Integrase inhibitors (INIs) associated Drug Resistance Mutations (DRMs)
Position
MajorDRM
MinorDRM
51
Y
54
I
66
IAK
not IAK
68
VI
74
MR
92
QV
not QV
95
K
97
A
114
Y
121
Y
not Y
125
K
128
T
138
KA
not KA
140
SAC
not SAC
143
CHR
not CHR
145
S
not S
146
P
not P
147
G
not G
148
HKR
not HKR
151
IAL
153
Y
155
HS
not HS
163
RK
230
R
263
K
The table was updated on 2012-6-13. All capital letters are one-letter amino acid code; # indicates an insertion; ~ indicates a deletion. any and not are special symbols; any means any mutations; not means everything except the following mutations.