Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sevigny (2004)
Title Cross-resistance profile of the novel lysine-containing HIV-1 protease inhibitor PL-100.
Citation IHDRW 2004
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 14
NumPts 14
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
SG_pat1 MLpat1 Unknown  I54V, V82A, I84V L24I, L33F L10I, M36I, L63P, A71V  
SG_pat10 MLpat10 Unknown  M46I, V82T, L90M F53L, G73S L10I, L63P, A71V  
SG_pat11 MLpat11 Unknown  M46I, V82T, I84V  L10LI, L63P, A71V, I93L  
SG_pat13 MLpat13 Unknown  M46I, V82T, I84V L10F K20KR, L63P, A71V, V77VIM, I93L  
SG_pat15 MLpat15 Unknown  M46I, V82T, I84V, L90M G73A L10I, K20I, M36I, L63P, A71V  
SG_pat16 MLpat16 Unknown  M46I, I84V, L90M L10F, N88D L33I, M36I, L63P, A71I  
SG_pat21 MLpat21 Unknown  I84V, L90M L10F L63A, A71V  
SG_pat24 MLpat24 Unknown  I50V L33F L10I, M36L  
SG_pat26 MLpat26 Unknown  G48V, I54V, V82A, L90M  L10I, L63P, A71V, I93L  
SG_pat28 MLpat28 Unknown  D30N, L90M N88D L63P, V77I, I93L  
SG_pat3 MLpat3 Unknown  M46L, I54L, V82A L24I, L33F L10I, K20R, M36I, L63C  
SG_pat5 MLpat5 Unknown  I54V, V82A, I84V, L90M  L10I, K20I, M36I, D60E, L63P, A71I  
SG_pat6 MLpat6 Unknown  I54V, V82A, I84V, L90M K20T, L33F, G73S L10V, M36I, D60E, L63P, A71V  
SG_pat7 MLpat7 Unknown  M46I, I54V, V82A, I84V, L90M L33F L10I, L63P, A71V