Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Zhang (2018)
Title Accumulation of multiple mutations in vivo confers cross-resistance to new and existing integrase inhibitors.
Citation J Infect Dis
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 12
NumPts 11
Subtype B, C


Clinical IN Isolates

25296D 25296D.PH-INT-05 INI  G140S, Q148H T97A M50I, L101I, S119R, S123C, S283G  
31945A 31945A.PH-INT-04 INI  G140S, Q148H  S17N, V31I, L101I, T125A, K156N, V165I, K215N, S255R  
33973A 33973A.PH-INT-01 INI  G140S, Q148H  S24SN, M50I, L101I, S119R, S123C, F223FL, S283G  
39642A 39642A.PH-INT-02 INI  G140S, Q148H  L101I, S119P, T122I, K136N, I203M, Q216H  
41133A 41133A.PH-INT-25 INI  G140S, Q148H  S17N, L101I, V201X, I208L  
52246C 52246C.PH-INT-18 INI  G140S, Q148H L74M, T97A M50I, L101I, I113L, S119R, T124A, F139Y, S283G  
53528A 53528A.PH-INT-01 INI  G140S, Q148H L74M, T97A M50I, L101I, I113L, S119R, T124A, F139Y, S283G V201VG 
54080A 54080A.PH-INT-27 INI  G140S, Q148H  K7KR, R20RK, S39SC, M50X, L101I, K111KQ, G193E, V201I, D286N S255SC, P261PS 
  54080A.PH-INT-01 INI  G140S, Q148H  K7R, R20K, M50T, L101I, K111Q, G193E, V201I, D286N  
54271B 54271B.PH-INT-08 INI  G140S, Q148H  S24N, S39C, I113V, T124N, T125A, V201I A175S 
63867A 63867A.PH-INT-01 INI  G140S, Q148H T97A K14R, S24N, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211Q, L234I, D278A  
66786A 66786A.PH-INT-04 INI  G140S, Q148H L74M, T97A M50I, L101I, K103R, I113L, S119R, T124A, F139Y, S283G