<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Saravanan (2013)
Title Darunavir is a good third-line antiretroviral agent for HIV type 1-infected patients failing second-line protease inhibitor-based regimens in South India.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 87
NumPts 87
Subtype C, A


Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
YRG01 YRG01 PI  M46I, I54IV, I84V, L90M L10F T12S, L19I, K20KR, M36I, R41K, L63P, H69K, A71V, L89M, I93L  
YRG02 YRG02 PI  M46L, V82A, L90M L10F, Q58E, T74P I15V, L19I, K20R, M36I, R41K, K55KR, I62V, L63P, I64V, H69K, L89M, I93L  
YRG03 YRG03 PI  M46I, I54V, V82A L10F, L24I, L33F T12S, K14KR, I15V, L19I, E34Q, E35D, M36X, R41K, L63P, H69K, I93L  
YRG04 YRG04 PI  M46L, I54V L10F, L33F T12S, I15V, L19I, K20T, E35D, M36L, R41K, L63P, H69K, A71V  
YRG05 YRG05 PI  D30N, M46MI, I54V, V82A L10F, L33F, N88D I15V, L19T, K20T, E35X, M36I, N37NT, R41K, L63P, I64IL, H69X, A71V, I93L  
YRG06 YRG06 PI  M46I, L76V, L90M L10F T12S, I15V, L19M, K20I, E21D, E35G, M36I, R41K, K55R, D60E, Q61E, I62V, L63P, H69K, A71V, I72M, I85V, I93L  
YRG07 YRG07 PI  D30N N88D, L89V L10M, T12S, I13V, I15V, L19T, K20T, E35N, M36I, P39A, R41K, K45R, K55N, Q61D, L63P, H69K, T74S, V82I, I93L E21N 
YRG08 YRG08 PI  M46I, L76V, V82F L23LI L10I, T12S, L19T, M36I, L63P, H69K, I72V, L89M, I93L  
YRG09 YRG09 PI  G48V, I54V, V82A L33F, N83D L10I, T12S, I13V, I15IV, L19I, M36I, N37D, Q61N, L63P, H69K, T74S, L89I, Q92R, I93L  
YRG10 YRG10 PI  M46I, I54V, V82A, L90M T74P L10I, T12S, L19T, K20I, M36I, R41K, I62V, L63P, H69K, A71V, L89M, I93L  
YRG11 YRG11 PI  M46I, L76V, I84V L10F T12S, I15V, L19I, K20KR, E34EQ, M36I, R41K, Q61QH, L63P, H69K, L89M  
YRG12 YRG12 PI  M46I  L10I, T12A, I13V, E35D, M36I, N37D, R41K, R57K, H69K, K70R, L89M  
YRG13 YRG13 PI  I84V, L90M N83ND T12S, I13IV, I15V, L19I, K20R, E35ED, M36I, R41K, L63P, H69K, A71I, V82I, L89T, I93L G94D 
YRG14 YRG14 PI  D30N L33LF T12S, I15V, G16A, L19X, K20KT, E35ED, M36X, N37ND, R41K, K45X, L63T, I64IV, H69K, I93L  
YRG15 YRG15 PI  M46I, I54V, V82A, L90M L10F, K43T, T74TP Q7D, T12X, I15V, L19T, K20I, E35ED, M36I, R41K, I62IV, L63P, H69K, L89M, I93L  
YRG16 YRG16 PI  M46I, L76V, L90M L10LF, L23LI T12S, I13V, L19X, K20I, E34ED, E35N, M36I, N37D, R41K, D60E, Q61X, L63P, H69K, V82VI, L89M, I93L  
YRG17 YRG17 PI  V32I, M46I, I54V, L76V, I84V L10F, V11VI, Q58E T12S, I15V, L19I, K20R, M36I, R41K, K55KR, L63P, C67CY, H69K, A71V, I93L  
YRG18 YRG18 PI  M46I, I54L, L76V, I84V L10F, L24I, L33F, N83D I13V, I15V, G16E, L19I, E35D, M36L, N37S, K45R, R57K, Q61N, L63T, H69K, T74S, L89M  
YRG19 YRG19 PI  I54V, L90M V11I L10I, T12S, I15V, L19I, K20KR, M36I, R41K, I62V, L63S, I64L, H69K, A71V, L89LI, I93L  
YRG20 YRG20 PI  M46I, V82T L10F, L24I, T74P K14KR, I15IV, G17D, L19I, K20R, M36I, R41K, L63P, H69K, L89M, I93L  
YRG21 YRG21 PI  M46L, I54V, V82A, L90M Q58E, T74P I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93L L10W 
YRG22 YRG22 PI  M46I, I54V, V82A, L90M T74P L10I, T12S, L19T, K20I, M36I, R41K, I62V, L63P, H69K, A71V, L89M, I93L  
YRG23 YRG23 PI  M46I, I54V, L76V, V82A L10F, L24I T12P, L19T, K20M, M36I, R41K, L63P, H69K, A71V, L89M, I93L G16N 
YRG24 YRG24 PI  M46I, I54V, V82A L10F, L24I T12S, I15V, L19T, M36I, R41K, I62V, L63P, H69K, A71T, I93L  
YRG25 YRG25 PI  M46I, I84V, L90M G73S L10I, T12S, I15V, L19I, K20X, L24F, E35ED, M36I, N37D, K55KR, Q61QH, I62IV, L63P, H69K, K70KR, A71I, I93L  
YRG26 YRG26 PI  M46I, I50L, L90M G73S T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45R, L63P, H69K, A71AT, I72V, I93L  
YRG27 YRG27 PI  D30N L33LF T12S, I15V, G16A, L19X, K20KT, E35ED, M36X, N37ND, R41K, K45X, L63T, I64IV, H69K, T74TA, I93L  
YRG28 YRG28 PI  M46I, L76V, I84V L10F T12S, I15V, L19I, K20KR, E34EQ, M36I, R41K, Q61QH, L63P, H69K, L89M, I93IL  
YRG29 YRG29 PI  M46I, I54V, V82A, L90M L10F, K43T, T74P Q7D, T12X, I15V, L19T, K20X, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93L  
YRG30 YRG30 PI  I54V, V82A, L90M G73T L10I, I15V, L19I, K20I, M36I, N37D, L63P, H69K, A71V  
YRG31 YRG31 PI  M46I, I50V, I54V, L76V, V82A L23I, L33F T4S, L10V, T12S, I13V, L19I, K20R, M36I, R41K, K43E, K55R, L63P, H69K, T74A, L89M, I93L  
YRG32 YRG32 PI  G48V, I54V, V82T K43T L10I, K14KR, I15V, E35D, M36I, N37T, R41K, I62V, L63P, I64M, H69K, L89M, I93L, T96P  
YRG33 YRG33 PI  L90M  T12S, I15V, L19I, M36V, R41K, L63P, H69K, I93L  
YRG34 YRG34 PI  M46I, I54IV, L90M G73S T4TS, I15V, L19I, K20T, E35ED, M36I, R41K, L63A, H69K, A71V, I93L R8R* 
YRG35 YRG35 PI  M46I, I54V, V82A, L90M L10F W6WG, I15V, L19I, M36I, N37D, L63P, H69K, L89M, I93L W42WG 
YRG36 YRG36 PI  G48V  L10I, T12S, I15V, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93L  
YRG37 YRG37 PI  V82A  T12S, K14X, I15V, L19I, M36I, R41K, L63P, I64V, H69K, I93L  
YRG38 YRG38 PI  M46I, I54A, V82A K43T L10V, T12S, I15V, L19I, K20R, M36I, R41K, K55R, I62V, L63P, H69Q, L89M, I93L  
YRG39 YRG39 PI  L90M  T12S, I13V, I15V, L19I, K20I, M36I, R41K, L63P, H69K, T74S, L89I, I93L  
YRG40 YRG40 PI  L90M G73T L10V, I15V, G17D, L19I, K20I, M36I, L63P, H69K, A71V, I93L  
YRG41 YRG41 PI  V82A  I15V, L19I, M36I, R41K, L63T, H69K, T74S, I93L  
YRG42 YRG42 PI  M46I, L90M G73S T12S, I15V, L19I, K20I, E35D, M36I, N37D, K45KR, L63P, H69K, A71I, V75I, I93L  
YRG43 YRG43 PI  M46I, L76V, I84V L10F T12S, I15V, L19I, M36I, L38W, R41K, L63P, H69K, A71V, I93L  
YRG44 YRG44 PI   L23LI L10LI, T12A, I13V, E35D, M36I, N37D, R41K, R57K, H69K, L89M  
YRG45 YRG45 PI  M46I, I54V, V82A L10LF T12P, K14R, I15V, G16E, M36I, R41K, L63S, H69K, L89M, I93L  
YRG46 YRG46 PI  M46I, L90M G73S T12S, I15V, L19I, K20T, E35D, M36I, R41K, K55N, Q61H, L63P, H69K, A71V, T74S, I93L  
YRG47 YRG47 PI  I54IV  T12S, L19I, M36I, R41K, L63T, H69K G17N 
YRG48 YRG48 PI  M46I, I54V, V82A L24I, K43T L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K55R, R57RK, I62V, L63P, H69K, T74X, V75VI, L89M, I93L  
YRG49 YRG49 PI  V82A, L90LM L24LI L10I, T12S, K14R, I15V, L19T, K20R, M36I, R41K, I62IV, L63P, H69K, T74S, L89M  
YRG50 YRG50 PI  I54V M46V I3V, I15V, E35D, M36V, N37D, D60E, L63P, H69K, A71V  
YRG51 YRG51 PI  I54V, V82A L76S L10I, T12S, I15V, L19I, K20R, M36I, R41K, K45R, I62V, L63A, H69K, A71V  
YRG52 YRG52 PI  M46I, I54V, V82A L24I, K43T L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, I62V, L63P, H69K, T74A, L89M, I93L  
YRG53 YRG53 PI  M46I, V82A L10F, L24I, Q58E T12S, I15V, L19T, K20I, M36I, L63P, H69K, K70R, L89M  
YRG54 YRG54 PI    I13IV, K14KR, I15V, L19I, M36I, R41K, K43KR, L63P, H69K, L89LM, I93L  
YRG55 YRG55 PI  L90M G73S I15V, L19I, K20T, E35D, M36I, N37D, K45R, L63P, H69K, A71V, I85IV, I93L  
YRG56 YRG56 PI    T12S, I15V, L19I, E35D, M36I, L63P, H69K, V82VI, L89M, I93L  
YRG57 YRG57 PI  I54V, V82A K43KT, G73S L10I, I15V, L19I, M36L, N37S, I62V, L63P, H69K, A71V, I72IM, I85IV, I93L  
YRG58 YRG58 PI    T12S, K14R, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
YRG59 YRG59 PI  M46I, I54V, V82F, L90M  L10X, T12S, L19T, K20I, E35N, M36I, R41K, K45Q, D60E, Q61E, I62V, L63P, I64V, H69K, L89M, I93L  
YRG60 YRG60 PI    T12S, I15V, L19I, M36I, R41K, D60DE, L63S, I64L, H69K, L89M, I93L  
YRG61 YRG61 PI  M46I, I54V, N88S  T12S, I15V, L19I, K20I, E35G, M36I, R41K, I62V, L63P, H69K, T74A, L89M, I93L  
YRG62 YRG62 PI   G73GS T12S, I15V, L19I, M36I, R41K, L63P, H69K, I85IV, I93L  
YRG63 YRG63 PI  M46I, V82VA L10F I3V, I15L, M36I, N37S, R41T, L63P, H69K, I93L  
YRG64 YRG64 PI  V82A  T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
YRG65 YRG65 PI  M46I, V82A L10F T12S, L19I, M36T, R41K, L63P, H69K, L89M, I93L  
YRG66 YRG66 PI  L90LM  T12S, I15V, G16A, L19I, E35ED, M36V, R41K, K45KR, L63P, H69K, I93L  
YRG67 YRG67 PI    T12S, K14R, L19I, M36I, R41K, Q61E, L63P, H69K, V82I, I93L  
YRG68 YRG68 PI    L10V, T12P, I15V, G16GE, L19I, M36I, N37NS, R41K, L63P, H69Q, I93L  
YRG69 YRG69 PI  I54V, V82A Q58E L10I, I15V, G17D, L19I, K20R, E35D, M36I, R41K, D60E, Q61QE, I62IV, L63T, H69K, L89M, I93L  
YRG70 YRG70 PI  M46I, I54V, L90M G73S I15V, L19I, K20T, E35D, M36I, R41K, I62V, L63A, H69K, A71I, I93L  
YRG71 YRG71 PI  M46I, I54V, V82A L24I, K43T L10V, T12S, I15V, L19I, M36A, R41K, K55KR, I62V, L63P, I64IV, H69K, L89M, I93L  
YRG72 YRG72 PI    L10X, T12S, L19T, M36I, L63T, H69K, L89M, I93L  
YRG73 YRG73 PI  M46I, I54V, V82A, L90M Q58QE, G73T L10I, K14KR, L19X, K20R, E35D, M36I, N37D, K45R, I62V, L63P, I66IM, H69K, A71AV, V75VI, P79D, N83NS, I93L, C95F  
YRG74 YRG74 PI    T12P, K14R, I15V, M36I, R41K, L63P, H69K, L89M, I93L  
YRG75 YRG75 PI    T12S, I13V, I15V, L19I, M36I, R41K, D60E, L63P, H69K, K70R, L89I, I93L  
YRG76 YRG76 PI  I54A, V82L, L90M Q58E L10I, I13IV, I15V, G16X, L19I, K20T, E35D, M36I, N37D, R57K, Q61N, L63T, H69K, A71V, L89M, I93L  
YRG77 YRG77 PI  M46I, I54IV L23I, L33LF, K43KT, F53L I13V, K14R, I15V, L19I, E35D, M36L, N37S, R41K, L63P, H69K, A71X, L89T, I93L  
YRG78 YRG78 PI    T12S, L19T, E34D, M36I, Q61E, L63P, H69K, L89M, I93L  
YRG79 YRG79 PI  M46I, I54V, V82F, L90M K43T L10I, L19I, E35D, M36V, I62V, L63P, H69K, I72IV, T74A, L89M, I93L  
YRG80 YRG80 PI  M46I, I54V, V82A L10F, L24I, Q58E I15V, L19I, K20R, E35D, M36I, N37S, R41K, D60E, Q61E, I62IV, L63P, H69K, L89M, I93L  
YRG81 YRG81 PI    K14KR, I15V, L19I, M36I, N37ND, R41K, L63X, E65ED, H69K, I72IV, L89M, I93L  
YRG82 YRG82 PI  M46I, I54V, V82A L10LF T12P, K14R, I15V, G16E, M36I, R41K, L63S, H69K, L89M, I93L  
YRG83 YRG83 PI  M46I, L90M G73S T12S, I15V, L19I, K20T, E35D, M36I, R41K, K55N, Q61H, L63P, H69K, A71V, T74S, I93L  
YRG84 YRG84 PI  M46I, L90LM F53FL, G73S T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63P, H69K, A71V, T74S, I93L  
YRG85 YRG85 PI    T12S, L19I, E34ED, E35ED, M36I, R41K, K45R, Q61E, L63P, H69K, A71AV, I72V, L89T, I93L  
YRG86 YRG86 PI  M46I  L10Y, T12S, I13V, I15V, L19I, E34EQ, E35D, M36I, N37D, R41K, K45KR, L63P, H69K, T74A, L89T, I93L  
YRG87 YRG87 PI   L10F T12P, I15V, L19I, M36V, R41K, L63P, H69K, T91S