Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Clinical Trial Datasets

ACTG 5202 clinical trial
References
Mollan K, Daar ES, Sax PE, Balamane M, Collier AC, Fischl MA, Lalama CM, Bosch RJ, Tierney C, Katzenstein D; AIDS Clinical Trials Group Study A5202 Team. HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. J Infect Dis. 2012 Dec 15;206(12):1920-30.
Sax PE, Tierney C, Collier AC, Daar ES, Mollan K, Budhathoki C, Godfrey C, Jahed NC, Myers L, Katzenstein D, Farajallah A, Rooney JF, Ha B, Woodward WC, Feinberg J, Tashima K, Murphy RL, Fischl MA; AIDS Clinical Trials Group Study A5202 Team Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results.J Infect Dis. 2011 Oct 15;204(8):1191-201.
Daar ES, Tierney C, Fischl MA, Sax PE, Mollan K, Budhathoki C, Godfrey C, Jahed NC, Myers L, Katzenstein D, Farajallah A, Rooney JF, Pappa KA, Woodward WC, Patterson K, Bolivar H, Benson CA, Collier AC; AIDS Clinical Trials Group Study A5202 Team. Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.Ann Intern Med. 2011 Apr 5;154(7):445-56.
HIVDB
PR Data in HIVDB
RT Data in HIVDB
Sequences
Nucleotide sequences in fasta format
ACTG5202_PR_fasta.txt,   ACTG5202_RT_fasta.txt
Composite alignment (of sequences at baseline)
ACTG5202_PR_composite.html,   ACTG5202_RT_composite.html
List of sequences with stop codon, ambiguity codon and unusual residues
ACTG5202_PR_QA.txt,   ACTG5202_RT_QA.txt

Method: Direct PCR, Dideoxy terminator sequencing
Sample: Plasma
Timing: Multiple timepoints

Browse
Integrated view of ARV, genotypes, RNA and CD4 on 261 patients
Dataset
Downloadable data files
Note on Dataset
Four patients were excluded from the data set; changes are described in detail in ACTG5202Dataset.txt.