Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Machado (2004)
Title Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy.
Citation J Clin Virol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 74
NumPts 74
Subtype B, F, B + F, CRF05_DF, CRF12_BF, C

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
con01 con01 None    T12S, E35D, N37H, R41K, L63P, V77I, I93L  
con03 con03 None    I15V, H69Y  
con04 con04 None    K14R, N37E, L63P  
con08 con08 NFV 18   I13V, E35D, R41K, R57K, L63P, H69R  
con09 con09 NFV 12   L63P, H69Q, V77I  
con11 con11 None    I15V, G17E, E35D, L63P, I93L I85F, R87T 
con12 con12 RTV 81 M46I, V82L F53L L10I, T12S, G16A, E35D, M36I, N37D, I64V, H69K, K70E, V77I, C95S  
con14 con14 RTV 61 M46I, I54V, V82A  K14R, I15V, E35D, R41K, L63P  
con15 con15 None    G17D, L63P, K70R  
con17 con17 RTV 74   G17E, E35D, L63P  
con20 con20 RTV 68   I15V, M36I, N37K, R41N, H69K, L89M  
con21 con21 None  V82L L24I E35D, M36I, R41K, R57K, Q61N, L89M  
con22 con22 None    K14R, R41K, D60E, Q61E, I62V, L63P, V77I  
con23 con23 None    M36I, L63P, H69Q, C95S  
con25 con25 None    I15V, K70R, V77I, C95S  
con28 con28 None    T12I, K14R, I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, L89M  
con29 con29 NFV 54   L63P, H69K  
con30 con30 None    I15L, G17E, E35D, L63P, C95S  
con31 con31 None    G17E, E35D, G40R, L63P, H69Y  
con32 con32 RTV 87 L90M  L10I, L19I, N37S, L63P, V77I  
con33 con33 None    I15V, K43I  
con34 con34 None    I13V, I64V, C95S  
con39 con39 NFV 60   G17E, R57K, L63P, K70R, L89F, C95S  
con45 con45 RTV 96 V82L  D60E, L63M, I64V, H69Y, I93L  
con50 con50 None    L19I, N37S, I64V, H69Y, I72V, C95S  
con52 con52 None    N37S, L63P, H69Q, V77I, C95S  
con55 con55 RTV, NFV 40   N37S, L63A, C95S  
con57 con57 None    L10I, L33V, L63P, I93L, C95S  
con58 con58 None    L33V, L63P, C95S  
con59 con59 None    L10I, R57K, L63P, I64V, K70R, C95S  
con60 con60 None    I13V, N37A, R57K, L63P, H69R, C95S  
con61 con61 None    L10I, N37D, C95S  
cs120 cs120 RTV 160 M46I  R8Q, L10I, K20R, E35D, M36V, N37D, L63P, H69Q, V77I, V82I, C95S  
cs121 cs121 None    L63P, C67Y, H69K, C95S  
cs122 cs122 None    T12R, L19I, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, L89M, C95S  
cs124 cs124 NFV 74 D30N, V82L  N37S, K45R, L63P, A71T, C95S  
cs125 cs125 NFV 94 D30N  L10I, I13V, E35D, M36I, L63P, I64V, H69Q, V75I, C95S  
cs126 cs126 NFV 99   I15V, E35D, M36I, L63P, C95S  
cs127 cs127 RTV 149 V82L  K14R, I62V, L63H, C95S  
cs128 cs128 NFV 99   I15V, E35D, M36I, L63P, C95S  
cs129 cs129 None    M36I, N37D, H69K, C95S  
cs130 cs130 None    T12N, L19I, E35D, N37S, R41K, I64V, A71V, V77I, I93L  
cs131 cs131 None    M36I, R57K, L63P, C95S  
cs132 cs132 RTV 146 M46L, I54V, V82A, L90M Q58E K20R, E35D, M36I, R57K, I62V, L63P, I64V, A71V, V77I, C95S, L97F  
cs133 cs133 RTV 155 M46L, I54V, V82A L24I L10I, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89M  
cs134 cs134 NFV 214 D30N L10F, N88D T12N, L19V, K20I, E35D, M36I, I64V, A71V, C95S  
cs135 cs135 NFV 113 V32I, M46I, I54V, V82A, L90M K43T L10I, I15V, K20R, M36I, R57K, L63P, A71V, C95S  
cs136 cs136 RTV 142 M46L, I54V, V82A  L10I, G17D, N37S, I64V, H69Y, C95S  
cs138 cs138 None    K14R, I15V, E35D, M36I, R41K, R57K, Q61N, V77I, L89M, C95S  
cs139 cs139 None    T12D, K14R, I15V, G16E, L19T, E35D, M36I, P39Q, R41K, R57K, Q61N, L63V, I72T, V77I, L89M, C95S  
cs140 cs140 None    I15V, L38I, I62V, I64V, C67S  
cs141 cs141 RTV, NFV 160 I84V, L90M F53L L10I, I13V, K20R, E35D, M36I, N37S, R41K, I62V, L63P, I64V, H69Y, A71V  
cs142 cs142 NFV 93 D30N, M46L  I64V, A71V  
cs143 cs143 NFV 89 M46I, L90M  L10I, G16E, L19V, K20I, R41K, R57K, A71T, T74S, V77I, Q92K  
cs144 cs144 None    L63P, C67Y, H69K  
cs146 cs146 RTV 156 I54V, V82A, L90M Q58E L10I, K20R, M36I, R41K, I62V, L63P, H69R, A71V  
cs147 cs147 RTV 144 I54V, V82T, L90M  L63P, A71V, I72V, V77I  
cs148 cs148 None    T12I, L33V, R41K, R57K, Q61E, L63P, I64V  
cs149 cs149 RTV, Unknown 106 I54V, V82M L24I L10I, I15V, G17E, L19I, E35D, M36I, N37D, R41K, D60E, Q61E, L63P, H69R  
cs150 cs150 None    I15V, L19I, K20M, E35D, M36I, R41K, D60E, I62V, L63P  
cs151 cs151 None    G17E, D60E, L63P  
cs152 cs152 None    I15V, K43R, L63P  
cs154 cs154 None    I62V, L63T, I64V, H69K, N98K  
cs155 cs155 NFV I54V, V82A, L90M  K14R, L19V, N37S, L63P, A71V, V77I  
cs156 cs156 None    L10V, I15V, E35D, M36I, R41K, R57K, D60E, Q61N, L63S, I72V, V77I  
cs157 cs157 None    L10V, E35D, M36I, R41K, Q61N, L63S, E65D, V77I, L89M  
cs160 cs160 RTV 163 I54V, V82A, L90M  L10I, K20R, M36I, I62V, L63P, A71V  
cs163 cs163 None    G17E  
cs189 cs189 NFV 48 L90M K20T I15V, E35D, M36I, N37D, P39Q, R41K, R57K, D60E, Q61D, L89I  
cs190 cs190 NFV 24 I54V K20T L10I, I15V, E35D, M36I, N37E, P39Q, R41K, R57K, D60E, Q61D, H69Y  
cs195 cs195 NFV 128 D30N, M46I L33F, N88D I15V, K20I, R57K, D60E, L63P  
cs196 cs196 NFV 93 M46I, N88S  L10I, T12S, I13V, L19I, K20I, E35D, N37H, R41K, K45R, L63P, V77I  
cs199 cs199 RTV 75 M46L, I54V, V82A L24I L10V, I15V, G16E, L19I, K20R, E35D, M36I, R57K, Q61D, L63V, E65D  
cs200 cs200 RTV, Unknown, NFV 150 D30N, M46I K20T, N88D I13V, I15V, L63P, H69Q, V77I