Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

CAI Mutation Pattern & Susceptibility

12 patterns of major drug resistance mutations (defined here) from 25291 clinical isolates obtained from 23759 persons infected with HIV-1 Group M virus are arranged in decreasing prevalence in the table (updated on 2025-9-10). Sequences containing a mixture at one of the major drug resistance positions were excluded from the table. For each pattern, drug susceptibility data on isolates matching the specific mutation pattern is shown on the left side.

The number of sequences with each pattern is indicated, as well as the median fold resistance, as assayed by the ViroLogic PhenoSense assay, to each of several individual members of the selected drug class. Subscripts indicate the number of sequences assayed for resistance to the designated drug. Data is also available for download in a tab-delimited format. Interquartile ranges are available by clicking here. Data on the 30 most common mutation patterns is also available in a PDF format.

Mutation PatternsLEN
foldn
66I279716
66I,67H,74D27972
66I,74D14285
70N,74K2891
67K,70H2552
56I2222
70H1543
70N241
74D174
67H1521
None1.212
74S 
67K