Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Bernardin (2005)
Title Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 18
NumPts 9
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
1001 1001-07 None None   I135T, Q197P, T200A, R211K, F214L, I293V, I326V, Q334L, K390R, A400S, R463K, S468P, T470A, Q509R, S519N, Q524E, Q547K, A554T  
  1001-09 None None   I135T, Q197P, T200A, R211K, F214L, I293V, I326V, Q334L, K390R, E396EG, A400S, R463K, S468P, T470A, Q509R, S519N, Q524E, Q547K, A554T  
1006 1006-08 None None   I135T, I142M, A158S, T165I, V179I, R211K, K277R, I293V, V317A, D324E, Q334L, A376T, T386I, T403L, N447S, G490E, Q509L, V559I  
  1006-10 None None   I135T, I142M, A158S, T165I, V179I, R211K, K277R, I293V, V317A, D324E, Q334L, A376T, T386I, T403L, N447S, G490E, Q509L, V559I  
1012 1012-08 None None   R83K, K122P, I135V, I159V, D177E, V179I, R211K, A272P, I293V, I329V, G333E, G335C, A371V, A376T, K390R, V435A, K454R, K465R, V531I, A554N  
  1012-11 None None   R83K, K122P, I135V, I159V, D177E, V179I, R211K, A272P, I293V, I329V, G333E, G335C, A371V, A376T, K390R, V435A, K454R, K465R, V531I, A554N  
1013 1013-03 None None   K20R, S162A, E248D, K281R, I293V, G333E, Q367L, K390R, E399D, A400T, V435M, V467I, A554T, I556V  
  1013-07 None None   K20R, K126KR, S162A, E248D, K281R, I293V, K311KR, G333E, Q367L, T369TI, K390R, E399D, A400T, V435M, V467VI, Q524QL, A554T, I556V  
1018 1018-06 None None   S48T, K122E, S162A, V245M, D250E, A272P, K277R, T286A, R358K, A360T, K366R, I375V, K390R, T403M, A446S, S468P, T470N, Q520L, Q524E, A554S  
  1018-10 None None   S48T, K122E, S162A, E233EK, V245M, E248EK, D250E, A272P, K277R, T286A, E308EK, R358K, A360T, K366R, I375V, K390R, T403M, A446S, S468P, T470N, H483HY, Q520L, Q524E, A554S  
1027 1027-05 None None   R83K, S162C, G196E, T200I, E203D, R211K, A272P, K277R, E297R, Q334L, M357V, K390R, A400I, K451R, D460N, H483N, L503I  
  1027-03 None None   R83K, S162C, G196E, T200I, E203D, R211K, A272P, K277R, E297R, Q334L, M357V, K390R, A400I, K451R, D460N, H483N, L503I  
1057 1057-01 None None   D123E, K201R, R211K, E224K, W252Y, K277R, T286A, E297K, A376T, T386I, K390R, A400I, V435I, A446S, D460N, H483Y, L491S, S519N, K527N  
  1057-09 None None   D123E, K201R, R211K, E224K, W252Y, K277R, T286A, E297K, A376T, T386I, K390R, A400I, V435I, A446S, D460N, H483Y, L491S, S519N, K527N  
1058 1058-08 None None M184V  V35A, T39A, R83K, K122R, D123E, I135V, D177E, R211K, S251T, K277R, Q278H, K390R, A400S, E404D, Q524E, A534T, Q547K  
  1058-11 None None M184V  V35A, T39A, R83K, K122R, D123E, I135V, D177E, R211K, S251T, K277R, Q278H, K390R, A400S, E404D, Q524E, A534T, Q547K  
PRB959 PRB959-03 None None   K122P, K173E, D177E, Q197H, Q207E, R211K, V245E, D250E, A272P, A288S, K311R, I329L, G333E, Q334Y, V365I, K390R, A400T, V435L, T470P, H483R, G490E, S519N, A554S  
  PRB959-05 None None   K122P, K173E, D177E, Q197H, Q207E, R211K, V245E, D250E, A272P, A288S, K311R, I329L, G333E, Q334Y, V365I, K390R, A400T, V435L, R463RG, T470P, H483R, G490E, S519N, A554S