Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Huang (2003)
Title Sequence characterization of the protease and partial reverse transcriptase proteins of the NED panel, an international HIV type 1 subtype reference and standards panel.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 42
NumPts 42
Subtype B, CRF01_AE, C, F, CRF02_AG, D, A, G, CRF06_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
42368 42368 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173V, Q174K, D177E, I178M, Q207A, R211S, V245E, K249Q, T286A, E291D, V292I, I293V  
93US141 93US141 None None T215F  R83K, K104R, D123G, S162H, D177E, R211K, A272P, K277R  
93US143 93US143 None None T215Y, K219Q  I50V, D121H, K122E, D177E, I178L, R211K, A272P, K277R  
93US144 93US144 None None   R83K, D123E, A272P, K277R, K281R, I293V  
BCFDioum BCFDioum None None   V35T, K122E, D123N, S162C, K166Q, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V  
BCFKITA BCFKITA None None   P4S, E6D, K20R, V35T, V60I, K122E, D123G, I142T, A158S, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250E, A272P, E291D, V292I, I293V  
BCIR07 BCIR07 None None   V35T, T39A, E40D, D123E, I135L, S162FY, K173T, Q174R, V179I, I195L, T200A, Q207T, R211K, V245Q, E248N, A272P, T286V, E291D, V292I, I293V, P294T  
BCIR08 BCIR08 None None   V35T, T39A, E40D, D123E, I135L, S162Y, K173T, Q174K, P176Q, E194K, I195L, G196E, T200A, Q207A, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T  
BK132 BK132 None None   K103KQ, I135T, S162C, D192DN, A272P, I293V, E297K  
BZ126 BZ126 None None   V35T, I135V, S162C, E169D, K173T, Q174K, I178L, I202V, Q207E, R211K, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V  
BZ162 BZ162 None None   V35T, T39TIM, K49R, I135V, S162C, K173T, Q174K, V179VG, Q207A, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V I167N, E169S 
BZ163 BZ163 None None   V35T, T69TA, K122E, I135V, S162C, E169D, K173T, Q174K, I178L, I202V, E203K, Q207E, R211K, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V  
BZ167 BZ167 None None   K122E, I178IM, I293V  
CM235 CM235 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, K277R, T286A, E291D, V292I, I293V P157PR 
CM237 CM237 None None   V35I, K122E, Q207QH, A272P, K277R  
CM238 CM238 None None   E6D, K11T, V35T, T39K, K43E, S105SA, K122E, D123S, K173I, Q174K, D177E, I178M, E194Q, Q207A, R211S, K238R, V245E, I274V, T286A, E291D, V292I, I293V  
CM240 CM240 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V V10S 
CM243 CM243 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, E291D, V292I, I293V  
DJ258 DJ258 None None   V35T, E36D, K104R, I135V, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, V245Q, Y271F, T286A, E291D, V292I, I293V  
DJ259 DJ259 None None   V35T, T39E, A98S, K122E, D123S, A158S, K173A, D177E, Q207E, V245Q, E248N, A272P, K277R, R284RK, T286A, E291D, V292I, I293V E169E* 
DJ263 DJ263 None None   V35T, I135T, S162A, P170H, F171Y, K173I, Q174K, D177E, G196E, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V  
ETH2220 ETH2220 None None   V35T, E36A, T39E, K43KQ, K49KR, I50IV, K122E, D123G, I135T, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294T  
HH8793 HH8793 None None   V35T, K43R, V60I, K64R, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200A, E203EK, Q207EG, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
ID12 ID12 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V  
ID17 ID17 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, T165I, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V  
NP03 NP03 None None   E6D, K11T, V35T, T39K, K43E, V60VI, K122E, D123S, I142IT, K173I, Q174K, D177E, I178M, T200I, Q207AT, R211S, K238R, V245E, T286A, E291D, V292I, I293V  
NP1465 NP1465 None None   E6D, V35T, T39K, K43E, K122E, D123S, S162C, K173IT, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, K277KR, T286A, E291D, V292I, I293V  
POC30506 POC30506 None None   E6D, K11T, P25PA, V35T, T39K, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V  
POC44951 POC44951 None None   E6K, V35T, E36D, T39A, K102E, K122E, S162A, K173T, Q174K, D177E, I178M, T200A, E204Q, Q207D, R211K, V245Q, K275R, T286A, E291D, V292I, I293V, P294T  
SE364 SE364 None None   V35T, E36A, T39E, S48T, K122E, D123G, A158S, K173A, Q174QL, D177E, I178IV, G196M, T200A, I202V, E204K, Q207E, R211K, V245Q, E248D, D250E, L260I, A272P, K277R, T286A, E291D, I293V  
SE365 SE365 None None   V8I, V35T, V60I, D121H, K122E, I135T, K173N, Q174K, D177E, T200A, Q207E, I244V, V245E, D250E, Q278E, T286A, V292I, I293V  
SM145 SM145 None None   V35T, E36A, T39E, S48T, K122E, D123G, I135T, S162C, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
UG268 UG268 None None   V35T, E36A, T39E, E40D, K49R, A98AS, D123E, T139A, A158S, K173T, D177E, T200A, Q207E, R211RK, V245Q, A272P, E291D, V292I, I293V, P294T  
UG270 UG270 None None   E6D, V8I, K32Q, V35T, T39L, K49R, V60I, K122E, D123N, I135K, D177E, I178M, T200I, Q207E, R211K, V245K, L246LP, D250E, A272P, K277R, L282C, L283I, T286A  
UG273 UG273 None None   E6D, K11T, V35T, V60I, D121H, K122E, D123S, K173A, Q174K, D177E, V179I, Q207D, R211RK, V245Q, D250E, A272P, T286A, E291D, V292I, I293V  
UG274 UG274 None None   V35T, K49R, V60I, D121Y, K122E, Q151K, I159V, T165I, D177E, I178M, T200I, Q207G, R211K, V245E, D250E, A272P, K277R, L282C, T286A, I293V P150H, G152D 
UG275 UG275 None None   K11T, K20R, V21I, V35T, T39R, K122E, D123N, T165I, K173S, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, V292I, I293V, P294T  
US1 US1 None None   R83K, K122E, S162C, I178L, T200I, A272P, K277R  
US2 US2 None None   R83K, R172RK, R211K, V245A  
US3 US3 None None   V35T, V245M, K277R, I293V  
US4 US4 None None   D123E, G196E, Q207G, V245K, K277KR, T286A, I293V  
ZAM18 ZAM18 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V