Protease Inhibitors (PIs) associated Drug Resistance Mutations (DRMs)
Position
MajorDRM
MinorDRM
10
FIRVY
11
I
23
I
24
I
30
N
not N
32
I
not I
33
FI
35
G
43
T
46
IL
not IL
47
VA
not VA
48
VMALSTQ
not VMALSTQ
50
VL
not VL
53
LY
54
VAMLTS
not VAMLTS
58
E
71
VTIL
73
CATS
74
P
76
V
not V
82
ATFSMLC
not IATFSMLC
83
D
84
VAC
not VAC
88
S
DGT
89
V
90
M
The table was updated on 2011-5-6. All capital letters are one-letter amino acid code; # indicates an insertion; ~ indicates a deletion. any and not are special symbols; any means any mutations; not means everything except the following mutations.