Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Apetrei (2003)
Title HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 77
NumPts 58
Subtype F, C

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
AC_Pat1 RO.00.IS.01 IDV, Unknown  M46I, I54V, V82A L24I, K43T L10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
  RO.01.IS.01 IDV, Unknown, SQV, NFV  M46I, I54V, V82A, I84V L24I, K43T, F53L L10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M G48W 
AC_Pat1_a RO.00.IS.11 Unknown    I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, L89M  
  RO.01.IS.11 Unknown    L10V, I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat2 RO.00.IS.02 IDV    I15V, G16E, Q18E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T  
AC_Pat20 RO.00.IS.20 IDV    I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
  RO.01.IS.20 IDV, RTV    I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat21 RO.00.IS.21 IDV    I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89M  
  RO.01.IS.21 IDV    T12I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89M  
AC_Pat22 RO.00.IS.22 IDV, RTV, NFV  I54V, V82A  L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M  
AC_Pat23 RO.00.IS.23 IDV  V82A  I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89M  
  RO.01.IS.23 IDV, SQV, NFV  V82A  L10V, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72T, L89M  
AC_Pat24 RO.00.IS.24 IDV  V82A  L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89M  
AC_Pat25 RO.00.IS.25 IDV    L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T  
  RO.01.IS.25 IDV  G48V, V82A  L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T  
AC_Pat26 RO.00.IS.26 IDV    L10V, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72V, T74S, L89M  
  RO.01.IS.26 IDV, RTV  M46I, I54V, V82T, I84V  L10V, I15V, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72V, T74S, L89M  
AC_Pat27 RO.00.IS.27 IDV    T12S, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, L89M  
  RO.01.IS.27 IDV    T12S, I15V, L19V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, L89M  
AC_Pat28 RO.00.IS.28 IDV    I15V, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat29 RO.00.IS.29 IDV    T12S, I15V, G16E, K20R, E35D, M36I, R57K, L63T, E65D, I72T, L89M  
AC_Pat30 RO.00.IS.30 IDV, RTV, SQV, NFV    T12S, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M, Q92K  
AC_Pat31 RO.00.IS.31 IDV    T12S, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89M  
  RO.01.IS.31 IDV, SQV, NFV    T12S, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89M  
AC_Pat32 RO.00.IS.32 IDV    L10I, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M, I93L  
  RO.01.IS.32 IDV, NFV    L10I, I15V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M, I93L  
AC_Pat33 RO.00.IS.33 IDV    L10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72V, L89M  
  RO.01.IS.33 IDV, NFV    L10V, I13V, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, I72V, L89M  
AC_Pat34 RO.00.IS.34 IDV    L10V, T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M  
AC_Pat35 RO.00.IS.35 IDV    L10V, I15V, G16E, E35D, M36I, R41K, R57K, I62V, L63T, E65D, L89M  
AC_Pat36 RO.00.IS.36 IDV, RTV, SQV, NFV  M46L, I54V, V82A  L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, K70E, I72T, L89M  
AC_Pat37 RO.00.IS.37 IDV, RTV  L90M K20T L10V, T12S, I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, T74S, L89M  
AC_Pat39 RO.00.IS.39 IDV    I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M  
AC_Pat3_a RO.00.IS.13 Unknown    T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63A, L89M  
  RO.01.IS.13 Unknown    T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63A, L89M  
AC_Pat4 RO.00.IS.04 IDV, SQV, NFV    L10V, T12S, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat40 RO.00.IS.40 IDV  M46I, I54V, V82A  L10V, I15V, G17E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat41 RO.00.IS.41 IDV    T12I, I15V, G16E, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat42 RO.00.IS.42 IDV 25   L10V, T12S, I15V, L19V, K20R, E35D, M36I, R41K, R57K, I62V, L63T, L89M, I93L  
AC_Pat43 RO.00.IS.43 IDV    T12N, I15V, G16E, K20R, E35D, M36I, R57K, I62V, L63T, E65D, I72T, L89M  
AC_Pat44 RO.00.IS.44 IDV, RTV, SQV, NFV    I15V, K20R, L23V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L97I C95N 
AC_Pat45 RO.00.IS.45 IDV  I54V, V82A  L10V, I15V, K20R, L23V, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat46 RO.00.IS.46 IDV, Unknown, SQV, NFV    I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat47 RO.00.IS.47 IDV    T12S, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, V82I, L89M  
AC_Pat49 RO.00.IS.49 Unknown    T12S, I15V, G16E, K20R, E35D, M36I, R57K, D60E, Q61E, L63T, E65D, I72T, L89M  
AC_Pat4_a RO.00.IS.14 Unknown  V82A  I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, I72T, T74S, L89M  
AC_Pat5 RO.00.IS.05 IDV  M46I, I54V, V82A  L10I, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89M  
AC_Pat50 RO.00.IS.50 Unknown    L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69Y, I72T, I93L  
  RO.01.IS.50 Unknown    L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69Y, I72T, I93L  
AC_Pat51 RO.01.IS.51 Unknown  M46I, I54V, V82F K20T, Q58E L10V, I15V, G16E, E35N, M36I, P39Q, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat52 RO.01.IS.52 Unknown    T12A, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, I72T, V82I, L89M  
AC_Pat53 RO.01.IS.53 Unknown    P39Q, R41K, L63V, H69K, L89M, I93L  
AC_Pat56 RO.01.IS.56 Unknown    L10I, T12S, I13V, I15V, G16E, E35D, M36I, R41K, R57K, D60E, I62V, L63T, I64M, E65D, L89M, I93L  
AC_Pat57 RO.01.IS.57 Unknown    T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, L63T, E65D  
AC_Pat5_a RO.00.IS.15 Unknown    L10V, V11I, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat6 RO.00.IS.06 IDV, RTV, NFV    I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93L  
  RO.01.IS.06 IDV, RTV, NFV, Unknown   K20T L10V, I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93L, F99Y  
AC_Pat60 RO.01.IS.60 Unknown  M46L, V82A  L10V, T12S, I15V, G16A, L19V, K20R, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72T, L89M, I93L  
AC_Pat62 RO.01.IS.62 Unknown  M46I, I54V, V82A K43T L10I, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, I62V, L63T, E65D, I72V, T74K, L89M  
AC_Pat63 RO.01.IS.63 Unknown  M46I, I54V, V82A, L90M Q58E L10V, I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, L63T, E65D, I72T, L89M  
AC_Pat64 RO.01.IS.64 Unknown  M46I, I54V, V82A  L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, I72T, L89M, I93L  
AC_Pat65 RO.01.IS.65 Unknown  M46I, I54V, V82A L24I, Q58E L10I, I15V, G17D, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, I72T, T74K, L89M  
AC_Pat69 RO.01.IS.69 Unknown  V82A  L10V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, T74S, L89M  
AC_Pat6_a RO.00.IS.16 Unknown  M46L, V82A  L10V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, L63T, E65D, I72T, L89M, I93L  
  RO.01.IS.16 Unknown  M46L, I54V, V82A  L10I, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, L63T, E65D, A71V, I72T, L89M, I93L  
AC_Pat7 RO.00.IS.07 IDV, SQV, NFV, Unknown  M46L, I54V, V82A  L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
  RO.01.IS.07 IDV, SQV, NFV, Unknown  M46L, I54V, V82A  L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat70 RO.01.IS.70 Unknown  M46I, V82F  L10I, T12S, I13V, I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, Q61E, I62V, L63T, E65D, L89M I47T 
AC_Pat71 RO.01.IS.71 Unknown  L90M  L10V, I15V, G16E, K20R, E35D, M36V, P39S, G40E, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat73 RO.01.IS.73 Unknown  V82A  L10V, I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63T, E65D, T74S, L89M  
AC_Pat7_a RO.00.IS.17 Unknown    K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
  RO.01.IS.17 Unknown  M46L, V82A  K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
AC_Pat8 RO.00.IS.08 IDV, Unknown, SQV, NFV    T12S, I15V, Q18E, L19T, K20R, E35D, M36I, R41K, R57K, L63T, E65D  
  RO.01.IS.08 IDV, Unknown, SQV, NFV, RTV    T12S, I15V, Q18E, L19T, K20R, E35D, M36I, R41K, R57K, L63T, E65D  
AC_Pat8_a RO.00.IS.18 Unknown    L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M  
  RO.01.IS.18 Unknown    L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M  
AC_Pat9_a RO.00.IS.19 Unknown    I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, I62V, L63T, E65D, I72T, L89M