Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Carr (2001)
Title Diverse BF recombinants have spread widely since the introduction of HIV-1 into South America.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 21
NumPts 21
Subtype B, CRF12_BF, B + F, CRF17_BF

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ARCH003 ARCH003 None None   V35T, D123E, I135V, D177N, I202V, L228H, P243A, V245M, I293V, P294T, E297R, K311R, I329V, G359S, A371V, T377L, S379G, T386I, A400T, E404D, K431T, S468P, H483Y, Q524E  
ARCH014 ARCH014 None None   V35T, I135V, T165I, V245M, A272P, K277R, I293V, A376T, T386I, K390R, A400T, T403I, L452K, S468P, K530R, A554T  
ARCH054 ARCH054 None None K70R  S3C, V35I, K46R, R83K, K166R, Q207A, R211K, A272P, I293V, S322T, K366R, A376T, K390R, A400T, L452S, D460N, K476Q, S519N  
ARMA006 ARMA006 None None   V35T, T39A, D123E, I142V, K166R, R211K, A272P, K277R, K281R, T286A, E297K, G333E, Q334H, K366R, A376T, T377L, K390R, E399D, A400T, K431T, V435A, E449D, D460N, R461K, T470N, H483L, E492K, S519N, A534S, V559I  
ARMA029 ARMA029 None None   V35T, T39K, K122E, I135V, E204G, V245L, E248D, A272P, K281R, I293V, E297K, Q334Y, K390R, Q394L, E399D, A400T, V417I, K431T, V435A, A446S, L452K, V466A, D471E, T477A, Q480H, L491S, S519N, A534S, V559I  
ARMA036 ARMA036 None None   V35T, D123E, T165I, I202V, D250E, A272P, K281R, T286A, I293V, E297K, A376T, T386I, Q394L, E399D, A400T, K431P, V435A, G436E, A446S, L452K, V466A, D471E, T477A, Q480H, H483Q, L491S, S519N, A534S, V559I  
ARMA037 ARMA037 None None   V35T, K49R, D123E, I202V, A272P, K277R, T286A, E297K, S322L, A360T, A376T, K385R, T386I, Q394L, E399D, A400T, K431P, V435A, G436E, A446S, L452K, V466T, D471E, T477A, Q480H, H483Q, L491S, S519N, A534S, V559I  
ARMA038 ARMA038 None None   D123E, I178L, R211K, F214L, V245I, A272P, V292I, I293V, E297K, K390R, Q394L, E399D, A400T, K431T, V435A, G436E, A446S, L452K, V466A, D471E, T477A, Q480H, H483K, L491S, L517I, S519N, A534S, V559I  
ARMA062 ARMA062 None None M184I V106I, M230I E6D, G51R, W88*, V118I, D123E, I135T, W153*, S162N, F171Y, G190R, T200E, W212*, F214L, W239*, V245M, W252*, G262R, W266*, A272P, K277R, R284K, I293V, G316E, W383*, T386I, W398*, W401*, W402*, T403V, W410*, W414*, W426*, V442I, R448K, L452K, G453R, G462R, S468P, Q480H, H483N, G504R, W535*, G541R, G543R, G544R, A554T, G555R G18R, G45K, G273E, G444K 
ARMA070 ARMA070 None None  M230I M16I, K32E, V35T, E36A, R78K, W88*, G93R, I135T, G155R, G196E, E204D, L210F, W212*, A272P, K277R, K281R, P294S, E297K, R307K, G316R, D324E, A327V, W383*, K390R, W398*, W410*, W414*, W426*, V435A, D460N, R461K, S519N, W535*, G555R G18S, E28V, G444R 
ARMA097 ARMA097 None None   V35T, E36D, T39I, V60I, K122E, I135V, D250E, A272P, T286P, I293V, E297T, I329L, Q394L, E399D, A400T, K431T, V435A, A446S, L452Q, R461K, V466A, D471E, T477A, Q480H, H483Q, L491P, L517I, S519N, K527R, K530R, A534S, V559I  
ARMA132 ARMA132 None None  V106I F214L, Y271F, A272P, K277R, I293V, Q334E, P345Q, R356K, A360T, A376V, T386I, K390R, A400T, Q524L, V559I  
ARMA159 ARMA159 None None   V35T, K122E, D123A, S134C, I135V, I142T, A272P, K281R, E297K, I329V, Y342F, Q394L, E399D, A400T, K431T, V435A, G436E, A446S, R448K, L452K, R461K, D471E, T477A, Q480H, H483Y, L491S, A534S, I556V, V559I  
ARMA173 ARMA173 None None M184I M230I G15R, M16I, K22R, G45R, G51R, W71*, W88*, V118I, I135T, G141E, R211K, W212*, F214L, W252*, W266*, A272P, K277R, E297A, V314I, I326V, G333R, Q334Y, W337*, A360T, A376S, W383*, W398*, W402*, E404K, W410*, W414*, W426*, K431T, G436R, R448K, G453R, I506L, Q509T, L517I, W535*, G543R, A554S, G555R, R557K G18S, G152R, G273K, G444R 
ARMA185 ARMA185 None None   V35T, W88*, K122E, G196R, Q197P, R211K, W212*, W229*, V245M, A272P, K281R, I293V, E297K, G316R, S322T, G352R, M357T, R358K, I375V, A376T, S379C, V381I, W383*, K390R, Q394L, W398*, E399D, A400T, W402*, W410*, W414*, K431T, V435A, L452Q, G453R, V466A, V467A, S468P, D471E, T477A, Q480H, H483Q, G490R, L491P, K512Q, S519N, A534S, W535*, G544R, G555R G213R, G444R 
ARMS008 ARMS008 None None   V21I, Q174H, I178M, Q207E, R211K, V245M, A272P, I293V, I326V, I329V, G333D, Q334N, T386V, T403M, L452I, S468P, T470K, S519N  
BOL122 BOL122 None None   K101R, K122E, I135T, S162C, R211K, F214L, E248H, A272P, I329L, Q334E, Y342F, E344D, M357A, R358K, V365I, A400T, E432D, V435E, A437V, D460N, H483Y, L491P, K512R, L517I, I556V  
BOL137 BOL137 None None   K102R, I135V, I178M, R211K, A272P, K281R, E297K, K311R, S322T, A371V, A376T, K390R, Q394L, E399D, A400T, K431T, V435T, A446S, L452K, R461K, D471E, T477A, Q480H, H483Q, L491S, E492Q, K512R, S519N, A534S, V559I  
URTR17 URTR17 None None   V35T, I135V, S162C, E204D, V245E, A272P, I274V, K277R, K281R, V292I, E297K, P321S, Q334H, G359S, A376T, K385R, K390R, E399D, A400T, E413D, K431T, V435A, A446S, L452K, V466A, T470A, D471E, T477A, Q480H, H483Q, L491P, S519N, V531I, A534S, V559I  
URTR23 URTR23 None None   V35T, T39M, D123E, I135V, Q197K, F214L, E248D, L260V, A272P, I274V, T286A, E297K, A376T, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452I, V466A, S468P, D471E, T477A, H483Q, L491S, S519N, A534S, V559I  
URTR35 URTR35 None None   V35T, V60I, I135V, I142V, R211A, A272P, E297K, Q334L, K366R, A376T, K390R, Q394L, E399D, A400T, K431T, V435A, N447S, L452K, R463K, V466A, S468P, D471E, T477A, Q480H, H483Q, L491S, L503I, S519N, A534S, V559I