The World Health Organization 2009 List of Mutations

For Surveillance of Transmitted Drug Resistant HIV Strains

NRTI
M41L
K65R
D67N, G, E
T69D, Ins
K70R, E
L74V, I
V75M, T, A, S
F77L
Y115F
F116Y
Q151M
M184V, I
L210W
T215Y, F, I, S, C, D, V, E
K219Q, E, N, R
NNRTI
L100I
K101E, P
K103N, S
V106M, A
V179F
Y181C, I, V
Y188L, H, C
G190A, S, E
P225H
M230L
PI
L23I
L24I
D30N
V32I
M46I, L
I47V, A
G48V, M
I50V, L
F53L, Y
I54V, L, M, A, T, S
G73S, T, C, A
L76V
V82A, T, F, S, C, M, L
N83D
I84V, A, C
I85V
N88D, S
L90M

(New mutations are in bold.)

from Drug Resistance Mutations for Surveillance of Transmitted HIV-1 Drug-Resistance: 2009 Update, Authors: Diane E. Bennett1, Ricardo J. Camacho2, Dan Otelea3, Daniel R. Kuritzkes4, Hervé Fleury5, Mark Kiuchi6, Walid Heneine7, Rami Kantor8, Michael R. Jordan9, Jonathan M. Schapiro6, Anne-Mieke Vandamme10, Paul Sandstrom11, Charles A.B. Boucher12,13, David van de Vijver11, Soo-Yon Rhee6, Tommy F Liu6, Deenan Pillay14, Robert W. Shafer6

  1. World Health Organization, Geneva, Switzerland;
  2. Molecular Biology Laboratory, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal;
  3. Molecular Diagnostics, "Prof. Dr. Matei Bals" Institute for Infectious Diseases, Bucharest, Romania;
  4. Brigham and Women's Hospital Harvard Medical School, Boston MA, USA;
  5. Laboratoire de Virologie EA 2968, Université de Bordeaux, France;
  6. Division of Infectious Diseases, Stanford University, Stanford, CA;
  7. Centers for Disease Control and Prevention, Atlanta, GA, USA;
  8. Division of Infectious Diseases, Brown University, RI, USA;
  9. Tufts University School of Medicine, Boston, MA, USA;
  10. Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium;
  11. Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottowa, Ontario, Canada;
  12. Department of Virology, Erasmus MC, University Medical Center Rotterdam, The Netherlands;
  13. Department of Medical Microbiology. University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands;
  14. Centre for Virology, Division of Infection and Immunity, University College London and Centre for Infections, Health Protection Agency, London UK.