Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Brindeiro (2002)
Title Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy.
Citation J Clin Microbiol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 52
NumPts 52
Subtype B, F, CRF12_BF, D, C, CRF45_cpx

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
TVGG1 TVGG1 RTV 95 I54V, V82L L24I K20R, E35D, M36I, R41K, I62V, L63P, I64V  
TVGG11 TVGG11 None    M36I, I62V, L63P  
TVGG12 TVGG12 RTV, NFV 87 M46I, I54V, V82A  L10I, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, D60E, Q61D, K70R, I72V, T74A, L89M  
TVGG13 TVGG13 None    I15V, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63S, L89M  
TVGG14 TVGG14 None    T12P, M36I, N37S, R41K, L63P, I64V, I93L  
TVGG15 TVGG15 None    I13V, G16A, R41K, V77I  
TVGG17 TVGG17 None    L10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, E65D, I72T, L89M  
TVGG18 TVGG18 None    L10I, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63T, I93L  
TVGG19 TVGG19 None    L10V, Q18E, E35D, L63P, I93L  
TVGG2 TVGG2 None    R41K, L63P, I64V, E65D, I72V  
TVGG20 TVGG20 None    I62V, L63P, V77I, I93L I47T 
TVGG21 TVGG21 RTV 65 I54V, V82A Q58E L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, E65D  
TVGG22 TVGG22 None    G17E, I62V, L63P, E65D, V77I  
TVGG23 TVGG23 None    L10V, L63P, I72E, V77I, I93L  
TVGG24 TVGG24 None    Q18R, N37C, R41I, I47M, L63P, I72K, V77I, I93L M46K 
TVGG27 TVGG27 RTV, NFV 30 I54V, V82A, L90M  L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I  
TVGG28 TVGG28 IDV 34 M46I, I54V, V82M, L90M Q58E I15V, L63P  
TVGG3 TVGG3 NFV 30 I54IV, V82VA  L10LV, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89M  
TVGG30 TVGG30 RTV, NFV 118 M46L, I54V, V82A, L90M  L10I, I15V, N37D, L63P, C67W, A71V  
TVGG33 TVGG33 None    L63P, H69Q, V77I  
TVGG34 TVGG34 None    L10V, N37S  
TVGG35 TVGG35 None    K14R, I62V, L63P, H69Q  
TVGG37 TVGG37 None    T12P, L19I, L63P, C67D, V77I, Q92K  
TVGG38 TVGG38 RTV, IDV, Unknown, NFV 66 M46L, I54V, V82A L10F I15V, L63P, L89I I50F 
TVGG39 TVGG39 None    L19I, N37S  
TVGG4 TVGG4 IDV 61 I54V, V82A L10F I3V, R41K, D60E, I62V, L63P, V77I, I93L  
TVGG41 TVGG41 None    I15V, M36I, N37K, R41N, R57G, D60E, L63P, H69K, L89M, I93L  
TVGG42 TVGG42 None    N37S, I62V, L63P  
TVGG5 TVGG5 IDV 113 M46L, I54V, V82A L24I R41K, L63P, I64V  
TVGG7 TVGG7 None    L10I, I13V, K14R, I15V, G16E, M36I, L63V, H69K, L89M, I93L  
TVGG8 TVGG8 None    G17D, E35D, D60E, L63P  
TVSP09 TVSP09 RTV 30   I15V, E35D, M36I, N37D, R41K, R57K, I64V, E65D  
TVSP1 TVSP1 RTV, NFV 47 I54V, V82A  T12A, Q18L, L19I, K20R, E35D, M36I, R41K, R57K, Q61H, L63P, I72T  
TVSP10 TVSP10 RTV 13   N37E, L63A, I72V, V77I  
TVSP11 TVSP11 NFV 32 D30N  E35D, R41K, L63P, A71V, V77I, I93L  
TVSP12 TVSP12 RTV 55   R8Q, I13V, E35D, M36I, R41K, Q61N, I62V, L63H, H69Q  
TVSP14 TVSP14 RTV, NFV 83 V82A  N37S, R41K, L63P  
TVSP15 TVSP15 RTV, NFV 92 V82L L24I, K43T L10I, E35D, M36I, R41K, R57K, Q61N, L89M  
TVSP16 TVSP16 RTV 84 I54V, V82A Q58E L10V, T12N, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63Q, E65D  
TVSP17 TVSP17 RTV, NFV 94 I54V, V82A, L90M  R41K, L63P, A71V  
TVSP18 TVSP18 RTV 104 I54V  L10I, I15V, K20R, E35D, M36I, R41K, Q61D, L63P, I72V R57E 
TVSP19 TVSP19 NFV 41 D30N  I13V, I15V, L19I, E35D, M36I, R41K, R57K, D60E, L63P, I72V  
TVSP2 TVSP2 RTV, NFV 83 I54V, V82A  L10I, K20R, E35Q, M36I, N37D, R41K, D60E, L63P, A71V, I72V  
TVSP21 TVSP21 RTV, IDV, NFV 91   I15V, E35D, M36I, R41K, Q61N, K70R, I72T, L89M  
   NFV 34   E35D, M36I, R41K, R57K, Q61N  
TVSP22 TVSP22 Unknown, RTV, IDV, NFV 81   I15V, E35D, M36I, R41K, Q61N, K70R, I72T, L89M  
TVSP24 TVSP24 RTV, NFV, Unknown   Q18L, N37E, R57K, L63P, V77I, I93L G17S 
TVSP3 TVSP3 Unknown, RTV 60   T12K, I15V, E35D, N37E, K43R, V82I  
TVSP4 TVSP4 NFV 15 M46I  T12S, I13V, E35D, M36I, R41K, R57G, L63P, I64V, A71T Q61P 
TVSP5 TVSP5 RTV 65 I54V, V82A  I15V, K20R, E35D, M36I, N37E, L63P, H69K, A71V  
TVSP6 TVSP6 Unknown, RTV, NFV 63 I54V, V82A  L10V, T12K, I15V, L19I, K20R, E35D, M36I, N37D, R57K, A71V  
TVSP7 TVSP7 RTV, NFV 34 D30N N88D T12A, I13V, L19I, M36I, R41K, K43R, L63P, A71V, I93L