Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Clevenbergh (2002)
Title Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1.
Citation Antivir Ther
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 12
NumPts 12
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CP0303 CP0303 NRTI, AZT, 3TC NVP M41L, A62AV, T69T_SSG, M184MIV, L210W, T215Y A98G, Y181YC E40EK, K43E, K101KR, V118VI, K122KE, I135X, S162C, D177E, V179VI, T200A, R211K, L228H, Q242QK  
CP0402 CP0402 NRTI, D4T, DDI None D67N, F77FL, F116Y, Q151M  K122E, I135M, S162A, Q197E, V245VE  
CP0720 CP0720 NRTI, ABC, AZT, 3TC NVP K70R, F77FL, F116Y, Q151M, M184V, K219Q A98G, V108VI, Y181C T39A, K43Q, D67X, T69N, K101X, D113DN, D123E, S134SG, S162Y, D177E, V179I, T200X, E203ED, Q207QH, D218E  
CP0909 CP0909 NRTI, AZT, 3TC NVP A62V, V75I, F77L, Y115YF, F116Y, Q151M, M184V, K219N K103KN, Y181C, G190GA, M230MI E42EG, K101KQ, K122E, I132IV, S134SG, N137NI, T165TK, D177DE, D192DN, W229WG, P243PL N81NY, N136NKT, P140PL, G141GW, I159IK, I178IK, D186DY 
CP0934 CP0934 NRTI, AZT, 3TC NVP K65R, K70R, F77L, F116Y, Q151M, M184V K103N, V108VI S68G, K122E, D218DE  
CP0936 CP0936 NRTI, ABC, AZT, 3TC NVP F116Y, Q151M, M184V, K219N G190E V75VL, R83K, K101KR, D123E, I178M, V245EK  
CP0937 CP0937 NRTI, D4T, DDI None A62V, D67E, T69S_SG, K70R, T215F  V118VI, K122E, D123S, D177DE, Q207E, R211K  
CP1201 CP1201 NRTI, 3TC, D4T EFV A62V, V75I, F77L, F116Y, Q151M, M184V G190S S68G, T69N, K101Q, I202V, R206RK, F214L  
CP1303 CP1303 NRTI, D4T, DDI EFV M41L, D67N, K70R, L74I, V75T, T215F, K219Q L100I, K103N, H221HY V111I, I135T, Q151X, T165I, D177DN, G196E, I202V, F214L, D218DE, L228H Q222Q* 
CP1801 CP1801 RTI, ABC, AZT, 3TC RTI K65R, K70R, V75I, F77L, F116Y, Q151M, M184MIV K101KE, V108I, G190A S48T, S68G, V90VI, K122E, K166R, K219X, V245K  
CP1803 CP1803 NRTI, ABC, AZT, 3TC None V75VIL, F77L, Y115F, F116Y, Q151M, M184V, K219KE K101E, K103KN, V108I, Y181C, G190A S68G, V111X, D123E, I178L, F214L T69H, D110DE 
CP1902 CP1902 NRTI, 3TC, D4T None A62V, V75I, F77L, Y115F, F116Y, Q151M Y181C T69N, K122E, K173Q, Q174R, I202V, Q207E, R211K, V245T