Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Varghese (2016)
Title Q148N, a Novel Integrase Inhibitor Resistance Mutation Associated with Low-Level Reduction in Elvitegravir Susceptibility.
Citation ARHR
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 7
Lab Parent Strain NL43, CONB


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
CA352404-G140S_Q148N G140S Q148N PhenoSense DTG 0.5 
      PhenoSense EVG 4.2 
      PhenoSense RAL 0.6 
CA352404-None   PhenoSense DTG 1.1 
    PhenoSense EVG 1.3 
    PhenoSense RAL 1.0 
CA352404-Q148N  Q148N PhenoSense DTG 0.7 
     PhenoSense EVG 4.5 
     PhenoSense RAL 1.0 
G140S_Q148H G140S, Q148H V151I PhenoSense DTG 3.4 
      PhenoSense EVG >150 
      PhenoSense RAL >150 
G140S_Q148N G140S Q148N, V151I PhenoSense DTG 0.6 
      PhenoSense EVG 3.1 
      PhenoSense RAL 0.6 
Q148H Q148H V151I PhenoSense DTG 0.6 
      PhenoSense EVG 5.5 
      PhenoSense RAL 19 
Q148N  Q148N, V151I PhenoSense DTG 0.6 
     PhenoSense EVG 2.4 
     PhenoSense RAL 0.7