<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Nguyen (2018)
Title Prevalence and clinical impact of minority resistant variants in patients failing an integrase inhibitor-based regimen by ultra-deep sequencing.
Citation J Antimicrob Chemother
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 122
NumPts 122
Subtype B, CRF02_AG, A, D, F, G, C

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 122 Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
060001EIA 060001EIA INI  Y143R L74M, E138ED K71KQ, I72X, E96N, L101I, S119G, T122I, T124N, T125A, V201I  
060002CAS 060002CAS INI    L101I, T112V, T124N, T125X, G134D, I135V, I161L, V201I, T206S, L234I, S255N  
060003MAC 060003MAC INI    I72V, L74I, L101I, T112V, I113V, T124A, T125A, G134D, I135V, K136T, E157Q, K160Q, V201I, L234I, R269K  
060004BAM 060004BAM INI  N155H E138D, V151I L101I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, D232N, L234I, R269K  
060005SID 060005SID INI  Y143YC  L74I, S119P, T125A, K136Q, M154I, H171Q, D256E E152EQ 
060006FEH 060006FEH INI    L101I, T112X, T124G, T125A, K127KR, G134N, I135V, K136T, G163M, V201I, T206S, L234I  
060007JUT 060007JUT INI    I73V, L101I, T206S H51D 
060008GEP 060008GEP INI  N155H T97A L101I, S119R, T125V, G163E, A205S  
060009SUC 060009SUC INI  N155H  I84V, T112I, T122I, T124N, M154I, V201I, Q216R, K219Q, D256E, Q274K  
060010MAN 060010MAN INI    I72IV, A91AT, T112V, I113V, S119ST, T124A, T125A, V126M, I135V, V201I, K211KR, L234I, K244R  
060011SEI 060011SEI INI    I72V, L101I, T112V, S119P, T122I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I  
060012SIT 060012SIT INI    L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218X, K219KQ, L234I, A265V  
060013MAM 060013MAM INI    I72V, T112I, I113V, T124X, K156N, V201I, E212A, T218S, I220L  
060014CHH 060014CHH INI  N155H V151I I72V, L101I, K111T, S119T, I220V, D232N  
060015BUA 060015BUA INI  N155H  I84IM, L101I, S119P, T122I, K173R, G193E, V201I H51D 
060016GRL 060016GRL INI  N155H  L101I, I113V, S119R, T125A, I220L  
060018LEP 060018LEP INI    I72V, M154I, V201I H51D 
060020MAD 060020MAD INI  N155H  L101I, K173R, F181L, K211R, Y227F, S230N  
060021ZIE 060021ZIE INI  Q148R  I72V, K111Q, T112V, I113V, T124A, V201I, D232N, L234I  
060022MIR 060022MIR INI    L74I, V75I, L101I, K111T, T124A, T125A, D167E, A179S, V201I, I220L, Y227F G106GR 
060023PAY 060023PAY INI   T97TA I72V, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I A76AV 
060024JEM 060024JEM INI  Y143R  K136Q, V201I, D256E  
060025CRP 060025CRP INI  N155H  I72V, L101I, S119P, T122I, E170A, T218I, A265V  
060027FES 060027FES INI  N155H V151VI I72V, K111R, K136R, M154I, K173R  
060028WEJ 060028WEJ INI  N155H V151I L101I, K111T, T122I, D167E  
060030OBC 060030OBC INI    I60M, K71Q, A91T, A98G, L101I, G106A, T112V, S119R, T124A, K136Q, V201I, A205S, T206S, L234V, D256E  
060031ROC 060031ROC INI  G140S, Q148H  V201I, T206S  
060032LAP 060032LAP INI    M154I, K173R  
060033RAC 060033RAC INI    I72V, L101I, S230N  
060036PAH 060036PAH INI   T97A I60IV, I72IV, L101I, G106A, K111Q, T112V, T124A, T125X, V126A, G134N, K136T, V165I, V201I, T206S, I220IT, L234X  
060037GUT 060037GUT INI    I72V, S119P, T122I, T124A, V165VI, V201I, K211KR, K219X, I220L  
060038BAP 060038BAP INI  E92Q  L74I, Y99YH, S119P, I220L  
060040DEP 060040DEP INI    L101I, T112V, T124A, T125A, G134N, K136T, D167E, V201I, T206S, Y227F, L234V, D256E  
060042CHE 060042CHE INI    L101I, T112A, T124A, T125A, V201I, D232E, L234I, V249I R187S 
060043POS 060043POS INI  E92Q, S147G, N155H L74M, T97A I60M, I73V, T112V, I113V, T124A, T125A, K136Q, I162V, L234V  
060044LAM 060044LAM INI  G140S, Q148H T97A M50K, T124A, T125A, F139Y, V201I, I208L  
060046CHL 060046CHL INI    S57G, I72V, L101I, G106GA, T112V, T124A, T125A, G134S, I135V, K136T, V201I, T206S, L234I, D256E  
060047WAT 060047WAT INI    L101I, T112V, T124TN, T125V, G134D, K136T, V201I, T206S, L234I, D256E, R269K, C280CR H51D 
060048ITM 060048ITM INI  E138K, S147SG, Q148R H114HY I72V, I84M, K111R, T112V, I113V, T124N, T125A, V201I, T206S, K211Q, L234I  
060049FUP 060049FUP INI  T66I Q146QK, G163R S57G, I72V, Q95N, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K G247GE, V281M 
060050KIC 060050KIC INI    L63I, L74I, L101I, T112V, I113V, S119P, T124A, T125A, G134N, D167E, V201I, T206S, I208L, T218I  
060051PRA 060051PRA INI    M50I, I72V, S119P, T122I H51D 
060052MOY 060052MOY INI    I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, Q221QH, L234I, S255G V281M 
060053MIT 060053MIT INI    L101I, K111N, V201I, T218S, S230N  
060054MAV 060054MAV INI    L101I, T124A, I135V, K160T  
060056RIJ 060056RIJ INI  E92Q, N155H S153SY L101I, T112V, I113V, T124A, T125A, G134N, I135V, K136T, V151VG, V201I, A205AT, T206S, K215N, Q216K, D232E, L234I, D256E V150VG 
060059KAB 060059KAB INI    I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, R269K H51D, Y271Y* 
060060BOD 060060BOD INI  T66TI  V75VI, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, K160Q, F181L, G193D, S195T, V201I, I203M, T206S, L234I, I268L, D270H  
060062TEL 060062TEL INI  N155H  I72V, P90S, S119P, T122I, T124A, T125A G70R 
060063SAG 060063SAG INI  E138K, G140S, Q148H T97A T66X, I72V, L101I, I113L, S119SR, T124A, T125TA, D256E  
060064BEL 060064BEL INI    S119P, T124A, Q177L, G193D, I203M, I208M, D256E, Q274QR  
060067CHD 060067CHD INI  E138K, G140S, Q148H L68V, T97A I60L, L101I, T112V, I113L, T124TA, D232E  
060070DOC 060070DOC INI    A91AT, L101I, S119P, T124TA, I135IV, V165I, V201I, R269K  
060071GES 060071GES INI    L101I, T125A, K156N, E198D, V201I, T206S, D229E, L234T, D278N  
060072GNM 060072GNM INI  E92Q  L101I, K111R, T112K, T124A, T125A, G134N, I135V, K136T, G193X, V201I, T206S, I208IL, K211T, L234I  
060074NGM 060074NGM INI    I113V, T124A, T125A, G134GE, L234I, A265V  
060075MPN 060075MPN INI    I72V, Q95P, A98S, L101I, A105AV, T112I, S119P, T122I, T124A, T125A, V201I, T206S, L234I, D256E  
060076VAF 060076VAF INI    A98G, L101I, K111T, S119P, T124N, T125A, V201I, T206S, D207E, M275V  
060078FEP 060078FEP INI  Q148R  L101I, T124A, T125A, K211Q, S230N, L234V  
060079KIP 060079KIP INI    L63V, I72V, L74I, E96D, T112V, T124A, G134N, V201I, L234I, S255G, A265V  
060080MOP 060080MOP INI   T97A L101I, I113V, S119G, T124N, T125A, V165I, V201I  
060081POJ 060081POJ INI  N155H  I72V, L101I, S119P, T122I, T125A, V201I  
060082LIP 060082LIP INI  E138EK, Q148R  L101I, G106A, K111T, T122I, V201I  
060085ELM 060085ELM INI    L101I, V165I, Y227F, D256E, A265V  
060086DER 060086DER INI    I72V, T112I, I113L, T124N, T206S, I251V, D256E  
060087LEP 060087LEP INI  G140S, Q148H T97A, E138D L101I, T122I, T125A, R187K, K188R, K240R, D256E  
060088AMC 060088AMC INI    S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, I220IV, L234I, R269K  
060089MOJ 060089MOJ INI  N155H  L101I, T124A, A265V  
060090SOS 060090SOS INI    L101I, T124A, G134D, K136T, K188KR, V201I, T206S, E212A, T218I, L234I, S255N, D256E, I268L V281VM 
060091LAJ 060091LAJ INI    L101I, S119P, T122I, T124A, F139L, V201I, K215N, I220L  
060092AVS 060092AVS INI    I72V, L101I, S119P, T122I, V165I  
060096OMA 060096OMA INI  N155H  I84M, L101I, K111Q, T124A, T125A, I135V, K136Q, K156KN, K211R, L234I, I251L, A265V, D278A  
060097REV 060097REV INI  N155H E92EG L101I, K111T, T112TA, S119G, T122I, T124N, E212A, K219N, N222K  
060099CAP 060099CAP INI    I72V, A91T, S119P, T122I, T125A, F139L, V201I, Q216N, S230N  
060100MVC 060100MVC INI    I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167DE, G189R, V201I, T206S, K211KR, Q216QH, N222NK, L234I, A265AV  
060101BEG 060101BEG INI  G140S, Q148H V151A S119P, T122I, T124A, K219N, N222K  
060103MAV 060103MAV INI    I72V, T112I, I113V, T124A, T125A, V126F, G134N, I135V, K136Q, D167E, V201I, K211R, Q216H, L234I  
060104COG 060104COG INI    T124A, T125A, G163Q, K211Q, T218S, S230N D202DV 
060108DID 060108DID INI    Q95S, L101I, T112V, S119P, T124A, T125A, G134S, K136T, V201I, T206S, T218I, L234I  
060110DUM 060110DUM INI    V88VI, L101I, K111KT, I162IV, K219N, I220L, N222K, D232E, N254K  
060111RAV 060111RAV INI    K156N, R187K, K188R, T218S  
060112KAK 060112KAK INI  N155H Q95QK, T97TA M50MI, H51X, L101I, T112V, I113L, S119SR, T124N, T125A, G134N, K136T, V165I, V201I, T206S, L234I, S255N  
060113ALM 060113ALM INI    I72V, E96D, L101I, G106A, T112V, I113V, T124A, D167E, G193E, I208M, I220L, L234I  
060115ASF 060115ASF INI    L101I, T112V, T124A, T125A, G134D, I135V, K136T, G163V, V201I, T206S, R224W, L234I  
060116VAA 060116VAA INI  N155H  I72V, I113V, T124A, T125A, V176I, G193E, V201I, T206S, L234H  
060117COL 060117COL INI  N155H S230R G193E, V201I  
060118DUF 060118DUF INI    I72V, K111T, T124A, I135V, I220L  
060119AMA 060119AMA INI    I72V, L74I, T112I, T124A, T125A, V126M, G134D, K136Q, D167E, V201I, T218S, L234I, D256E  
060120VER 060120VER INI    I72V, L74I, T112I, T124A, T125A, V126M, G134D, K136Q, D167E, V201I, T218S, L234I, D256E  
060121DEM 060121DEM INI    I72V, L101X, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E  
060122KAF 060122KAF INI    L101I, T124S, T125A, K136Q, D167E, K173KR, V176L, V201I, T218I, L234V K159KT 
060123LAS 060123LAS INI    I72V, T124A, K156N, K219N, N222K  
060124TIN 060124TIN INI  E92EQ  S57SG, L63I, L74I, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G163X, V201I, T206S, L234I, S255SG, M275V  
060125TUG 060125TUG INI    I72V, L101I, T112V, S119P, T124A, K136Q, D167E, V201I, T206S, L234I, D256E, D270H  
060126OLA 060126OLA INI    K71R, I72V, T112I, T124N, T125V, G163E  
060127KEC 060127KEC INI   F121FC I72V, L74I, L101I, T112V, S119P, T125A, G134N, I135V, K136T, Y143X, H171HR, V201I, T206S, Q221T, L234V, N254S, D256E  
060130KOJ 060130KOJ INI    L101I, T112V, T124S, T125A, G134N, K136T, G163S, K173R, V201I, T206S, K211Q, T218TI, Q221S, N222NK, L234I, R269K  
060131GOL 060131GOL INI   V151I I72V, S230N, D232E  
060132TOM 060132TOM INI    L74I, A91T, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, R269K  
060133RAM 060133RAM INI    I73V, L101I, T112I, T124A, T125A, G134D, K136T, G163T, V201I, T206S, L234I