<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Oliveira (2018)
Title Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir.
Citation Retrovirology
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 38
NumPts 20
Subtype B, CRF02_AG, D, CRF01_AE, C

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
E78001 E78001 None   L68LV V31I, I73IV, T112TI, I113V, T124A, I162IV, V201I R284RG 
E78003 E78003 None    E11D, S24N, V31VI, V32I, L45LI, L101I, T112A, S119X, T122TI, T124TA, K136KN, V201VI  
E78004 E78004 None    E10EA, E11D, V37I, I72V, K111A, T112A, S119P, T125A, V201VI, T206S, I208IL  
  E78004_Wk18_CAB Unknown  Q148R Q95QK E10EA, E11D, V37I, K111A, T112A, S119P, T125A, V201VI, T206S, I208IL  
  E78004_Wk26_CAB Unknown  E138EK, Q148R Q95QK E10EA, E11D, V37I, K111A, T112A, S119P, T125A, V201VI, T206S, I208IL  
  E78004_Wk36_CAB Unknown  E138K, G140GS, Q148R  E10EA, E11D, V37I, L74I, K111A, T112A, S119P, T125A, V201VI, T206S, I208IL  
  E78004_Wk18_EVG Unknown  T66I Q95K E10EA, E11D, V37I, K111A, T112A, S119P, T125A, E157EQ, V201VI, T206S, I208IL  
  E78004_Wk26_EVG Unknown  T66I Q95K E10EA, E11D, V37I, K111A, T112A, S119P, T125A, E157Q, V201VI, T206S, I208IL  
  E78004_Wk36_EVG Unknown  T66I Q95K, S230R E10EA, E11D, V37I, K111A, T112A, S119P, T125A, E157Q, V201VI, T206S, I208IL  
E78005 E78005 None    L101I, I203M, T206TS  
E78060 E78060 None   A128AT E10D, L45V, L74I, L101I, S119G  
  E78060_Wk36_RAL Unknown   T97A, A128AT, V151I L45V, L74I, L101I, S119G, E157Q  
E78110 E78110 None    E11D, V31I, I72V, A91AT, L101I, S119T, K156N, E157Q, F181L, V201I, K211R, A265AV, I268IL  
Pt1 E102952 DTG    S17N, K34KR, L45I, L101I, T112X, T124A, T125A, E157Q, K160E, D167E, G193E, V201I, I220V, L234I D288N 
  E102952_Wk18_RAL DTG, Unknown  Q148R  S17N, K34KR, L45I, L101I, T112X, T125A, E157Q, K160E, D167E, G193E, V201I, I220V, L234I D288N 
  E102952_Wk38_RAL DTG, Unknown  E138K, G140A, Q148R V151VI S17N, K34KR, L45I, L101I, T112X, T125A, E157Q, K160E, D167E, G193E, V201I, I220V, L234I D288N 
Pt10249 Isol10249 None    V31I, L45Q, I72V, L101I, K111E, I113V, D207N, L234I  
Pt10387 Isol10387 None    V31I, L45Q, I72V, K111E, I113V, T125A, M154I, V201I, D207N, L234I  
Pt10947 Isol10947 None    D6E, E10D, D25E, V31I, L45Q, M50I, P90S, T93S, F100Y, L101I, G106A, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, R269K, D278A S283G, D288N 
Pt14514 Isol14514 None    K7R, S17N, M50I, I72V, K111Q, T112V, T124A, T125V, I220L, Y227F, D256E  
Pt14515 Isol14515 None    E11D, R20K, A21T, V31I, L101I, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, V249I S283G 
Pt14624 Isol14624 None    S17N, A23V, L28I, S39C, L101I, T124A, K244KR  
Pt14637 Isol14637 None    E11D, R20K, V31I, S39N, M50I, S119T, T124N, G193E, V201I D286N 
Pt14947 Isol14947 None    E11D, R20K, V31I, S39N, M50I, I72V, S119T, T124N, G193E, V201I, T218TS D286N 
Pt2 E103212 None    S17N, V31I, L101I, K111R, T112A, S119SR, T122TI, S123SC, T124TN, T125TA, E157Q, K160Q, V201I, K215N, D256E  
Pt4742 Isol4742 None    V31I, S39C, I84M, Q95P, F100Y, L101I, T112V, T124N, T125A, D167E, V201I, I203M, K215N, T218L, L234I, D278A S283G, R284G 
Pt5326 Isol5326 None    K7R, E11D, K14R, V31I, V32I, M50L, L101I, T124N, S195T, I203M, I220L, Y227F  
  Pt5326_Wk45_EVG Unknown  R263K  K7R, E11D, K14R, V31I, V32I, M50L, L101I, T124N, S153A, S195T, I203M, I220L, Y227F  
  Pt5326_Wk17_CAB Unknown  Q148K  K7R, E11D, K14R, V31I, V32I, M50L, L101I, T124N, S195T, I203M, I220L, Y227F  
  Pt5326_Wk28_CAB Unknown  G140S, S147SG, Q148K  K7R, E11D, K14R, V31I, V32I, M50L, L101I, T124N, S195T, I203M, I220L, Y227F  
  Pt5326_Wk48_CAB Unknown  G140S, S147G, Q148K L74M K7R, E11D, K14R, V31I, V32I, M50L, L101I, T124N, S195T, I203M, I220L, Y227F  
Pt6343 Isol6343 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I S283G 
  Pt6343_Wk46_CAB Unknown   S153Y, G163R K14R, A21T, V31I, S39N, T112V, T125A, G134N, I135V, K136R, D167E, V201I, L234I S283G 
Pt96USSN20 96USSN20 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K S283G 
  Pt96USSN20_Wk2_ EVG Unknown  T66I, S147G T97A K14R, V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K S283G 
  Pt96USSN20_Wk17_CAB Unknown  E138EK, Q148R, R263RK  K14R, V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K S283G 
  Pt96USSN20_Wk27_CAB Unknown  E138K, Q148R, R263K L74LM K14R, V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K S283G 
  Pt96USSN20_Wk45_CAB Unknown  E138K, Q148R, R263K L74M K14R, V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K S283G