Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Multi-Drug Resistant Panels

Viruses emerging during ART are experiments of nature that provide insight into viral escape from ARV suppression. Although no two HIV-1 strains are identical, drug-resistant variants often share mutational patterns. Virus clones containing common clusters of drug-resistance mutations (DRMs) make it possible to compare the activity of an ARV candidate with other licensed or investigational ARVs belonging to the same class.
NRTI Panel
A panel of 12 prototypical infectious multidrug resistant HIV-1 reverse transcriptase (RT) clones. The panel includes clones with each of the published nucleoside analog RT inhibitor (NRTI) mutations in the combinations that occur most frequently in HIV-infected individuals.

Multi-NRTI Resistant HIV-1 RT Panel

NNRTI Panel
A panel of 10 prototypical infectious multidrug resistant HIV-1 reverse transcriptase (RT) clones. The panel includes clones with each of the published non-nucleoside analog RT inhibitor (NNRTI) mutations in the combinations that occur most frequently in HIV-infected individuals.

Multi-NNRTI Resistant HIV-1 RT Panel

PI Panel
A panel of 18 prototypical infectious multidrug resistant HIV-1 protease clones. The panel includes clones with each of the published protease inhibitor (PI) mutations in the combinations that occur most frequently in HIV-infected individuals.

Multi-PI Resistant HIV-1 protease Panel

RAL Panel
A panel of 5 prototypical infectious RAL resistant HIV-1 integrase clones. The panel includes clones with RAL mutations in the combinations that occur most frequently in HIV-infected individuals.

RAL Resistant HIV-1 Integrase Panel