Overall statistics

1040 References
72881 Individuals
80670 Time points

148737 Isolates

147538 Clinical Isolates, 1199 Lab Isolates
148230 HIV-1 Isolates, 279 HIV-2/SIVsm,maq Isolates, 228 NHPL (Non-Human Primate Lentivirus)

158373 Sequences

76450 RT Sequences, 75236 Protease Sequences, 6687 Integrase Sequences
134884 Sequences from GenBank, 23489 Sequences not in GenBank

2291805 Mutations

1435695 RT Mutations, 749261 Protease Mutations, 106849 Integrase Mutations

46071 Phenotype results

14402 NRTI, 7966 NNRTI,22818 PI, 885 INI Phenotype results

Number of sequences according to geographical region

Continent	Regions
Africa (n = 30405)	South Africa (7634), Uganda (4145), Cameroon (3714), Nigeria (1422), Kenya (1313), Zambia (1272), Zimbabwe (895), Cote d'Ivoire (873), Tanzania (869), Botswana (809), Mali (744), Malawi (603), Ghana (565), Burkina Faso (490), Senegal (476), DRC (464), Angola (430), Mozambique (358), Ethiopia (275), Gabon (263), Benin (257), Algeria (252), Burundi (246), Central African Republic (234), CAR (185), Equatorial Guinea (165), Morocco (165), Togo (162), Rwanda (160), Chad (154), Niger (105), Africa (100), Swaziland (94), Guinea (91), Seychelles (84), Libya (68), Sudan (60), Madagascar (60), Zaire (31), Primate Center (31), Guinea-Bissau (19), Liberia (19), Gambia (18), Congo-Brazzaville (12), Dijibouti (7), Somalia (6), Sierra Leone (3), West Africa (3)
Asia (n = 17465)	China (2664), Taiwan (2616), Vietnam (2251), India (2214), Thailand (2209), Japan (1620), Cambodia (868), Israel (617), Singapore (536), Korea (468), Malaysia (459), Uzbekistan (295), Kazakhstan (189), Iran (104), Republic Of Georgia (91), Saudi Arabia (72), Afghanistan (45), Yemen (44), Myanmar (27), Lebanon (26), Indonesia (24), Turkey (14), Nepal (12)
Europe (n = 28260)	Spain (4540), Italy (3648), France (3401), Germany (2542), Portugal (2237), Sweden (1557), U.K. (1494), Denmark (1115), Russia (1070), Belgium (937), Greece (613), Estonia (556), Switzerland (537), Romania (396), Luxembourg (391), Ukraine (364), Cyprus (311), Netherlands (306), Slovenia (252), Poland (242), Republic of Latvia (234), Austria (201), Norway (194), Bulgaria (160), Greenland (150), Serbia (136), Albania (132), Finland (122), Europe (110), Ireland (88), Azerbaijan (82), Hungary (59), Yugoslavia (33), Slovakia (20), Belarus (18), Moldova (12)
North America (n = 59451)	U.S. (52797), Canada (4412), Cuba (1123), Honduras (672), Mexico (265), Trinidad (66), Puerto Rico (31), Barbados (27), Antigua (16), Saint Vincent (12), Saint Lucia (10), Grenada (8), Dominica (6), North America (3), Montserrat (2), Panama (1)
Oceania (n = 807)	Australia (807)
South America (n = 11687)	Brazil (7412), Argentina (2518), Peru (749), Venezuela (521), Chile (327), Colombia (82), Uruguay (38), Ecuador (12), Guyana (12), Suriname (10), Bolivia (6)

Number of individuals according to regimen received

NRTI component	NNRTI component	PI component	NRTI + PI or NNRTI regimen
AZT (2035) DDI (765) D4T (739) 3TC (263) ABC (222) DDC (219) TDF (32) AZT/3TC (4271) D4T/3TC (3950) DDI/D4T (1663) AZT/DDI (1557) AZT/DDC (801) DDI/3TC (233) 3TC/TDF (194) D4T/ABC (179) 3TC/ABC (161) DDI/ABC (127) AZT/D4T (85) DDC/D4T (75) DDI/TDF (71) AZT/ABC (60) DDC/3TC (60) FTC/TDF (54) D4T/TDF (30) AZT/3TC/ABC (535) AZT/DDI/3TC (226) D4T/3TC/ABC (125) DDI/D4T/3TC (102) DDI/D4T/ABC (89) 3TC/ABC/TDF (86) AZT/DDC/3TC (72) AZT/D4T/3TC (57) DDI/3TC/TDF (45) AZT/3TC/TDF (38) D4T/3TC/TDF (31) AZT/DDI/DDC (29) DDI/3TC/ABC (24) AZT/DDI/D4T/3TC (31) AZT/3TC/ABC/TDF (31)	NVP (4078) EFV (2853) DLV (191) ETR (10)	NFV (2335) IDV (2212) SQV (934) SQVr (744) LPVr (646) RTV (574) IDVr (369) APV (213) APVr (121) ATV (66) ATVr (55) DRVr (43) NFV/SQV (212) APV/LPVr (53) IDV/SQV (51) NFV/IDV (45) NFV/RTV (27)	D4T/3TC/NVP (1337) AZT/3TC/IDV (949) AZT/3TC/EFV (776) D4T/3TC/EFV (699) D4T/3TC/IDV (693) AZT/3TC/NVP (661) AZT/3TC/NFV (620) D4T/3TC/NFV (618) AZT/3TC/SQV (347) DDI/D4T/NFV (341) DDI/D4T/EFV (288) DDI/D4T/NVP (219) D4T/3TC/SQV (199) AZT/3TC/RTV (190) D4T/3TC/SQVr (168) D4T/3TC/RTV (150) DDI/D4T/IDV (139) AZT/3TC/SQVr (122) DDI/D4T/SQVr (120) AZT/DDC/SQV (112) D4T/NFV/NVP (104) AZT/3TC/ABC/EFV (101) AZT/3TC/LPVr (98) AZT/3TC/IDVr (95) D4T/3TC/LPVr (78) D4T/3TC/IDVr (72) DDI/D4T/NFV/EFV (69) D4T/3TC/NFV/NVP (68) AZT/DDI/NVP (68) 3TC/TDF/EFV (59) AZT/DDI/NFV (58) AZT/DDI/IDV (56) AZT/DDI/SQV (53) DDI/D4T/SQV (52) 3TC/TDF/NVP (52)

Number of individuals according to subtype and drug-class experienced

Subtype	protease		RT		integrase
Subtype	PI-naive	PI-treated	RTI-naive	RTI-treated	INI-naive	INI-treated
B	16671	8202	13755	19825	2224	106
A	3109	184	2516	720	193	1
C	7043	446	6366	3337	812	1
D	1275	125	1007	444	132
F	831	617	452	483	182
G	1131	254	958	1065	104
CRF01_AE	2845	108	2453	1853	369
CRF02_AG	3302	145	2400	788	471	2
Other	705	109	1101	544	83