Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rey (2006)
Title Virologic response of zidovudine, lamivudine, and tenofovir disoproxil fumarate combination in antiretroviral-naive HIV-1-infected patients.
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 6
NumPts 6
Subtype B, CRF02_AG, C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
H3117 DR_H3117 TDF, AZT, 3TC None A62AV, K65R, K70KT, Y115YF, M184MV  T39E, S48T, S68R, V118I, T139A, K166R, K173T, D177E, T200E, Q207E, R211K, F214L, L228LR, V245T  
H3198 DR_H3198 TDF, AZT, 3TC None K65KR  D123E, I132IL, I135T, I142IV, K166KR, Q207E, V245K  
H3680 DR_H3680 TDF, AZT, 3TC None D67NT, K70R, M184V, K219KE E138EK D123E, R211K, V241VI, V245T  
H3694 DR_H3694 TDF, AZT, 3TC None M41L, M184V, T215F  S68T, D123E, T139K, I178IM, V179I, R211Q  
H3794 DR_H3794 TDF, AZT, 3TC None   T39I, K102KE, D123DG, S162A, K173T, D177E, I178M, T200A, Q207E, R211K, V245Q  
M31231 DR_M31231 TDF, AZT, 3TC None M41L, T215N  I135V, S162A, D177E, I178V, V245M