Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Gibb (2002)
Title Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial).
Citation Antivir Ther
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 157
NumPts 105
Subtype B, A, C, CRF02_AG, D, F, CRF01_AE, CRF12_BF, CRF18_cpx, CRF05_DF, H, CRF13_cpx, G

 
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Page 1   listing Isolate 1 to Isolate 100 from Total 157 Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
DMG1 1_w0 None    T12S, I15V, G16A, L19I, M36I, N37K, R41N, R57K, H69K, I93L  
DMG10 10_w0 None    I13V, K14R, M36I, R41K, H69K, L89M  
  10_w48 None    I13V, K14R, M36I, R41K, H69K, L89M T31TI 
  10_w56 None    I13V, K14R, M36I, R41K, H69K, L89M  
DMG100 100_w17 NFV 17   E35D, N37D, K43R, L63P, I64V, I93L  
  100_w41 NFV 41 M46MI, L90M  E35D, N37D, K43R, Q61QE, L63P, I64V, I93L  
  100_w73 NFV 73 M46I, L90M  E35D, N37D, K43R, I62IV, L63P, I64V, H69HY, V77VI, I93L  
DMG101 101_w0 None    T12S, I15V, L19I, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
DMG102 102_w51 NFV 52   I13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, L89M V32L 
DMG104 104_w66 NFV 66 N88S K20T, Q58QE T12S, I15V, L19I, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93L  
DMG105 105_w-2 None    I13V, E35D, M36I, R41K, R57K, H69K, L89M  
DMG106 106_w41 NFV 41 M46L N83D I13V, G16A, K20R, A22V, E35D, M36I, R41K, R57K, I64IV, H69K, L89M  
  106_w43 NFV 43   I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M  
DMG107 107_w-9 None    L10LI, T12S, I13V, L19LS, K20I, E35D, M36I, I64IM, H69K, K70KR, V82I, L89M  
DMG108 108_w-7 None    I15V, L19I, M36I, R41K, L63V, H69K, L89M, I93L  
  108_w28 NFV 28   L10V, I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89M  
DMG109 109_w-8 None    E35D, M36I, R41K, L63P, I64V, Q92K  
DMG11 11_w0 None    L10I, I13V, K14R, G16E, E35D, M36I, R41K, R57K, H69K  
  11_w31 None    L10I, I13V, K14R, G16E, E35D, M36I, R41K, R57K, H69K, L89M  
DMG112 112_w-38 None    R41K, I62IV, L63P, C67CS, V77VI  
DMG12 12_w0 None    T12S, I15V, K20R, M36I, R41K, Q61DN, H69K, L89M, I93L  
DMG13 13_w0 None    L10LI, V11I, I13V, I15V, K20V, M36I, N37S, R41K, H69K, L89M  
  13_w26 NFV 26   L10LI, V11I, I13V, I15V, K20V, M36I, N37S, R41K, H69K, L89M  
  13_w35 NFV 35   V11I, I13V, I15V, K20V, M36I, N37S, R41K, H69K, L89M  
DMG14 14_w0 None    I62V, L63A, V77I, I93L  
DMG15 15_w0 None    L10IV, I13V, K14R, G16E, K20I, M36I, R41K, C67H, H69K, K70R, L89M  
DMG16 16_w0 None    I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, H69K, L89M  
  16_w16 NFV 15   I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, H69K, L89M  
  16_w32 NFV 30   I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, H69K, L89M  
DMG17 17_w0 None    L10V, I13V, K14R, E35D, M36I, R41K, H69K, L89M  
DMG18 18_w0 None    E35D, R41K, I64V, V77I  
DMG19 19_w0 None    R41K, D60E, L63P, I64IV, H69Q, V77VI  
DMG2 2_w0 None    I13V, K14KR, E35D, M36I, R41K, H69K, L89M  
DMG20 20_w0 None    L10V, I13V, K14KR, I15IV, G16A, R41K, L63P, I64IV, H69HQ  
DMG21 21_w0 None    I13A, K14R, K20I, M36I, R41K, L63P, H69K, L89M  
DMG22 22_w0 None    T12TKN, L33V, N37C, I62V, L63P, H69Q  
  22_w32 NFV 32   T12N, L33V, N37C, I62V, L63P, I64L, H69Q  
DMG23 23_w0 None    L63S  
DMG24 24_w0 None    I64V, V77VI  
DMG25 25_w0 None    T12S, L63P  
DMG26 26_w0 None    I13IV, G16GA, R41K, L63PS, V77VI  
DMG27 27_w0 None    T12TS, I15IV, G16GE, G17GE, L19IT, K20KR, E35D, M36I, R41K, R57K, L63T, E65D, I72IT, L89M  
DMG28 28_w0 None    L10IV, I13V, I15V, R57K, L63P, H69N  
DMG29 29_w0 None    L10V, L63P, H69N  
DMG3 3_w0 None    I13V, E35D, M36I, R41K, H69K, L89M  
DMG30 30_w0 None    N37D, T74TA, V77IM  
DMG31 31_w-1 None    N37NT, L63P, I64V, H69N  
DMG32 32_w-22 None    L10I, T12I, I15V, G16E, E35D, M36I, R41RK, R57K, Q61N, L63T, G68GE, I72V, I93L  
DMG33 33_w-11 None    L19LI, E35D, N37D, L63P, H69N  
  33_w0 NFV 1   I13V, I15V, K20I, E35K, M36I, R41I, K43R, L63LP, H69K, L89M  
DMG34 34_w-1 None    T12S, I15V, L19I, R41K, L63V, H69K, T74S, V77I, L89M, I93IL  
DMG35 35_w0 None    I13V, I15V, N37D, I64V, H69K  
DMG36 36_w8 None    G17E, E35D, M36I, R57K, Q61N, L63T, E65ED, I72T, L89M  
  36_w13 None    I15IV, L63P, H69K, V77I L10KNT 
DMG37 37_w-5 None    T12A, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
DMG38 38_w-11 None    M36MI, R57K, L63P, I72IT  
DMG39 39_w0 None    I13V, E35D, M36I, L63PS, H69K  
  39_w19 NFV 19   G17GE, L19I, N37D, K43R, D60E, L63P, C67Y, H69K  
  39_w44 NFV 20 L90M  I13V, L19I, N37D, K43R, D60E, L63P, C67Y, H69K, A71V, V77VI  
DMG4 4_w0 None    K20R, M36I, N37D, R41K, L63S, H69K, L89M, I93L  
DMG40 40_w0 None    L10LI, I15V, K20KR, E35D, M36I, R41K, R57K, Q61DN, L63X, I93L  
DMG41 41_w0 None    E35D, N37S, R41K  
DMG42 42_w-3 None    I13V, K14R, I15IV, I62IV, L63P, I64IV, H69K, P79D  
  42_w26 NFV 13   T12TI, I13V, K14R, I15V, I62V, L63P, I64IV, H69K, P79D  
  42_w42 NFV 13   I13V, K14R, I15V, I62V, L63P, I64IV, H69K, P79D  
DMG43 43_w0 None    T12P, L19I, M36MI, I62IV, L63P, I93L  
  43_w26 NFV 27   T12P, L19I, M36MI, I62V, L63P, I93L  
DMG44 44_w0 None    L10V, T12A, K14KR, I15V, L63P, H69N  
  44_w34 None    L10V, T12TA, K14KR, I15V, L63P, H69N  
DMG45 45_w0 None    I13V, G16E, E35D, M36L, D60E, I62V, L63N, H69K, K70R, L89I  
DMG46 46_w0 None    L10I, E35D, L63T, I93L  
  46_w43 NFV 43   L10I, E35D, L63T, I93L  
  46_w48 NFV 48   L10I, E35D, I50IN, L63T, I93L  
DMG47 47_w0 None    I13V, I62IV, L63P  
DMG48 48_w-9 None    N37X, R41RK  
DMG49 49_w-2 None    L10I, E35D, N37D, R57RK, L63P, H69N, A71T  
  49_w32 NFV 8   T12S, K14R, G16GE, N37E, Q61QH, L63PST, I64ILV, E65ED, H69K  
  49_w33 NFV 9   L10I, E35D, N37D, L63P, H69N, A71T  
DMG5 5_w0 None    I13V, E35D, M36I, R41K, R57K, L63A, I64M, H69K, L89M  
DMG50 50_w-2 None    L63P  
  50_w21 None    I3IL, L63P, V77VI T26TA, R57RI 
  50_w33 None    M36I, L63P Q61Q* 
DMG51 51_w0 None    K14KR, L19I, E35D, N37T, R41K, R57RK, L63P, V77VI  
DMG52 52_w0 None    L10V, I15V, V77I  
DMG53 53_w-16 None    L10V, N37S, Q61E, L63P, C67Y, H69K, A71T  
DMG54 54_w0 None    K14KR, I15V, L19LI, L63V, I93IL H69IM 
  54_w25 None    K14R, I15IV, Q18QH, L19LI, L63V, I93IL H69IM 
  54_w48 None    K14R, I15V, Q18QHL, L63V H69M 
DMG55 55_w40 NFV 7     
DMG56 56_w-8 None    L33V, N37C, L63Q, I64V  
  56_w18 NFV 19   L33V, N37C, L63Q, I64V  
DMG57 57_w38 NFV 38   L10IV, I13IV, N37S, Q61E, L63P, C67Y, H69K, A71T, V77VI  
DMG58 58_w0 None    K14KR, E35D, N37D, L63P, H69KN, I72IV  
  58_w36 NFV 35   E35D, N37D, L63P, H69N, I72V T26TI 
DMG59 59_w7 NFV 7  K43T T12S, I15V, L19I, M36I, R41K, I62V, L63P, I64M, H69K, L89M, I93L  
  59_w32 NFV 32   I13V, M36I, R41K, L63S, I64IL, H69K, L89M, I93L L76LF 
  59_w38 NFV 38   Q7QH, I15IV, N37S, R57K, L63P, H69K K70KM 
  59_w52 NFV 53   L33V, N37C, L63Q, I64V  
DMG60 60_w34 NFV 34 D30N  L10V, I13V, G16E, M36I, K45X, I62V, L63H  
  60_w50 NFV 50 D30N  L10V, I13V, G16E, E35D, M36I, I62V, L63H  

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