Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Willliamson (2003)
Title Characterization and selection of HIV-1 subtype C isolates for use in vaccine development.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 28
NumPts 28
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CW-CTSC1 CTSC1 None None   V35T, T39E, S48T, D121H, K122E, K173T, Q174N, D177E, I178L, T200A, Q207E, V245Q, D250E, S251D, A272P, K277R, E291D, V292I, I293V  
CW-CTSC2 CTSC2 None None   V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177G, T200A, Q207E, V245E, A272S, K277R, L283I, T286A, E291D, V292I, I293V  
CW-DU115 DU115 None None  E138A V35T, E36A, T39E, S48T, K122E, D123N, T139A, I142T, T165I, Q174N, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, Q278H, K281R, T286A, E291D, V292I, I293V  
CW-DU151A DU151A None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, S162A, K173A, Q174K, D177E, T200A, Q207G, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
CW-DU151B DU151B None None   V35T, E36A, T39E, S48T, V60I, K66E, K122E, D123G, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, A360T, A376S, T377L, I382T, K390R, A400I, E404D, V435A, L452I, V466I, S468T, T470S, D471E, H483Q, G490E, L491S, K512R, S519N, K530R, V531A, A534S, N545D, A554S E29V, A267T 
CW-DU156 DU156 None None   V35T, E36A, T39E, S48T, V60I, K122P, I135V, K173A, Q174K, D177E, T200A, Q207E, V245Q, S251D, A272P, K277R, T286A, E291D, V292I, I293V  
CW-DU172 DU172 None None   T27S, V35T, T39E, S48T, V148G, A158S, K173A, Q174K, G196M, T200A, E204D, Q207E, R211K, V245Q, A272P, K277R, L279M, T286A, E291D, V292I, I293V L149S, I180F 
CW-DU174 DU174 None None   T27S, V35T, E36A, T39E, S48T, K122E, D123N, I135V, I142L, K173A, D177G, T200A, Q207D, R211K, V245Q, A272P, T286A, E291D, V292I  
CW-DU179 DU179 None None   V35T, E36A, T39E, S48T, V60I, K122E, K173A, D177E, T200A, Q207E, R211K, V245N, E248D, A272P, K275Q, K277R, T286A, E291D, V292I, I293V  
CW-DU204 DU204 None None   V35T, T39E, S48T, K122E, D123G, K173T, Q174K, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
CW-DU258 DU258 None None   V35T, E36A, T39E, S48T, K122E, D123S, I135V, S163R, T165A, K173A, D177E, T200A, E204K, Q207D, R211K, F214L, V245Q, T253TA, A272P, K277R, T286A, E291D, V292I, I293V M164H, A299P 
CW-DU281 DU281 None None   V35T, E36A, T39E, S48T, V60I, K104R, K122E  
CW-DU368 DU368 None None   V35P, E36A, I37F, T39D, S48T, V60I, K122E, D123G, S163R, T165V, K166R, K173A, Q174K, D177E, T200A, I202V, Q207K, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294A T139P, M164H, L301R 
CW-DU422 DU422 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, S163R, T165A, K173A, Q174K, D177E, T200A, Q207K, V245Q, A272P, T286A, E291D, V292I, I293V M164H 
CW-DU457 DU457 None None   V35T, T39E, S48T, K122E, D123G, V148G, S163R, T165A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V M164H 
CW-GG10 GG10 None None   V35K, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, G196R, T200A, Q207E, R211K, V245Q, A272P, L279M, T286A, E291D  
CW-GG3 GG3 None None   I31IM, V35T, E36A, T39D, S48T, V60I, K122E, D123N, R143RS, S162A, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V  
CW-GG4 GG4 None None  E138A V35T, T39E, S48T, N57NK, K122E, D123S, K173T, T200A, Q207E, L228Q, V245C, A272P, K277R, Q278H, T286A, E291D, V292I, I293V  
CW-GG5 GG5 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123N, K173A, D177G, T200A, Q207E, R211K, V245Q, E248D, K277R, T286A, E291D  
CW-GG6 GG6 None None   V35T, E36A, T39E, S48T, K104R, K122E, D123S, I135T, S162A, K166R, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248N, A272S, K277R, E291D, V292I, I293V  
CW-RB13 RB13 None None   V35T, E36A, T39E, S48T, K104R, K122E, D123S, I135T, S162C, K166R, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, I293V  
CW-RB14 RB14 None None   A33V, V35T, E36A, T39E, S48T, K122E, D123G, S162A, K166R, K173T, D177E, T200A, I202V, Q207E, V245Q, A272P, T286A, E291D, V292I K30Q, K32S 
CW-RB15 RB15 None None   T27S, V35T, T39E, S48T, K122E, D123S, I135T, I142T, K166R, K173T, D177E, G196K, T200A, Q207A, R211K, V245Q, A272P, K277R, Q278H, E291D, V292I, I293V  
CW-RB18 RB18 None None   V35T, E36A, T39E, S48T, K122E, D123G, S162A, K173T, D177E, T200A, I202V, Q207E, V245K, A272P, T286A, E291D, V292I  
CW-RB21 RB21 None None   V35T, T39K, S48T, K122E, D123G, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V R125RS 
CW-RB22 RB22 None None   V35T, E36A, T39E, S48T, V118I, D121Y, K122E, D123X, Y144F, K173A, D177E, I178L, T200A, K201R, E204K, Q207E, V245Q, D250E, A272P, Q278R, L279M, T286A, E291D, I293V I135F 
CW-RB27 RB27 None None   V35T, E36A, T39D, S48T, K122E, D123G, K166R, K173T, T200A, E204K, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I  
CW-RB28 RB28 None None   V35T, E36A, T39E, S48T, V60I, I135V, I142V, K166R, K173A, Q174K, D177E, T200A, Q207A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V T27R, K32*LS