Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Vidal (2006)
Title HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC).
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 70
NumPts 70
Subtype A, C, D, G, F, CRF05_DF, J, CRF45_cpx, H, CRF02_AG, CRF11_cpx, G + J, CRF18_cpx, A + J, CRF25_cpx, G + H + J, CRF06_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
NV_KBS154 02.KBS154 None None   V35T, T39L, I135V, S162C, K173I, Q174K, T200A, Q207K, R211A, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297A, Q334E, R356K, M357T, G359S, T377L, Q394L, E399D, A400T, E404D, K431T, V435A  
NV_KBS187 02.KBS187 None None   E6D, K11R, V35T, T39K, K43E, K122E, D123N, I135T, I142V, K173A, Q174K, D177E, T200A, Q207A, R211S, F214L, V245Q, K249Q, T286A, E291D, V292I, I293V, E297R, A304E, E312N, G335D, R356K, M357R, R358K, G359S, A360T, V365I, T377M, K390R, A400T, E404D, V435A  
NV_KIST040 02.KIST040 None None   K11Q, V35T, V60I, K102Q, K122Q, D123G, I135V, S162C, K173A, Q174K, D177E, Q207E, V245Q, E248D, D250E, A272S, L283I, V292I, I293V, E297A, P321S, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, G359S, K390R, T397I, A400T, K431T, V435A  
NV_KIST061 02.KIST061 None None   P4H, K11T, V35T, T39K, K122E, D123N, I135V, K173I, Q174K, D177E, I178V, T200A, Q207A, R211S, F214L, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, A355T, R356G, M357K, R358G, G359S, T369A, E370A, I375V, I380V, K390R, K395R, A400T, T403M, E432D  
NV_KIST103 02.KIST103 None None   M16L, K20R, V35T, K49R, V60I, V118I, D121C, K122E, E169D, D177E, I178L, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, V292I, I293V, E297Q, I329L, G333E, Q334Y, M357R, K390R, V435I  
NV_KIST121 02.KIST121 None None   I5V, E6D, V35T, K49R, D121Y, K122E, T139A, K173T, D177E, T200E, I202V, Q207S, R211K, F214L, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297A, L301F, D324E, I329V, Q334L, G335D, R356K, M357R, G359T, K366R, T369A, A371V, I375V, T377L, K390R, K395R, A400T, E404D  
NV_KIST132 02.KIST132 None None   V35T, T39I, E40D, K49R, K122E, T165I, D177E, T200A, Q207E, P243S, V245Q, D250E, A272P, K311R, Q334H, M357T, A376T, K385R, K390R, A400T, T403I, V435I  
NV_KP009 02.KP009 None None   V35T, K49R, V60I, D121H, K122E, T139K, A158S, S162A, D177E, I178M, T200A, Q207A, R211K, V245Q, L246I, E248D, D250E, I257V, A272P, T286A, E291Q, I293V, P294E, E297K, S322A, Q334H, G335D, R356K, M357R, R358G, G359A, K366R, T369A, I375V, W383F, T386I, Q394R, A400I, E404D, Q428R, K431T, V435P, A437V, F440Y  
NV_KP061 02.KP061 None None   K20R, V35T, P55S, V60I, K122E, K173I, Q174K, D177E, T200A, Q207E, V245Q, E248N, D250E, A272P, Q278N, T286A, E291D, V292I, I293V, E297A, P345Q, F346Y, M357I, R358K, G359S, I375V, T377Q, K390R, A400T, K431T, A437V, F440Y A267T 
NV_KP063 02.KP063 None None  H221Y K20R, V35T, K49R, V60I, D121Y, K122E, I135T, T139V, S162C, E169K, D177E, Q207A, R211K, F214L, V245L, D250E, A272P, K277R, I329L, A360T, K366R, I375V, T377Q, S379C, T386M, K390R, E399D, T403I, E404D, V435M, F440Y  
NV_KP097 02.KP097 None None   E6K, K20R, V35T, V60I, D121Y, K122E, K173A, Q174K, D177E, Q207E, R211K, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, E297A, Q334H, G335D, Y342F, P345Q, F346Y, M357R, K366R, A371V, I375V, T377L, V381I, K390R, T403I, E404D, K431T  
NV_KP122 02.KP122 None None   V35T, K49R, K122E, I135V, K173T, Q174K, T200A, Q207A, R211K, V245Q, E248D, D250E, A272S, K281R, E291D, V292I, I293V, E297A, I326T, I329V, Q334H, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T386L, K390R, Q394R, E396D, A400V, E413D, Q428R, K431T, V435P  
NV_KP149 02.KP149 None None  E138A V35T, K49R, V60I, D123E, Q207A, R211K, V245Q, E248N, A272P, K281R, I293V, P294Q, P313T, M357A, T369A, T377L, S379G, K390R, A400T  
NV_KP152 02.KP152 None None   V35T, V60I, T107S, K122E, I135R, T139M, I178M, G196E, T200A, Q207D, R211K, I244V, V245K, A272P, T286A, A288T, E291D, V292I, I293V, E297K, G335D, F346S, R356K, M357L, G359S, V381I, T386I, K390R, A400I, Y405X, W410G  
NV_KP166 02.KP166 None None   K11T, V35T, T39M, E40K, V60I, T107S, K122E, D123G, D177E, T200A, Q207D, R211K, I244V, V245K, A272P, K277R, T286A, E291D, V292I, I293V, E297K, K311R, Y319X, Q334A, G335D, R356K, G359A, I375V, T386I, K390R, A400T, K431T, V435X P421Q 
NV_KP180 02.KP180 None None   E6D, K11T, V35T, K122E, D123G, K173A, Q174K, D177E, Q207T, R211S, F214L, V245K, A272P, T286A, V292I, I326V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T386P, K390R, K395R, A400T, W410C  
NV_KS009 02.KS009 None None   V35T, E40D, K49R, K122E, D123N, I142V, K173A, D177E, V179I, T200A, Q207A, R211S, V245Q, A272S, T286A, E291D, V292I, I293V, P294T, E312N, G335D, M357R, R358G, G359S, E370A, A371V, I375V, A376V, T403M, E432D, V435I  
NV_KS017 02.KS017 None None   V35T, E40D, K49R, K122E, D123N, S162C, K173A, Q174K, D177E, I178M, G196E, T200A, Q207E, R211K, L228M, V245Q, E248N, A272P, K311R, Q334H, G335E, M357S, A360T, S379G, K390R, A400T, E432D, V435A  
NV_KS018 02.KS018 None None   V35T, V60I, K104R, K122E, D123G, K173T, D177E, T200E, Q207E, R211K, V245Q, E248D, D250E, S251D, A272P, K277R, Q278H, E291D, V292I, I293V, T296S, E297A, Q334H, F346Y, M357I, R358K, G359A, T369S, T377R, K390R, A400T, E404D  
NV_KS033 02.KS033 None None   K20R, V35T, V60I, K122P, D123G, I135V, K173T, Q174K, D177E, I178L, T200A, E204K, Q207E, R211K, F214L, V245Q, E248D, A272S, T286A, E291D, V292I, I293V, E297T, K311R, E312N, I326V, Q334H, G335D, K350R, R356K, M357R, R358K, G359S, T369V, A371V, K374Q, I375V, E378Q, A400T, E404D, Y405H, P421H, K431A  
NV_KS035 02.KS035 None None   V35T, T39K, K122E, D123N, K173L, Q174K, D177E, T200A, Q207A, R211E, V245Q, A272P, K275R, K277R, Q278H, T286A, V292I, I293V, P294T, I326V, G335D, R356K, M357Q, G359S, T369A, I375V, K395R, A400T, E432D, V435X  
NV_KS049 02.KS049 None None   E6D, V35T, T39S, D121H, K122E, I142V, K173A, Q174R, D177E, T200E, I202V, Q207E, P243T, V245Q, E248D, D250E, A272P, K275Q, K277R, E291D, V292I, I293V, E297A, S322T, I329V, Q334L, G335D, R356K, M357R, G359T, K366R, A371V, T377M, K390R, K395R, A400T, E404D, V435A  
NV_KS069 02.KS069 None None   K20R, V35T, T39K, E40D, V60I, D121H, K122E, D123G, I142V, T165I, K173S, I178M, G196E, Q207A, V245E, D250E, S251I, A272P, T286A, E291D, V292I, I293V, P294T, T296S, E297K, E312D, M357R, G359S, A371V, I375V, A376V, K390R, E399D, A400T, T403M, V435M  
NV_KS072 02.KS072 None None   V35T, T39K, K43A, V60I, D123E, I135V, K173L, Q174K, D177E, Q197E, T200I, Q207D, R211K, V245Q, E248D, S251N, K281R, T286A, E291D, V292I, I293V, E297R, E312D, R356K, M357R, R358K, G359S, E370D, A371V, I375V, A376V, T377M, E399D, T403M, K431T  
NV_KS075 02.KS075 None None   V35T, T39A, E40D, V60I, K122E, D123E, I142T, D177E, I178L, G196E, T200I, Q207E, R211K, F214L, V245K, D250E, A272P, K323Q, Q334N, G335S, R356K, M357V, T369A, A376C, T377L, T386I, K390R, A400T, T403V  
NV_KS108 02.KS108 None None   E6D, V35T, V60I, T107S, K122E, D123S, I135V, S162A, K173A, D177E, T200A, Q207E, R211K, I244V, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, E297A, E312N, G335D, F346H, R356K, M357R, R358G, G359S, K390R, A400T, E404D, E413D, E432D, F440Y  
NV_KSFE110 02.KSFE110 None None   V35T, K49R, V60I, D121E, K122E, D123S, I135T, K173S, D177E, V179I, T200A, Q207A, R211S, V245L, D250E, S251I, A272P, T286A, E291D, V292I, P294T, E297K, E312D, G335D, M357R, G359S, T369A, A371V, I375V, A376V, T377L, K390R, A400T, T403M, E404D, E432D, V435I  
NV_KSFE141 02.KSFE141 None None   K22R, V35T, K49R, V60I, K122E, A158T, Q207E, R211K, V245E, D250E, A272P, T286A, I293V, Q334H, M357A, T369A, A376V, T386A, K390R, K395R, A400T, V435I, E438D  
NV_KSS004 02.KSS004 None None   V35T, T39N, E53D, D121H, K122E, I142V, A158S, K173I, Q174K, D177E, T200A, Q207E, R211K, V245K, K275Q, V276I, K281R, T286A, E291D, V292I, I293V, P294T, E297K, A304E, E312D, D324E, G335D, R356K, M357R, R358K, G359A, A360T, T377M, K390R, V435A  
NV_KSS006 02.KSS006 None None   P4T, T7P, K11Q, V35T, K49R, V60I, D121Y, K122E, D123E, E169Q, K173D, D177E, E204Q, Q207E, R211K, F214L, I244V, V245T, E248N, D250E, S251D, A272P, I293V, G335D, R356K, M357R, G359S, V365I, T377Q, K390R, E399D, V435A  
NV_KSS013 02.KSS013 None None   I5V, K11H, K20R, V35T, T39M, V60I, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, E248D, D250E, T286A, E291D, I293V, P294T, L295M, E312D, G335D, M357K, G359S, T369A, A371V, A376V, T377L, K390R, E399D, A400T, T403M, E404D, E432D  
NV_KSS023 02.KSS023 None None   K32R, V35T, E40D, V60I, K122P, I135V, S162C, K173T, Q174K, D177E, G196E, Q207E, P243S, I244V, V245K, D250E, A272P, K275R, Q278N, T286A, E291D, V292I, I293V, E297R, K311E, G335D, R356K, M357R, G359A, V365I, T377I, K390R, A400T, V435X  
NV_KSS055 02.KSS055 None None   V35T, E36A, T39E, S48T, D123E, T139A, A158S, K173T, D177E, T200A, Q207E, K238R, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294T, Q334N, G335D, R356K, M357R, G359T, T377Q, K388R, K390R, E404D  
NV_KSTB007 02.KSTB007 None None   P4S, E6D, V35T, T39M, V60I, I135V, I142V, K173A, D177E, T200K, Q207E, R211K, V245Q, E248D, D250E, S251A, A272P, V276I, R284K, T286A, E291D, V292I, I293V, E297T, D324E, L325I, I329L, F346Y, R356K, M357G, R358G, G359S, V365I, V372I, S379C, Q394R, A400I, E404D, E413D, Q428R, L429X, K431T  
NV_KTB002 02.KTB002 None None   K11S, V35T, T39K, D123N, K166R, K173T, D177E, T200E, Q207E, R211K, V245K, D250E, A272P, K275Q, T286A, E291D, I293V, E312D, I326V, I329V, Q334P, G335D, M357K, R358G, G359S, K366R, T369A, E370A, A371L, I375V, K390R, K395R, A400T, T403M, E404D, E432D  
NV_KTB026 02.KTB026 None None   E6D, K11Q, V35T, T39M, D121H, K122E, D123S, I135T, D177E, I202V, Q207N, R211K, P243A, I244V, V245K, A272P, T286A, E291D, V314I, V317A, Q334H, G335D, R356K, G359S, K366R, I375T, V381I, T386I, A400T, E404D, P421H, Q428R, K431T  
NV_KTB035 02.KTB035 None None   V21I, T27S, V35T, T39R, V60I, K122E, D123N, I135T, S162C, K173S, Q207N, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, V317E, I326V, Q334H, G335D, R356K, M357K, G359S, K366R, A371V, I375V, T377V, K390R, T403M, E404D, E432D, D471E, Q480H, H483Y, K512R, L517I, S519N, Q524K, K527E, V531I, A534S, Q547K, A554S  
NV_KTB038 02.KTB038 None None   E6K, K11A, V35T, T39K, K64R, K122E, D123S, I142V, K173A, Q174K, D177E, Q207A, R211K, K223R, V245K, D250E, T286A, E291D, V292I, I293V, P294T, E302G, I326V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376T, K390R, K395R, E399D, A400T, T403M, E432D  
NV_KTB041 02.KTB041 None None   V35T, E36D, D123E, I142V, K173A, Q174K, D177E, Q207E, R211K, V245Q, D250E, S251D, A272P, T290A, E291D, V292I, I293V, E297A, K311R, E312N, Q334K, G335D, R356K, M357R, G359S, K366R, T369V, Q373H, A376T, T377L, A400T, K431T  
NV_KTB053 02.KTB053 None None   V35T, E36D, K104R, S162A, K173A, Q174R, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294V, S322A, G335D, R356K, M357K, G359S, T369A, I375V, K390R, K395R, A400T, T403R, E432D, V435I  
NV_KTB145 02.KTB145 None None  V179D K20R, V35T, T39K, E40D, K49R, V60I, K122E, D123N, I135T, T139L, D177E, T200E, Q207T, R211K, F214L, V245Q, D250E, A272P, T286A, E291Q, V292I, I293V, P294T, K311R, S322A, G335D, R356K, M357R, R358G, G359S, E370A, A371V, I375V, A376V, T386M, K390R, A400T, L429X, K431T  
NV_KTB183 02.KTB183 None None   K20R, V35L, I135T, S162C, K173A, Q174K, D177E, Q207E, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, E297A, L310I, V314I, V317A, Q334H, F346Y, R358K, G359S, I375V, K390R, A400T, K431T  
NV_KTB220 02.KTB220 None None   V35T, K122E, D123E, S162C, K173A, Q174K, I202V, R211K, V245K, D250E, A272P, E291D, I293V, E297I, I326V, G335D, R356K, M357R, G359S, V365I, T377Q, E399D, A400T, K431T  
NV_KTB238 02.KTB238 None None   I5V, V35T, T39A, V60I, K104R, D121H, K122E, I132V, S162Y, E169D, K173A, Q174K, D177E, G196E, T200R, Q207E, R211K, V245T, D250E, A272P, K277R, K281R, T286A, E291D, V292I, I293V, E297R, K311R, Q334L, G335D, R356K, M357R, G359T, A371V, I375V, T377L, S379C, K390R, E399D, A400T, E404D, V435X  
NV_KTB242 02.KTB242 None None   V35T, T39R, S48T, V60I, K122E, D123N, I135T, K173S, Q174K, D177E, G196E, T200A, I202V, Q207A, R211S, V245I, D250E, S251H, A272S, T286A, E291D, V292I, I293V, P294T, E297A, V314A, D324E, Q334S, G335D, M357R, R358K, G359S, T377R, T386I, K390R, E399D, E404D, E413D R356T 
NV_LBDS072 02.LBDS072 None None   V35M, E36A, T39E, E40D, S48T, K173T, D177E, G196K, T200A, Q207E, R211K, P243A, V245Q, K249R, D250E, A272P, K277R, E291D, V292I, I293V, D324E, Q334H, G335E, R356K, G359T, T377Q, K390R, A400T, E404D, V435A  
NV_LBDS078 02.LBDS078 None None  K103N T27S, V35T, E36A, T39E, S48T, V60I, K122E, D123S, T139V, K173A, D177E, V179I, T200A, Q207E, R211K, K249Q, D250E, A272S, T286A, E291D, V292I, I293V, P313T, V317A, Q334H, G335E, R356K, G359T, A371V, I375V, T377M, T386I, K390R, A400T, E404D, V435A, F440Y  
NV_LBFE012 02.LBFE012 None None   K49R, V60I, K122E, D123S, T165I, R172K, D177E, I178L, E204K, Q207E, F214L, V245T, D250E, A272P, V276I, T286A, E297A, E312N, I329V, Q334E, V365I, K390R, T403R, V435I  
NV_LBFE069 02.LBFE069 None None   V35T, E36A, T39E, E40K, S48T, E53K, D76N, K103R, K122E, S162C, K173A, Q174K, D177E, T200A, E203D, R206K, Q207D, R211K, V245L, E248D, D250E, W252*, G262E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, G333R, Q334D, G335D, R356K, G359T, K366R, A376S, T377M, G384E, K390R, E399D, A400T, E404D, E430K, F440Y  
NV_LBIST051 LBIST051 None None   V35T, K49R, I50V, V60I, S105A, K122E, A158S, K173T, Q174K, D177E, Q197E, T200A, Q207E, V245Q, E248D, D250E, A272S, K275Q, E291D, V292I, I293V, E297A, D324E, I329V, Q334L, G335D, F346Y, A355S, R356K, M357R, R358G, G359S, A371V, A376S, T386I, K390R, Q394R, E399D, A400I, E404D, Q428R, K431T, V435P, F440Y  
NV_LBIST052 LBIST052 None None   V35T, T39R, V60I, K64R, K122E, D123G, S162C, K173T, Q174R, I195L, G196E, T200A, Q207E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T377L, S379C, T386I, Q394R, E396D, A400V, Q428R, K431T, V435P  
NV_LBR024 02.LBR024 None None   V35T, E36A, K49R, K122E, D123N, I135T, K173T, D177E, T200A, Q207A, R211K, P243S, V245K, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, Q334L, G335D, R356K, M357R, G359T, A371V, A376I, T377L, K390R, A400T, E404D, W410L, V417I, K431Q N81D 
NV_LBR032 02.LBR032 None None   V35K, V60I, K122E, D177E, I178M, V179I, Q207E, R211K, V245E, S251N, A272P, K275Q, K277R, T286A, I329V, Q334L, F346Y, R356K, A360T, T377Q, K390R, A400T  
NV_LBR060 02.LBR060 None None   V35T, T39K, K122E, Q145C, S162H, K173T, D177E, E194N, T200K, I202V, Q207E, R211K, V245Q, E248D, S251C, A272P, T286A, E291D, V292I, I293V, E297A, P313S, V317A, S322E, D324E, Q334R, G335E, F346Y, R356K, M357R, R358G, G359S, T369V, A371V, I375V, I380V, T386I, Q394R, A400V, E413D, V417I, K431T, V435P  
NV_LBS012 02.LBS012 None None   V35T, E36A, T39E, E40D, K43R, K122E, I142V, K173A, D177E, I195L, Q197K, T200A, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, Q334Y, G335D, R356K, M357R, G359T, K366R, T377M, K390R, A400V, E404D, E415V, V435A Q207I, E308L, W383Q, F416V 
NV_LBS024 02.LBS024 None None   V35T, V60I, K122E, K173S, Q174K, D177E, Q207A, V245Q, D250E, S251N, K281R, T286A, K287R, E291D, I293V, E312N, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376S, E399D, A400T, T403M, E404D, E432D, V435I  
NV_LBS035 02.LBS035 None None   V35T, V60I, K122E, I135V, S162C, K173A, Q174K, D177E, I178M, T200A, Q207E, P243A, V245Q, D250E, A272P, E291D, V292I, I293V, I329V, Q334A, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, A371V, A376S, Q394R, E399D, E404D, E413D, Q428R, K431T, V435A, A437V, F440Y  
NV_LBS038 02.LBS038 None None   V35T, E40D, K49R, V60I, K122E, E169D, D177E, Q207E, R211K, I244V, V245K, D250E, A272P, Q278N, T286A, K311R, D324E, Q334D, M357T, K390R, A400T, E413D, V435I  
NV_LBS048 02.LBS048 None None   E6K, V35T, E36A, T39E, S48T, K122E, A158S, K173A, Q174K, D177E, G196E, T200A, Q207E, R211K, V245K, A272P, K277R, E291D, V292I, I293V, E297A, Q334H, G335D, R356Q, M357I, G359T, I375V, T377R, S379C, K390R, A400T, E404D, I434M, V435L, A437V  
NV_LBS053 02.LBS053 None None   V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177Q, T200A, Q207E, R211K, V245L, K249Q, D250E, S251N, A272P, K277R, E291D, V292I, I293V, P294T, Q334H, G335E, R356K, G359T, T386V, K390R, A400T, E404D, L429X, I434X, V435A, F440Y  
NV_LBTB018 02.LBTB018 None None   P4S, V35T, T39A, E40D, K49R, K122E, D123E, I142V, D177E, T200A, Q207E, R211T, V245Q, E248N, V317A, M357A, T369A, S379G, K390R, A400T, V435I, F440L  
NV_LBTB028 02.LBTB028 None None   K20R, V35T, E36A, T39E, S48T, V118I, K122E, T139A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, D250E, S251D, A272S, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, K366R, T377V, K390R, A400T, E404D, E432D, V435I, F440Y  
NV_LBTB046 02.LBTB046 None None   V35T, T39R, S48T, V60I, K122E, D123S, K173A, D177E, G196V, T200A, I202V, Q207E, D250E, S251N, A272S, E291D, V292I, I293V, V314A, G335D, R356K, M357K, G359S, A371T, T377M, K390R, E399D, A400T, E404D, V435L, F440Y  
NV_MBFE101 02.MBFE101 None None   V35K, T39A, K102Q, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, V245L, E248D, D250G, A272P, T286A, E291D, V292I, I293V, P294T, K311R, E344A, R356K, M357K, R358G, G359S, E370A, A371V, I375V, S379G, K390R, T403M, L425S, E432D, V435A  
NV_MBFE252 02.MBFE252 None None   V35T, K49R, V60I, V118I, D121C, K122E, T165I, E169D, D177E, I178M, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, V292I, I293V, I329L, G333E, Q334Y, M357R, K390R, V435I  
NV_MBFE311 02.MBFE311 None None   P4H, I5V, E29K, V35T, M41I, K49R, K122E, D123S, R143K, W153*, D177E, I178M, R199K, T200K, R206K, Q207N, R211K, V245Q, E248D, D250E, A272P, K277T, E291D, V292I, I293V, E297A, I329V, Q334L, G335E, R356K, M357R, G359T, K366R, T369A, A371L, T377L, K390R, K395R, E396K, A400I, E404D, V435M  
NV_MBTB023 02.MBTB023 None None   P4H, V21I, V35T, T39A, V60I, I135V, S162C, K173T, Q174K, D177E, G196E, T200A, R211S, V245Q, D250E, A272S, T286A, E291D, V292I, I293V, E297A, D324E, I329V, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, T369A, Q394R, A400V, E404D, E413D, Q428R, K431T, V435P, A437V  
NV_MBTB047 02.MBTB047 None None   L34I, V35T, T39K, I50V, V60I, D123E, I142V, K173S, D177E, Q207A, R211K, I244V, V245I, D250E, E291D, V292I, I293V, P294T, E297K, E312D, R356K, M357R, R358K, G359S, A360T, T369A, A371V, I375V, A376T, T377M, K390R, E399D, A400T, K431T, V435X  
NV_MBTB090 02.MBTB090 None None   E28K, K32E, V35T, E36Q, T39A, K43A, D123E, S162C, K173T, Q174K, D177E, I195L, G196E, T200Q, Q207E, R211K, V245Q, D250E, S251D, A272P, K277R, T286A, E291D, V292I, I293V, P294V, E297K, D324E, I329V, Q334L, G335D, R356K, M357R, T369A, A376S, T377L, K390R, A400T, E404D, V435X  
NV_MBTB116 02.MBTB116 None None   V8I, V35T, E36A, T39E, S48T, K122E, D123S, K166R, K173A, D177E, T200V, Q207N, R211K, V245Q, E248N, S251N, A272P, K277R, T286A, E291D, V292I, I293V, V317A, Q334N, G335D, R356K, M357R, G359T, I375V, T377I, S379C, K390R, A400T, E404D, V435I