Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Brandin (2003)
Title Pol gene sequence variation in Swedish HIV-2 patients failing antiretroviral therapy.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 30
NumPts 12
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
BE_Pat1 Pat1 D4T, DDI None   M11S, K20R, P126Q, H162Y, I180L, R200K, H228Q, I244L V2I, V5I, K9R, I10V, R22K, R104K, S134A, K176P, D195G, V201A, Y227F 
BE_Pat10 Pat10_00 None None   K64R, K82R, P126Q, H162Y, K176Q, R200K V5I, I8M, M11V, V167I 
  Pat10_01 AZT, 3TC, DDI None K65R, Q151M, M184V  K64R, N69S, K82R, V111I, P126Q, K176Q, R200K, F214L, H228Q I8M, I10V, M11V, V167I 
BE_Pat11 Pat11 None None   M11T, K43R, D86E, P126Q, V135T, H162Y, K176S, R200K, H228R, K249R V5I, I8V, I10V, R22K, I90V, H121W, S134A 
BE_Pat16 Pat16 None None   M11T, K43R, P126Q, H162Y, I180L, H228Q V5I, M73MK, V83VL, R104K, I145T, V167I, K176P, V201A 
BE_Pat18 P18_00_04 D4T, DDI, AZT, 3TC, ABC None Q151M  K43R, H121Y, P126Q, H162F, K176Q, K223R V5I, I10V, V135I, V167I 
  P18_00_06 D4T, DDI, AZT, 3TC, ABC None Q151L  K43R, H121Y, P126Q, H162F, K176Q, K223R V5I, I10V, V135I, V167I 
  P18_00_10 D4T, DDI, AZT, 3TC, ABC None Q151M  K43R, H121Y, P126Q, H162F, K176Q, K223R V5I, I10V, V135I, V167I 
  Pat18_01 D4T, DDI, AZT, 3TC, ABC None   K43R, P126Q, V135T, H162F, K176Q, H228Q V5I, I10V, V167I 
BE_Pat19 Pat19 None None   M11T, K43R, K64R, D86E, P126Q, V135T, H162Y, R200K, H228R V2I, V5I, I8V, I10V, R22K, I90V, H121W, S134A, K176P 
BE_Pat2 Pat2_97 AZT None   M11T, K43R, T88S, V111I, P126Q, V135T, H162Y, I180L, D192N, R200K, H228R V5I, I10V, P51S, I90V, M164T, V167I, K176P, V178I, V201A 
  Pat2_00 AZT, 3TC, D4T None   M11T, D86E, V111I, P126Q, A138T, H162Y, I180L, H228R V5I, I10V, P51S, I90V, M164T, V167I, K176P 
  Pat2_01 AZT, 3TC, D4T None   M11T, K43R, T88TS, V111I, P126Q, H162Y, I180L, R200K, H228R V5I, I10V, P51S, I90V, M164T, V167I, K176P, V201A 
BE_Pat24 Pat24 None None   K35R, K43R, K64R, R72K, H162Y, K176Q, R200K V83I, S134A, V201A 
BE_Pat3 Pat3 None None   T27S, K43R, K82R, D86E, H121Y, P126Q, H162Y, I180L, H228R V5I, I8V, I10V, I90V, K176P, V201A 
BE_Pat4 Pat4_92 AZT None   M11A, K43R, P126Q, H162Y, K173R, K176S, G211N, E219D, H228R V5I, K147R 
  Pat4_94 AZT None   M11A, P126Q, H162Y, K173R, K176S, G211N, E219D, H228R K147R, G152R 
  Pat4_97 AZT None M184V  M11A, P126Q, H162Y, K173R, K176S, G211N, E219D  
  Pat4_99 AZT, 3TC, D4T None M184V  M11T, P126Q, H162Y, K173R, G211N, E219D I10V, K176P 
  Pat4_00 AZT, 3TC, D4T None M184V  M11T, P126Q, H162Y, K173R, G211N, E219D, W239G I10V, K176P 
  Pat4_01 AZT, 3TC, D4T None M184V  M11T, P126Q, H162Y, K173R, G211N, E219D I10V, K176P 
  Pat4_02 AZT, 3TC, D4T, ABC, DDI None M184V  M11T, P126Q, H162Y, K173R, G211N, E219D I10V, K176P 
BE_Pat5 Pat5 None None   M11T, K28R, K43R, D86E, F87L, P126Q, H162Y, I180L, H228Q V5I, I10V, R104K, V135I, V167I, K176P, Y227F 
BE_Pat8 Pat8_95 None None   M11S, K20R, K82R, V111I, P126Q, H162Y, I180L, R200K, H228Q, I244L V5I, R22K, P51S, R104K, A138M, K176P, D195G, Y227F 
  Pat8_97 AZT, 3TC None M184V  M11S, K20R, K82R, V111I, P126Q, H162Y, I180L, R200K, H228Q, I244L V5I, I10V, R22K, P55L, R104K, A138M, K176P, D195G, Y227F 
  Pat8_00 AZT, 3TC, D4T, DDI None M184V  M11S, K35R, K82R, V111I, P126Q, H162Y, I180L, R200K, E219D, H228Q, I244L V5I, I10V, R22K, R104K, A138M, K176P, D195G, Y227F 
  P8_01_04_1 AZT, 3TC, D4T, DDI None K70S, M184V  M11S, K20R, K35R, K82R, V111I, P126Q, H162Y, T163A, I180L, R200K, G211S, H228Q, I244L V5I, I10V, R22K, R104K, A138I, K176P, D195G, Y227F 
  P8_01_04_2 AZT, 3TC, D4T, DDI, ABC None K70S, M184V  M11S, K35R, K82R, V111I, P126Q, H162Y, T163A, I180L, R200K, H228Q, I244L V5I, I10V, R22K, R104K, A138M, K176P, D195G, Y227F 
  Pat8_01_08 AZT, 3TC, D4T, DDI, ABC None K70S, M184V  M11S, K35R, K40R, K82R, V111I, P126Q, H162Y, T163A, I180L, R200K, H228Q, I244L V5I, I10V, R22K, R104K, A138M, K176P, D195G, Y227F 
  Pat8_01_11 AZT, 3TC, D4T, DDI, ABC None K70S, M184V  M11S, K35R, K40R, K82R, V111I, P126Q, H162Y, T163A, I180L, R200K, H228Q, I244L V5I, I10V, R22K, R104K, A138M, K176P, D195G, Y227F