Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Monno (2003)
Title Mutational patterns of paired blood and rectal biopsies in HIV-infected patients on HAART.
Citation J Med Virol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 17
NumPts 10
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
ML_pt10 ML131 IDV, NFV 34 N88S  L10I, I13V, K20R, N37D, L63P, A71T, V77I  
  ML131A IDV, NFV 34 I50V  N37S  
ML_pt11 ML125_1 RTV, SQV, NFV 24   I13IV, K14KR, N37S, I64IV  
  ML132LASO RTV, SQV, NFV 24 I50V  N37S  
ML_pt12 ML125_2 IDV 17   N37S, L63A, I72V, V77I, I93L  
  ML134 IDV 17 I50IV  L5LF, R57RG, I62IV, L63X, I72IV, V77VI V56IL 
ML_pt13 ML135 RTV, IDV, NFV, SQV 40 V32I, M46I, I54V, V82A, L90LM F53L L10V, I15V, G16GA, M36L, L38V, P39Q, R41K, L63P, A71V, I72V  
ML_pt14 ML136_1 IDV, NFV 26 V82A  L10I, L19IV, L38V, R41K, I62V, L63P, A71T, V77I  
  ML136_2 IDV, NFV 26 I50V  Q18QH, N37S, Q61QH, I93IV R87RG 
ML_pt2 ML126_2 IDV 13 I50V  N37S  
  ML126_1 IDV 13   I3V, N37S  
ML_pt6 ML127_1 SQV, RTV, IDV 20   N37D, L63H G94GA, L97LS 
ML_pt7 ML128_2 RTV, IDV 26 V32I, M46I, V82A, L90M  K20R, M36I, L63P, C67Y, H69K, A71V, I72V  
  ML128_1 RTV, IDV 26  L33LF M36MI, L63P, C67Y, H69K, A71AV, I72IV  
ML_pt8 ML1229 SQV, IDV 26 I50V  G16GR, N37S, L63LP  
ML_pt9 ML1030_1 SQV, IDV 16 I54V, I84IV, L90M G73S T4S, L10I, K20R, E35D, M36I, K45R, I47IM, I62V, L63P, C67F, H69N, A71V, I72IL  
  ML1030_2 SQV, IDV 16 V82VA  L63P