1803-30515 NRTI NNRTI M41L, D67N, K70R, L74V, V75T, L210LW, T215F, K219E L100I, K103N, M230L T39A, K102R, P140PT, I142T, E169D, V179VI, G196GE, T200A, I202V, D218DE, L228H, Q242QH  
12-1809 1809-30429 NRTI NNRTI D67N, K70R, V75A, M184MIV, K219Q  V90VI, V118VI, K122E, D123E, S162Y, G196GR, T200A, E203K, Q207E, D218DE, V245E K64*Y, K73IM 
12-1841 1841-30728 NRTI NNRTI D67N, T69D, T215F Y181C, G190S, H221Y K43E, K101Q, K122E, K166R, T200A, E203D, Q207A, H208Y, R211K  
12-1870 1870-30811 NRTI NNRTI   K122E, T165TI, K166KI, T200I, R211K  
12-1877 1877-30602 NRTI NNRTI M41L, A62V, T69T_ST, V75I, L210W, T215Y  K64R, V118VI, K122E, D123E, I135V, D177E, G196E, R211K, V245M  
12-1888 1888-30625 NRTI NNRTI M41L, D67N, L74I, M184V, L210W, T215Y, K219N A98G, V108VI, Y181C, G190A K43E, E44A, K101N, V118I, I142V, G196E, T200I, H208Y, R211K  
12-1900 1900-30527 NRTI NNRTI M41L, D67N, L74LIV, M184V, L210W, T215Y, K219N A98G, K103N V118I, K122E, T200A, H208HY, R211Q D186DY 
12-1915 1915-30714 NRTI NNRTI M41L, D67N, K70R, L74I, V75T, M184V, T215F, K219Q V108I, Y181C, H221Y T69N, K101Q, D123E, V179VI, G196GE, T200I, I202V, Q207N, L210LF  
12-1926 1926-30519 NRTI NNRTI M41L, D67G, T69D, L74V, M184V, L210W, T215Y, K219R A98G, V108I, Y181C S68G, K101Q, K122E, D123DE, E203K, R211D, K223Q, L228H  
12-1927 1927-30527 NRTI NNRTI D67N, K70R, F77FL, F116Y, Q151M, M184V, K219Q K103N, E138A, Y188YH V60I, K122E, I135T, S162C, Q197E, F214L  
12-1928 1928-30818 NRTI NNRTI M184MV K103N R83K, K122P, I135T, D177E, T200IM, Q207A, R211RK  
12-1964 1964-30527 NRTI NNRTI M41L, L74V, M184V, L210W, T215Y K103N, V108I, Y181C K43N, V118VI, K122E, V179I, R211K, K223Q  
12-1970 1970-30604 NRTI NNRTI M41L, D67N, L74V, L210W, T215Y, K219N Y181C, G190A T39K, K43E, E44D, K101Q, K102Q, V118I, K122E, S134SG, I135T, S162C, E169D, E203D, H208Y, R211K, D218E  
12-1976 1976-30604 NRTI NNRTI M41L, D67N, T69D, L74V, M184V, L210W, T215Y L100I, K103N K43N, D123E, Q174R, E203K, Q207D, R211RK, L228H  
12-1979 1979-30514 NRTI NNRTI M41L, M184V, L210W, T215Y  T39S, R83RK, A98S, K122P, I142V, Q174QR, D177E, G196E, Q207E, R211K, L228R, D237E  
12-2002 2002-30610 NRTI NNRTI M41L, D67N, K70R, L74V, T215F, K219Q K103N, Y181C T69N, A98S, K122P, D177E, H208Y, D218E, L228H  
12-2005 2005-30630 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y, K219KR K101EQ, V106I, Y188L E44D, V118I, K122E, D123E, I135T, S162C, T200A, E203Q, Q207E, R211RK, V245E R206I 
12-2029 2029-30724 NRTI NNRTI D67NS, K70R, T215F, K219Q Y181C, G190A T39N, K46Q, T69N, K101A, K103R, K122E, I135V, K166R, Q207DN, D218E, L228H, P243PH, V245E  
12-2031 2031-30728 NRTI NNRTI M41L, D67N, K70R, M184V, L210W, T215Y, K219E K101E, Y181C T39A, E44D, V60I, I94L, I135T, T139R, Q174QR, G196E, I202IV, E203K, L228H  
12-2038 2038-30709 NRTI NNRTI M41L, D67G, K70T, V75M, M184I, L210W, T215Y, K219N Y181C, G190S T39A, E40F, K43KE, S68G, K101N, V118I, K122E, I135T, R211K, L228H, V245T  
12-2050 2050-30625 NRTI NNRTI M41L, D67N, K70R, T215F, K219Q A98G, Y188L, H221Y V60I, K102KM, K122E, S162ST, D177E, I202V, Q207K, H208Y, R211S, F214L  
12-2077 2077-30609 NRTI NNRTI M41L, D67N, L210W, T215Y, K219KR K103N, E138A, Y188L K43Q, E44D, S48T, V60I, A98S, V118I, K122E, I135MT, G196E, R211N, E224ED  
12-2098 2098-30613 NRTI NNRTI   D123E, T200TA, R211K  
12-2100 2100-30613 NRTI NNRTI M41L, D67G, K70R, L74I, M184V, T215Y, K219E  E44ED, S68G, V118VI, K122E, I178M, T200A, D218E, L228LH  
12-2127 2127-30729 NRTI NNRTI M41L, D67N, T69D, L210W, T215Y A98G, Y181C E44D, V118VI, K122E, I135T, G196E, T200A, I202V, H208HY, R211K, V245K  
12-2137 2137-30723 NRTI NNRTI M41L, D67N, K70R, T215Y, K219E K103N, V108I T39TA, S68G, K102Q, V118I, K122E, I135IT, I178IM, T200A, Q207E, R211K, L228H, V245K  
  2137-31022 NRTI NNRTI M41L, D67N, K70R, M184I, T215Y, K219E K103N, V108I, Y318F S68G, K102Q, V118I, K122E, I135T, I178IM, T200A, Q207E, R211K, L228H, V245K, I293V, S322ST, M357T, R358K, V365I, E399G  
  2137-40728 NRTI NNRTI M41L, D67N, K70R, L74LI, M184V, T215Y, K219E K103N, V108I, Y318F S68G, K102Q, V118I, K122E, T200A, Q207E, R211K, L228H, V245K, I293V, M357T, R358K, G359GS, V365I, T386I, E399G  
12-2160 2160-30702 NRTI NNRTI M41L, D67N, L74V, L210W, T215Y, K219N A98AG, Y181C E44D, K82R, K122E, I135V, T139V, S162C, E203K, H208Y, R211K, K223Q  
12-2168 2168-30804 NRTI NNRTI D67DN, M184V K103N E53D, K122E, I135V, S162C, I178M, Q197K, T215X, V245E  
12-2177 2177-30627 NRTI NNRTI M41L, D67G, T69D, K70R, L210W, T215Y K103N, Y181C K122KE, K173QR, V245I  
12-2183 2183-30701 NRTI NNRTI A62V, T69G_SG, T215Y K103KN, Y181C I135T, K166R, L228H  
12-2184 2184-30807 NRTI NNRTI M184V K103N, P225H I135IT, S162A, V179VI, I244V  
12-2195 2195-30630 NRTI NNRTI M41L, D67N, K70R, M184V, L210W, T215Y, K219DE K103N T39A, E44D, S48E, A98S, V118I, D123E, D177E, I178IM, T200A, E203V, Q207E, H208Y, R211K, L228H, V245E  
12-2231 2231-30715 NRTI NNRTI D67N, T69D, L74V, M184V, T215F, K219Q K101E, Y181C, G190S V60I, A98S, I135V, D218E, L228H, V245I  
12-2251 2251-30730 NRTI NNRTI  E138A S48T, D121DH, K122E, I135T, K173KR, I178IM, T200A, I244V  
12-2254 2254-30710 NRTI NNRTI D67G, K70R, L74LI, M184V, T215I, K219Q K103S, G190A, K238T K64H, T69N, V118I, K122E, I135T, G196E, Q197K, T200A, F214L, L228H, V245K  
12-2275 2275-30725 NRTI NNRTI M41L, D67N, K70R, V75T, T215Y, K219E K103N, Y181C K49R, K122E, D123N, I135V, S162C, E169D, P170L, L228H  
12-2395 2395-30728 NRTI NNRTI M41L, D67N, T69D, Q151M, T215Y, K219KE L100I, K103N, H221Y V90VI, K122E, R172K, I178IM, T200A, E203D, Q207A, R211A, L228LR  
  2395-30807 NRTI NNRTI M41L, K65R, D67T, T69D, Q151M, T215Y, K219KE L100I, K103N, H221Y E79D, K102KR, V111L, K122E, N137NI, R172K, I178IM, T200A, E203D, Q207A, R211A, L228LR  
12-2412 2412-30812 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y, K219KR  E44D, K102KR, V111I, V118I, K122E, I178L, T200A, E203D, Q207D, H208F, R211K  
  2412-31119 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y, K219R  P4Q, E28K, K32E, V35M, E44D, V111I, V118I, K122E, I178L, T200A, E203D, Q207D, H208F, R211K, A272P, K275R, K277R, T286A, E297K, D324E, G333E, Q334H, G335S, M357V, V365I, A371V, K390R, E399D, A400T  
12-2415 2415-30821 NRTI NNRTI M41L, D67N, T69D, K70R, L210W, T215Y, K219Q Y188L E44D, V118VI, K122E, R172K, D177E, I178M, T200TA, E203K, Q207E, R211K, K223Q, L228H  
12-4009 4009-30129 NRTI NNRTI M41L, D67N, L74V, M184V, L210W, T215Y A98G, K101H, V108I, Y181C, H221Y V118I, K122E, E203D, Q207K, H208Y, R211D, E224D  
12-4023 4023-30529 NRTI NNRTI M41L, D67N, L74I, V75T, L210LW, T215FY, K219N K103KN, V108I, Y181C, G190A, H221Y E44ED, K122E, D123E, I135V, N175H, D177E, G196E, T200A, K201I, E203D, E204Q, Q207QE, H208Y, R211K  
12-4070 4070-30226 NRTI NNRTI M41L, L74LV, M184V, L210W, T215Y K101P, V106VA, G190A E44D, V75VL, V118VI, K122E, V179VI, T200TA, Q207E, H208Y, R211K, D237DN  
12-4077 4077-30318 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y K103N T39A, E44D, A98S, V118I, K122E, I135T, Q197E, T200R, Q207K, R211D I63K 
12-4083 4083-30311 NRTI NNRTI K65KR, D67DN, T215TN G190S, K238KT R83K, D121Y, K122E, S162A, I178L, V179I, R211T