Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kagan (2005)
Title Structural analysis of an HIV-1 protease I47A mutant resistant to the protease inhibitor lopinavir.
Citation Protein Sci
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 5
NumPts 5
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
164917 164917 PI  V32I, I47A, L90M L10F, K20T T12P, K14R, I15V, G16E, E34Q, I62V, L63H, A71T, V77I, I93L  
165220 165220 PI  M46L, I47A  T12P, I13V, N37D, R57K, L63P, A71T, V82I  
166701 166701 PI  V32I, I47A, L90M  K20R, E35D, M36I, N37D, I62V, L63P, A71AT, I93L  
175236 175236 PI  V32I, I47A, L90M L33F, G73A I13V, R41K, K43R, K45R, L63P, A71T, V77I, I93L  
175848 175848 PI  V32I, M46I, I47A, L90M L10F, K20T, L89V T4A, I13V, L33V, I62V, L63P, H69Y, A71V, I93L