<!--#set var="title" value="Isolate Data" --> <!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SNA3-250 SNA3-250 Senegal 2008 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 NVP|NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   V106A F227L Q23QH, V35T, K49R, S68G, V90I, K122E, D123E, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, D250DE  
>SNA3-250| codons 1-250
PISPIETVPVKLKPGMDGPKVKHWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSATVLDVGDAYFSVPL
DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTRNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, M36I, N37D, R41K, I64L, H69K, L89M  
>SNA3-250| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QILLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Kebe, K High rate of antiretroviral drug resistance mutations in HIV type 1 infected Senegalese children in virological failure on first-line treatment according to the World Health Organization guidelines. ARHR, 2013