Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 13472A | 13472A | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NNRTI|NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, N88G, L90M | K20T | I15V, L19I, E35D, M36I, R41K, R57RK, Q61E, I62V, L63P, A71IT, I72IT |
| >13472A| codons 1-99 PQITLWQRPLVTIKVGGQITEALLDTGADDTVLEDINLPGKWKPKIVGGIGGFIKVKQYD EVPIEICGHKTTGTVLVGPTPVNIIGRGLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | T69D | G190GRS | K20R, K43Q, E44D, K101KQ, V118I, K122E, K166R, V179VI, G196GE, T200A, E203X, Q207E, H208X, R211K, V245E, E248Q, D250E, K277R, Q278H, I293V, K347KQ, A360T, K366R, T369V, A376T, K390KR, A400T |
| >13472A| codons 1-400 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII YQYVDDLYVSSDLEIEQHRAKIVELREYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPQKESWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFQNLKTGKYARMRGT HTNDVRQLVEAVQKITTESIVIWGKTPKFRLPIQKETWET |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |