Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sierra (2004)
Title The analysis of near full-length genome sequences of human immunodeficiency virus type 1 BF intersubtype recombinant viruses from Chile, Venezuela and Spain reveals their relationship to diverse lineages of recombinant viruses related to CRF12_BF.
Citation Infect Genet Evol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 6
NumPts 6
Subtype B, CRF44_BF

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CH12 CH12 None None   D123E, I159IL, F171FL, R172RK, E194EK, I195IR, R199RK, R211K, F214L, A272P, E291A, I293V, E297R, L301I, K311R, A376T, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452Q, S468P, D471E, K476KR, T477A, Q480H, H483Q, L491S, E492EK, T497TP, E516G, S519N, I526IM, K527E, K528KR, K530KR, A534S, V548I I482IF, Q500QH, V552VA 
CH3 CH3 Unknown, 3TC, D4T Unknown, NVP M41L, M184V, T215Y K103N K32R, V35I, V60I, K122E, I135L, T139R, Q197K, E248D, A272P, K281R, L283I, E297Q, M357T, K366R, A376T, A400T, V435I, R461K, L469I, T470D, H483L, L517I, S519N, A554S  
CH6 CH6 Unknown, AZT, 3TC Unknown   V35I, V60I, K122E, I135L, A272P, K281R, E297Q, M357T, I375V, A376T, A400T, V435I, R461K, L469I, T470N, H483L, L517I, S519N, A554T  
R140 R140 RTI RTI   D17G, T27A, V35I, R83K, S251D, A272P, K281R, T286A, E297K, S322T, M357T, A376T, A400T, V435I, D460N, R461K, T470N, H483L, S519N, K530KR, V548I, A554T  
V62 V62 RTI RTI   R83K, K122E, D123E, S162Y, V245M, A272P, E297R, L301I, V317A, A400T, V435I, D460N, R461K, H483Y, E516G, S519N, Q524E, A554T  
X1241 X1241 RTI RTI K219R  V35T, V60I, I135T, Q197K, T200E, Q207E, F214L, A272P, K281R, E297K, K311R, S322L, D324E, R358K, A376T, K390R, Q394L, E399D, A400T, T403S, K431T, V435A, G436E, A446S, L452A, D471E, T477A, Q480H, H483Q, L491S, S519N, K527N, A534S, A554S