Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Wilbe (2003)
Title Characterization of novel recombinant HIV-1 genomes using the branching index.
Citation Virology
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 6
NumPts 6
Subtype A, G, D

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
JKC-SE6954 VI6954 Unknown Unknown   K11Q, V35T, S48A, K49R, V60I, D121Y, K122E, D177E, I178M, T200I, Q207G, R211K, V245T, D250E, A272P, K277R, L282C, L283I, T286A, I293V, G335D, P345Q, F346Y, R356K, M357V, A360T, V365I, E370A, T377Q, S379C, K390R, A400T, E432D, I434M, S468P, D471E, Q480H, L491S, A534S, K540R, A554N, V559I  
JKC-SE8603 SE8603 Unknown Unknown  V108I K20R, V35I, K49R, V60I, K122E, D123S, I135T, K173S, Q174K, I178M, V179I, Q207A, R211S, P243S, V245K, D250E, A272P, T286A, E291D, I293V, P294T, E312D, G335E, R356K, M357K, G359S, T369A, A371V, I375V, A376V, T377M, T386A, A400T, T403M, E404D, E432D, V435I, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
SE8646 SE8646 Unknown Unknown   K20R, V35T, V60I, K122Q, K173T, Q174K, D177E, I178M, T200E, Q207E, R211K, D218E, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297A, F346Y, M357V, G359S, A371V, S379G, T386I, K390R, A400T, K431T, E432D, V435P, A446D, N447D, E449D, V466I, V467I, S468T, D471E, T477I, H483Q, G490E, L491S, N494H, K512R, S519N, L533I, A534T, A554S, K558R  
SE9010 SE9010 Unknown Unknown D67N, T69D, K70R, T215F, K219Q A98G E6D, K20R, V35T, V60I, L109I, K122E, D123S, K173T, D177E, G196E, T200A, I202V, Q207E, R211K, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297A, E300Q, Q334P, F346Y, M357V, R358K, G359S, T377S, S379G, K390R, A400T, K431T, V435P, F440Y, V467I, S468T, D471E, H483Q, L491S, K512R, E516D, S519N, K527Q, K530R, A534T, A554N K281KN 
UG035 UG035 None None   K11T, K20R, V21I, V35T, T39K, E53G, K122E, D123G, S162T, T165I, K173S, D177E, V179I, I202V, Q207A, V245Q, E248T, T253S, K259E, A272P, T286A, I293V, P294A, E312D, V317I, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377M, K395R, E396D, A400T, T403M, E404D, E413D, E432D, V435E, R461K, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527E, E529D, A534S, A554S, V559I P52L, A267P, Q428L 
UG266 UG266 None None   V35T, T39Q, K64R, K122E, D123S, T165P, K173S, N175H, T200P, K201Q, E204K, Q207A, R211S, V245Q, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, F346L, R356K, M357K, R358G, G359S, E370A, A371V, I375V, A376S, T386I, K390R, I393V, T403M, E432D, R461K, D471E, Q480H, H483Y, L491S, K512R, S519N, K527R, E529D, A534S, A554P W402C, A408P