Sierra version 2.2.5-1 (last updated 2018-04-23)
HIVdb version 8.5 (last updated 2018-04-16)

INSTI Resistance Mutation Scores

(PI · NRTI · NNRTI)
RuleBICDTGEVGRAL
H51Y551515
T66A006015
T66I006015
T66K15156060
E92G003015
E92Q10106030
E92V006030
Q95K001010
T97A001010
G118R15153030
F121Y10106060
E138A10101515
E138K10101515
E138T10101515
G140A10103030
G140C10103030
G140S10103030
Y143A551060
Y143C551060
Y143G551060
Y143H551060
Y143K551060
Y143R551060
Y143S551060
P145S00600
Q146P00600
S147G00600
Q148H25256060
Q148K30306060
Q148N001510
Q148R25256060
V151A003015
V151L15156030
S153F1515150
S153Y1515150
N155H10106060
N155S003030
N155T003030
E157Q001010
G163K001515
G163R001515
S230R001515
R263K15153015
Combination RuleBICDTGEVGRAL
E138AKT + G140ACS10101515
E138AKT + Q148HKR101000
G140ACS + Q148HKR101000
Y143ACGHRS + G163R5550
Y143ACGHRS + S230R5550
Q148HKR + N155H5500
Q148HKR + G163KR5500
E157Q + R263K101000
H51Y + R263K1010150
L74IM + Y143ACGHRS5550
L74IM + Q148HKR5500
E92Q + N155H5500
T97A + Y143ACGHRS0050
T97A + Q148HKR5500