Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Katzenstein (2000)
Title Virologic and CD4+ cell responses to new nucleoside regimens: switching to stavudine or adding lamivudine after prolonged zidovudine treatment of human immunodeficiency virus infection. ACTG 302 Study Team. AIDS Clinical Trials Group.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 6
NumPts 6
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ACTG302_1317 1317RT_bl AZT None K70R  E36D, T69N, D121Y, K122E, I135L, S162C, D177DE, I178IMV, V245MT, K277R  
ACTG302_1318 1318RT_bl AZT None K70R  K49KR, T69TS, R83K, D123E, I135T, S162CY, E169EA, I202V, L228LR, K277R  
ACTG302_194 194RT_bl AZT None   I142V, R211RG, N265NK  
ACTG302_2 2RT_bl AZT None K70R  A272P I274IM 
ACTG302_2465 2465RT_bl AZT None   R83K, I135T, L187LF, T215X I132IT, K223KN, Q258QH 
ACTG302_642 642RT_bl AZT None M41L, D67N, T69D, L210W, T215Y  K20R, V35M, K43X, E44ED, V60I, K104N, K122E, R211K, V245Q, K277RS