Sequence information can be entered in FASTA, plain text, or GRF (Bayer Diagnostics) format. Sequences in FASTA format or plain text can be pasted in the text box (option A) or uploaded (option B). GRF files can only be uploaded (option C). Using options A or B, it is possible to analyze up to 100 sequences at a time (character limit:600,000). Example data sets: a smaller set and 37 sequences from Margeridon-Thermet (2009)