Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Tsiang (2016)
Title Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
Citation Antimicrob Agents Chemother
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 13
NumPts 13
Subtype B, D, CRF01_AE, C, F, A, CRF02_AG


Clinical PR Isolates

1475MV 01CM.1475 None    I13V, K14R, K20I, E34A, M36I, R41K, H69K, L89M  
92UG037 92UG037A35 None    I13V, E35D, M36I, R41K, R57K, H69K, L89M  
93BR020 93BR020 None    K14R, I15V, E35D, M36V, R41K, R57K, Q61S, K70R, L89M, N98H  
93IN905 ISO301905 None    T12S, K14R, I15V, L19I, M36V, R41K, L63P, H69K, L89M, I93L  
98UG57128 98UG57128 None    I13V, R41K, K43R, L63P  
98US_MSC5016 98US_5016 None    T12A, I15V, G16E, L19I, M36I, N37S, L63T, I64M, H69K, I72V, L89M, I93L  
99UGA07412 99UGA07412 None    M36I, R41K, D60E, I64V, H69Q  
BB_85US_Ba-L 85US_Ba-L None    M36I, V77I  
BB_96TH_M02138 96TH_02138 None    I13V, K20R, E35D, M36I, R41K, H69K, L89M  
BB_96TH_NP1046 96TH_1046 None    I13V, E35D, M36I, R41K, H69K, K70R, L89M  
BZ167 BZ167 None    I13V, L63P  
US1 US1 None    T12S, L63P  
US4 US4 None    I13V, N37S, R41K, R57K, D60E, I64V