Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Wares (2014)
Title The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness.
Citation Retrovirology
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 3
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
M50I  V151I TZM-McGill DTG 1.9 
     TZM-McGill EVG 5.5 
     TZM-McGill RAL 0.5 
M50I_R263K R263K V151I TZM-McGill DTG 16 
      TZM-McGill EVG 34 
      TZM-McGill RAL 3.6 
R263K R263K V151I TZM-McGill DTG 8.6 
      TZM-McGill EVG 21 
      TZM-McGill RAL 1.9