Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Gallant (2005)
Title Early virologic non-response to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral naive subjects.
Citation J Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 41
NumPts 41
Subtype B, A

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
JEG01 JEG01_w12 ABC, TDF, 3TC None M184V  K49Q, K166R, D177DE, I178IM, Q207E, V245E, D250E, A272P, K277R, R284RK, I293IV  
JEG02 JEG02_w12 ABC, TDF, 3TC None K65KR, M184V  E6EK, E53ED, R83RK, K122E, I135V, S162Y, D177N, R211RK, V245E, I293V  
JEG03 JEG03_w12 ABC, TDF, 3TC None K65R, M184V  R83RK, T200TA, R211K, V245K, K281KR, T286A, E297K  
JEG04 JEG04_w12 ABC, TDF, 3TC None K65KR, M184V  V35I, K64R, D123N, S162SN, D177E, Q197L, Q207E, E248N, A272P, V276I, I293V  
JEG05 JEG05_w12 ABC, TDF, 3TC None K65KR, M184V  R83RK, I178IM, T200A, E248D, A272S, V276I, Q278N, P294PT, E297EA  
JEG06 JEG06_w12 ABC, TDF, 3TC None M184V  T27S, V60I, R83K, K101Q, K103R, K122KE, D123E, I178M, V179I, T200A, V245E, I293V  
JEG07 JEG07_w12 ABC, TDF, 3TC None K65KR, M184MIV  K122KE, I178IM, Q207QH, R211K, D250E, K277R  
JEG08 JEG08_w12 ABC, TDF, 3TC None M184MIV  K11T, K20KR, V35T, E36D, T39R, E40D, V60I, D121H, K122E, D123S, I135T, I142V, S162HY, K173R, D177E, V179I, T200I, Q207A, R211RK, F214L, V245E, D250E, K275Q, T286A, E291D, V292I, I293V, P294T  
JEG09 JEG09_w12 ABC, TDF, 3TC None M184V  K20R, T69TN, D123DE, I135T, S162C, T200TIM, R211K, S251N, A272S  
JEG10 JEG10_w12 ABC, TDF, 3TC None K65KR, M184V  K122P, D123DE, I142IT, S162A, E169D, G196E, Q197K, I202V, Q207E, R211RK, F214FL, A272P, I293V  
JEG11 JEG11_w12 ABC, TDF, 3TC None K65KR, M184V  V90VI, K122KE, I135T, S162C, Q197QL, V245M, A272P, K277R, T286TA  
JEG12 JEG12_w12 ABC, TDF, 3TC None K70KE, Y115YF, M184V  V35I, V118I, K122E, I135R, I178IL, R211K, F214L, V245E, A288S, I293V, E297X  
JEG13 JEG13_w12 ABC, TDF, 3TC None M184V  V8I, V35I, R83K, K122KE, G196E, T200TI, I202V, R211G, S251I, A272X, V276I, K277KR, I293V  
JEG14 JEG14_w12 ABC, TDF, 3TC None K65KR, M184V  E53D, S162A, G196E, T200IR, Q207DE, L210LF, R211RK, V245E, S251I, K277R, I293V  
JEG15 JEG15_w12 ABC, TDF, 3TC None K65KR, M184V H221HY V21VI, V35VI, D123E, K173KT, Q174QR, D177E, G196E, T286TA, I293V, E297R  
JEG16 JEG16_w12 ABC, TDF, 3TC None M184MI  K20R, V60VI, K122KE, Q174KN, T200TA, E203D, Q207E, R211K, V245VE, A272P, I293IV, E297K  
JEG17 JEG17_w12 ABC, TDF, 3TC None K65KR, Y115YF, M184V  K122E, I135T, S162C, K201I, R211K, K277R, I293V, T296S, E297K  
JEG18 JEG18_w12 ABC, TDF, 3TC None K65R, Y115YF, M184V  D123E, I178M, I180V, R211K, A272P, T296TS  
JEG19 JEG19_w12 ABC, TDF, 3TC None K65R, M184V  K122E, I135T, R211K, T286TA, A288S, E297K  
JEG20 JEG20_w12 ABC, TDF, 3TC None K65KR, M184V  V35I, V60VI, R83K, D121Y, K122E, D177DE, I178IL, T200TA, R211RK, V245X, E248ED, A272P, T286A  
JEG21 JEG21_w12 ABC, TDF, 3TC None M184MV  V35M, R83RK, D123DE, S162C, D177E, I178V, G196E, T200A, E203Q, Q207QH, R211K, A272P, K277KR, A288AS, I293V, E297KR  
JEG22 JEG22_w12 ABC, TDF, 3TC None K65KR, M184MIV  K20R, V35I, T39TA, K82R, R83K, K166KR, K173Q, R211K, K249KR, Y271YF, A272P, T286A, V292I, E297K  
JEG23 JEG23_w12 ABC, TDF, 3TC None K65KR, M184V  E6D, K20KR, K101KR, K104KR, D123E, I135T, S162C, T200TA, R206RK, Q207EK, R211RK, V245VI, S251SC, A272P, V276VI, T286A, P294AS, E297A  
JEG24 JEG24_w12 ABC, TDF, 3TC None K65KR, M184V  V60I, V118I, D123E, I135IV, T165TI, D177E, T200A, R211K, F214L, V245I, E248D, A272P, K277R, T286A  
JEG25 JEG25_w12 ABC, TDF, 3TC None M41L, K65R, M184V, L210W, T215D  V60I, S68G, K122E, I135T, D177E, G196E, I202IV, R211K, V245T, D250E, A272P, K277R, E297A  
JEG26 JEG26_w12 ABC, TDF, 3TC None K65KR, M184MV  T7TI, R83RK, K122KE, E194ED, G196AV, T200TA, R211RK, A288S  
JEG27 JEG27_w12 ABC, TDF, 3TC None M184V  M16MV, K22KR, V35I, T69TN, R83K, K104R, K122KE, I178IM, R211RK, D250DG, A272P, I293V, E297A  
JEG28 JEG28_w12 ABC, TDF, 3TC None M184V  V35I, R83K, I135T, G196E, F214L, V245EK, V292I, I293V  
JEG29 JEG29_w12 ABC, TDF, 3TC None K65KR, M184V  K101KR, I142X, R211K, A272P, I274V, Q278N, I293V, E297T  
JEG30 JEG30_w12 ABC, TDF, 3TC None K65KR, M184MIV, K219R  V35L, S48T, K102Q, K104R, K122E, D123N, S162Y, E169D, K173KR, D177E, V179I, A272PS  
JEG31 JEG31_w12 ABC, TDF, 3TC None K65R, M184V  K20KR, V35R, S68X, D121Y, K122E, I135T, I142IL, T165I, I178V, E204A, R211K, F214L, V245E, A272P, K277R, V292I, I293V, E297T  
JEG32 JEG32_w12 ABC, TDF, 3TC None M184V V106VI, V179D T39A, R83RK, K122E, I135V, S162C, G196GE, T200A, R211G, E248D, A272P, A288S, E297K  
JEG33 JEG33_w12 ABC, TDF, 3TC None  K103N T69A, R83K, D121C, K122E, S162C, D177E, A272P, K277R Q23Q* 
JEG34 JEG34_w12 ABC, TDF, 3TC None K65KR, Y115YF, M184V  D86DE, D121DH, K122KE, I135IT, S162C, G196GE, R211K, T286A, V292I, I293IV  
JEG35 JEG35_w12 ABC, TDF, 3TC None M184V  I135V, S162C, D177E, G196E, R211K, V276I, L283I, T286A, I293V  
JEG36 JEG36_w12 ABC, TDF, 3TC None M184V  V35IT, T39A, S48E, D86E, D123E, K173N, Q174K, I178L, T200A, Q207D, R211K, V245N, D250E, A272P, V276T, K277R, T286A, I293V, E297Q  
JEG37 JEG37_w12 ABC, TDF, 3TC None M184V  A98S, D121H, K122E, I135T, V179I, T200TA, E204EK, A272S, I293V  
JEG38 JEG38_w12 ABC, TDF, 3TC None M184V  K32R, T69TA, I135T, T200A, I202V, R211K, I244V, V245K, E248D, D250E, A272P, T286A, V292I  
JEG39 JEG39_w12 ABC, TDF, 3TC None K70KE, M184V V106VI K122KE, D123E, S162Y, D177E, T200A, R211K, V245IM, A272P, I293V  
JEG40 JEG40_w12 ABC, TDF, 3TC None M184V  E6EK, T27S, I135T, A272P, K277R  
JEG41 JEG41_w12 ABC, TDF, 3TC None Y115YF, M184V  V35M, K122E, F171FY, R211K, F214L, V245K, A272P, K277KR, R284K, I293V