Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Ojesina (2006)
Title Subtype-specific patterns in HIV type 1 reverse transcriptase and protease in Oyo State, Nigeria: Implications for drug resistance and host response.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 35
NumPts 35
Subtype CRF02_AG, G, CRF06_cpx, A, D

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
AIO_DDJ013 AIO_DDJ013 None None   V21I, K32R, V35T, E36G, V60I, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, A355T, R356K, M357K, G359S, A371V, V372I, I375V, V381I, K390R, T403M, E432D  
AIO_DDJ025 AIO_DDJ025 None None   K20R, V35M, V60I, S68G, K102E, I135V, S162A, K173T, Q174A, D177E, I178M, T200A, Q207N, R211K, F214L, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, S322T, I326V, I329V, G335N, Q343H, N348D, R356K, M357R, G359S, T369V, A371V, A376S, K390R, E432D, V435A, A437V M16R, C38W, L210Q 
AIO_DDJ026 AIO_DDJ026 None None M41L H221Y K22N, I31V, V35T, T39R, E40D, K49E, V60I, V118I, K122E, D123N, T165I, K173T, Q174K, D177E, I178V, T200A, Q207E, R211A, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, Q334E, G335D, F346H, R358K, G359S, E370D, I375V, T377L, K390R, A400T, K431T, V435G L80F 
AIO_DDJ068 AIO_DDJ068 None None   T27P, V35P, T39A, D121Y, K122E, I135V, G141R, K173T, Q174K, D177E, I178L, I180V, T200A, Q207E, R211K, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, G359S, V365I, A371V, I375V, T377L, K390R, T403M, E432D, V435I E29Q 
AIO_DDJ071 AIO_DDJ071 None None   V35T, E36D, D121H, K122E, K154R, S162A, K173T, Q174K, P176S, D177E, I178M, T200A, Q207E, R211K, V245Q, D250E, S251T, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, T369A, A371V, I375A, A376T, S379C, A400T, T403M, E415V, E432D, V435L  
AIO_DDJ072 AIO_DDJ072 None None   V35T, K122E, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E, S251D, K281R, T286A, V292I, I293V, P294T, K311N, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, T403M, E413D, E432D, V435I  
AIO_DDJ075 AIO_DDJ075 None None   K22R, V35T, E36D, K122E, D123E, I135V, T139I, S162A, K173I, Q174K, N175Y, D177E, T200A, Q207E, F214L, V245Q, S251H, K275R, V276I, K281R, R284K, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, D364N, A371V, I375V, V381I, K390R, K395R, T403M, E413D, V435I  
AIO_DDJ077 AIO_DDJ077 None None  Y318F T7S, V35T, E36D, T39M, N57D, K122P, I135T, K173V, Q174E, D177E, I178L, T200A, Q207K, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, G335D, F346Y, R356K, M357K, G359S, K374R, T377M, T386I, K390R, E396D, A400T, K431T, A437V I180T 
AIO_DDJ078 AIO_DDJ078 None None   K11Q, V35T, E36D, V60I, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245K, D250E, K281R, T286A, E291D, V292I, I293V, E308V, S322T, G335D, W337R, R356K, M357K, G359S, A400T, T403M, E432D R78G 
AIO_DDJ102 AIO_DDJ102 None None   T7S, V35T, S162A, K173V, Q174K, D177E, I178L, T200A, Q207E, P243S, V245Q, K277R, T286A, E291D, V292I, I293V, S322A, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376S, I380V, T386I, K390R, K395R, A400T, T403M, E432D, V435A  
AIO_DDJ118 AIO_DDJ118 None None   E28A, V35T, V60I, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, V245R, A272P, K281R, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, V381I, K390R, T403M D121V 
AIO_DDJ125 AIO_DDJ125 None None M41L  K11T, V35T, E36D, T39A, S48T, A158S, S162A, T165V, K173I, Q174K, D177E, T200A, Q207E, V245E, S251N, V276T, T286A, E291D, V292I, I293V, P294T, V317A, S322T, I326V, R356K, M357K, G359S, A371V, I375A, K390R, T403M, E432D, A437V  
AIO_DDJ128 AIO_DDJ128 None None   K20R, V35T, V60I, K102R, K173A, Q174R, D177E, I178M, T200V, Q207D, R211K, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, D324E, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, T377L, V381I, T386V, K390R, Q394R, A400V, E413D, K431T, V435A, F440Y H208Q 
AIO_DDJ133 AIO_DDJ133 None None   K22N, V90I, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, V245K, D250E, A272T, T286A, E291D, V292I, I293V, P294T, E297K, S322T, G335D, R356K, M357R, G359S, T369A, A371V, I375A, I380V, V381I, T386P, K390R, T403M, E432D, V435E  
AIO_DDJ134 AIO_DDJ134 None None  Y188H V35T, E36D, E40D, K49R, V60I, K122E, A158S, D177E, I178M, T200I, Q207G, R211K, V245K, D250E, A272P, K275R, Q278H, L282C, L283I, I293V, A327V, G335D, P345Q, F346Y, R356K, A360T, T377Q, K390R, A400T, A408V, E432D  
AIO_DDJ135 AIO_DDJ135 None None   V35T, V60I, R78K, D123N, I135V, I142V, Q174R, D177E, I178M, T200A, Q207D, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, D324E, I329V, Q334L, G335D, F346Y, R356K, M357K, R358G, G359S, K366R, T377I, T386I, Q394R, A400V, E413D, Q428R, K431T, V435P, F440Y  
AIO_DDJ137 AIO_DDJ137 None None   V35T, T39M, V60I, K122E, D123S, I135T, K173T, Q174N, D177E, I195T, T200A, Q207E, V245R, E248D, D250E, A272P, T286A, E291D, I293V, P294T, I329V, Q334R, G335D, F346Y, R356K, M357R, R358G, G359S, S379G, V381I, T386V, Q394R, E399D, A400V, K431T, V435L, F440Y  
AIO_DDJ140 AIO_DDJ140 None None   K32N, V35T, E36D, E40G, K49R, V60I, K122E, D123S, I135T, S162A, F171Y, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, H235N, V245Q, E248D, D250E, A272P, K277R, C280S, T286A, E291D, V292I, I293V, K311R, D324E, I329V, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, T386V, Q394R, A400V, E404D, E413D, K431T, V435P, F440Y Q269L 
AIO_DDJ150 AIO_DDJ150 None None   V35T, E36D, V60I, I135V, S162A, P170S, K173A, Q174K, D177E, T200E, Q207E, P236L, V245Q, E248D, S251C, K277R, T286A, E291D, V292I, I293V, S322T, D324E, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K390R, A400T, T403M, K431R, E432D, V435A V111E, N147D 
AIO_DDJ164 AIO_DDJ164 None None   V35T, I135V, S162A, K173A, Q174R, D177E, T200A, Q207K, R211S, V245Q, V276I, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357R, G359S, A371V, K390R, E399D, T403M, V417I, V423A, E432D, V435A, G436E R143G 
AIO_DDJ166 AIO_DDJ166 None None   E6K, K11A, V35T, K122E, I142V, T165P, K173T, D177E, V189A, T200A, Q207A, R211S, E248N, K275Q, K277R, T286A, E291D, I293V, E297K, D324N, G335D, R356K, M357R, G359S, A371V, I375V, A376T, A400T, T403M, E432D  
AIO_DDJ168 AIO_DDJ168 None None   V35T, T39K, E40D, V60I, D121H, K122E, I135T, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245R, E248D, D250E, A272P, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, A376T, V381I, T386I, Q394R, A400V, K431T, V435A, F440Y I2M, K287E 
AIO_DDJ171 AIO_DDJ171 None None   V35T, D123E, I135V, S162A, E169Q, K173A, Q174E, D177E, T200A, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, E297D, G316R, S322A, G335D, R356K, M357R, G359S, H361R, T369A, E370D, A371I, I375V, A376T, T377V, K390R, K395R, A400T, T403M, E413D, V435M  
AIO_DDJ172 AIO_DDJ172 None None   K20R, I31V, V35T, T39K, K46R, V60I, D121Y, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, S251V, A272P, I274V, Q278H, K281R, T286A, E291D, V292I, P294T, E297T, L301M, I329V, Q334P, G335D, F346Y, Y354F, R356K, M357R, R358G, G359S, A371V, S379G, T386I, Q394R, A400V, K431T, V435L, F440Y G231R 
AIO_DDJ174 AIO_DDJ174 None None   V35T, T39M, S48T, I135V, A158S, S162A, F171Y, K173A, Q174K, D177E, I178V, Q207E, V245E, E248D, K281R, T286A, V292I, I293V, P294T, E297K, V317A, S322T, D324E, I326V, R356K, M357K, G359S, T369A, A371V, I375A, K390R, T403M, E432D  
AIO_DDJ177 AIO_DDJ177 None None   K20R, V35T, E36D, S48T, V60I, K122E, D123E, I135V, S162A, K173A, Q174K, I178L, T200A, Q207E, R211K, T286A, E291D, V292I, I293V, P294T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, V381I, K390R, T403M, E432D, V435I  
AIO_DDJ179 AIO_DDJ179 None None   V35T, T39A, V60I, W88C, K104R, K122E, D123S, I135R, F171Y, K173T, Q174K, D177E, T200A, I202V, Q207E, F214L, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E302G, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V365I, T386V, K390R, Q394R, A400V, E413D, K431T, V435S, F440Y  
AIO_DDJ190 AIO_DDJ190 None None T215A  K20R, V35T, T39N, E40D, V60I, D121H, K122E, D123S, K173T, Q174K, D177E, T200A, Q207D, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, P294T, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359P, V381I, T386V, Q394R, A400V, E413D, Q428R, K431T, V435L, F440Y  
AIO_DDJ192 AIO_DDJ192 None None   V35T, V60I, K104R, K122E, K173T, Q174K, D177E, Q197P, T200A, Q207E, R211K, V245E, T286A, E291D, V292I, I293V, P294T, V317A, S322T, K323R, G335D, R356K, M357K, G359S, A371V, I375V, K390R, E399D, T403M, E432D V254A 
AIO_DDJ262 AIO_DDJ262 None None M41L V179E V35T, T39A, V60I, D121H, K122E, I135R, K173R, Q174E, D177E, I178V, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, F346Y, M357I, R358K, G359S, K366R, T377L, K390R, K431T H96Y 
AIO_DDJ267 AIO_DDJ267 None None   V35I, K49R, I50V, K104E, D123E, I135L, S162A, K173T, Q174E, D177E, T200A, E204K, Q207D, V245Q, K277R, T286A, V292I, I293V, E297K, V317A, S322T, G335D, R356K, M357K, G359S, A371V, I375A, T377L, K385R, K390R, K395R, T403M, E432D  
AIO_DDJ270 AIO_DDJ270 None None   V21I, K32R, V35T, V60I, K122E, D123N, S162A, D177E, T200V, Q207E, R211K, V245Q, E248N, A272P, V276I, T286A, E291D, I293V, E297A, Q334H, F346H, M357I, R358K, G359S, A376S, T377L, S379C, K390R, I393T, A400I, T403M, K431A  
AIO_DDJ274 AIO_DDJ274 None None   V10A, K20R, V35T, K122E, D123G, I135V, S162A, E169D, K173A, Q174E, T200A, Q207E, F214L, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357K, G359P, A371V, K390R, A400T, T403L, E432D, V435I I132M 
AIO_DDJ277 AIO_DDJ277 None None   V35T, E36D, V60I, K102R, K122E, D123N, K173A, Q174K, D177E, T200A, K201R, Q207G, R211K, V245Q, E248N, D250E, S251I, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376S, K390R, T403M, E432D  
AIO_DDJ278 AIO_DDJ278 None None   K20R, V35T, T39K, S48T, V60I, K102R, K122E, D123S, K166R, K173T, Q174R, D177E, T200E, Q207G, R211K, V245Q, E248D, D250E, S251T, A272P, I274V, K277R, Q278H, T286A, E291D, V292I, I293V, E297P, L301M, Q334L, G335E, F346Y, R356K, M357R, R358G, G359S, E370D, A371V, I375V, T386I, K390R, Q394R, A400V, E404D, K431T, V435L, F440Y