Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rodes (2006)
Title Susceptibility to protease inhibitors in HIV-2 primary isolates from patients failing antiretroviral therapy.
Citation J Antimicrob Chemother
SelectedGene PR
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 6
NumPts 2
Host Human

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
RD_Pat1 SP2p1_75m None   S43T K7R, T12K, P19S, K70R, R72K, T91N, A92AT Y14C, N40S, L67V, N68G, S96T, L99F 
  SP2p1_91m LPV 69 V47A S43T K7R, T12K, K45R, I64V, K70R, R72K, T91N Y14C, N40S, L67V, N68G, S96T, L99F 
RD_Pat2 SP2p2_0m None   S43T G17D, N61ND, E65K, K70R Y14L, N40S, D79E 
  SP2p2_116m IDV, LPV 325 I54M, I82F S43T, I89IV V10I, E65K, K70R, V71I S4SF, Y14L, V33L, N40S, T56V, E58G, L93LS 
  SP2p2_126m IDV, LPV 373 I54M, I82F S43T, E58EG, I89V V10I, K70R, V71I Y14L, V33L, N40S, T56V, K60R 
  SP2p2_147m IDV, LPV 464 I54M, I82L S43T V10I, I15V, I64V, E65K, K70R, V71I Y14L, V33L, N40S, T56V