Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Winters (2000)
Title Genotypic, phenotypic, and modeling studies of a deletion in the beta3-beta4 region of the human immunodeficiency virus type 1 reverse transcriptase gene that is associated with resistance to nucleoside reverse transcriptase inhibitors.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 7
NumPts 7
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
q020 q020 NRTI NNRTI A62V, K70~, V75I, F77L, Y115F, F116Y, Q151M, M184V  S68G, T69S, K101Q, K122E, S162C  
q489 q489 NRTI NNRTI K65R, T69~, K219R Y181C, H221HY V35L, S48E, S68G, D123E, A158S, Q197E, R211K, F214L  
q514 q514 NRTI NNRTI A62V, T69~, V75T, Q151M  S68G, T200A, Q207E, R211K, F214L, I257L, A272P  
q712 q712 NRTI NNRTI D67~, T69G, K70R, T215F, K219E K103N, Y181C, G190GA K20R, A98S, K102E, I135T, Q197K, I202IV, R211K, V245K, A272P  
q759 q759 NRTI NNRTI A62V, D67N, T69~, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219E K101E, Y181C, G190A V35L, S68G, K122E, I135T, R172K, E203EQ, R211K  
v1966 v1966 NRTI NNRTI M41L, D67~, T69G, K70R, L74I, T215F, K219Q L100I, K103N E6D, K20R, T39N, K43E, K102R, D123E, K166R, D177E, V179I, G196K, T200I, Q207E, L228LR, V245K, A272P, K277R, I293V  
v620 v620 NRTI NNRTI A62V, T69~, V75T, Y115F, Q151M, M184V A98G, V108I, Y181C K20R, K22R, I31R, S68G, K122E, F214L, K277Q, V292I, I293V