<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sachithanandham (2016)
Title Effect of HIV-1 Subtype C integrase mutations implied using molecular modeling and docking data.
Citation Bioinformation
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 102
NumPts 102
Subtype C


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Page 1   from Isolate 1 to Isolate 100 from Total 102 Clinical IN Isolates

SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
06/334 06/334 None    V31I, K42Q, L101I, T112V, I113V, T124A, T125A, D167E, H171Q, V201I, L234I, R269K, D278A  
06/401 06/401 None    S17N, S39N, D41N, K42Q, L45V, L74I, L101I, T112V, T124A, K136Q, V201I, I220V, L234I, K240R, R269K, D278A  
07/339 07/339 None    E11D, V31I, V32I, V37I, S39N, K42Q, I84L, L101I, T112V, T124A, K136Q, K188R, V201I, I203M, L234I, D278A  
07/507 07/507 None    K14R, V31I, K42Q, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I220L, L234I, R269K, D278A  
07/529 07/529 None    K14R, V31I, K42Q, L45Q, I72V, L74I, I84M, L101I, T112V, T124A, T125S, G134N, K136Q, V201I, I203M, T218L, L234I, R269K, D278A  
07/552 07/552 None   L74M K14R, V31I, K42Q, F100Y, L101I, T112V, T124A, T125A, K127R, K136Q, K188R, V201I, L234I, R269K, D278A  
07/556 07/556 None    E10A, S17N, L28I, D41N, K42Q, I60V, F100Y, L101I, T112V, I113L, T124A, T125A, G134D, K188R, S195C, V201I, I203M, T218I, L234I, D278A  
07/561 07/561 None    K14R, V31I, D41N, K42Q, L45Q, I72V, F100Y, L101I, T112V, I113V, T124A, T125A, K136Q, K188R, A196P, V201I, L234I, D278A  
07/567 07/567 None    R20K, M22L, V37I, S39R, D41N, K42Q, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, Q221S, L234I, D278A  
07/588 07/588 None    V31I, D41N, K42Q, L45Q, I84M, P90S, F100Y, L101I, T112V, T124A, T125A, K136Q, K188R, V201I, I203M, K211R, L234I, R269K, D278A  
07/591 07/591 None    V31I, D41N, K42Q, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, D278A  
07/609 07/609 None    K14R, V32I, S39C, L101V, T112V, T125A, K136Q, H171Q, V201I, I203M, I208L, L234I, D278A  
07/614 07/614 None    V31I, D41N, K42Q, L74I, I84L, F100Y, L101I, T112V, S119P, T124A, T125A, G134D, K136R, V201I, I203M, L234I, D278A  
07/638 07/638 None    V31I, K42Q, L101I, T112V, T124Q, T125A, K136Q, K173R, V201I, K211R, L234I, R269K, D278A  
07/639 07/639 None    K14R, V31I, K42Q, L74I, I84M, F100Y, L101I, T112V, I113V, T124A, T125A, V201I, T206S, E212A, L234I, D278A  
07/643 07/643 None    K14R, V31I, K42Q, L45Q, L101I, T112V, T124A, T125A, K136Q, G163A, V201I, T218I, L234I, D256E, R269K, D278A  
07/658 07/658 None    K14R, L28I, P30A, D41N, K42Q, L101I, T112V, T124A, T125A, K136Q, I141V, V201I, L234I, D278A  
07/663 07/663 None    R20K, L45Q, M50I, P90S, L101I, T112V, I113V, T125A, K136R, G163E, V201I, I220V, L234I, D278A  
07/792 07/792 None    K14R, L28I, K42Q, L74I, I84M, L101I, T112V, T124A, T125A, K136Q, A196P, V201I, T218S, L234I, D278A  
07/800 07/800 None    V31I, D41N, K42Q, L45Q, L74I, F100Y, L101I, T112V, T124A, T125A, K136Q, E157Q, K160R, V201I, Q221S, L234I, D278A  
07/821 07/821 None    V31I, D41N, K42Q, L45V, I84M, L101I, K111R, T112V, T125A, K136Q, K173R, V201I, T218S, L234I, R269K, D278A  
08/03 08/03 None    V31I, D41N, K42Q, L45Q, L74I, I84M, E96D, L101I, T112V, T124A, T125A, K136Q, H171Q, V201I, I203M, A205S, K211R, Q221S, L234I, D278A  
08/08 08/08 None   Q95K L45Q, I84L, F100Y, L101I, T112V, T124A, T125A, V165I, I200L, V201I, I203M, L234V, D278A  
08/24 08/24 None   L74M V31I, L45Q, F100Y, L101I, T112V, T124A, T125A, K136Q, F181L, K188R, E198D, V201I, T218L, Q221S, L234I, D278A  
08/320 08/320 None    K14R, V31I, D41N, K42Q, L45Q, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, K188R, V201I, L234I, R269K, D278A  
08/321 08/321 None    V31I, D41N, K42Q, L45Q, F100Y, L101I, T112V, I113L, T124N, T125A, V165I, H171Q, V201I, L234I, R269K, D278A  
08/33 08/33 None    K14R, V31I, K42Q, I60V, L101I, T112V, S119P, T122I, T125A, H171Q, V201I, I220L, L234I, R269K, D278A  
08/334 08/334 None    K14R, S17N, A21S, L28I, K42Q, L63I, I72V, L74I, I84L, F100Y, L101I, T112V, S119T, T124A, T125A, K136R, E198D, V201I, L234I, D278A  
08/336 08/336 None    K14R, V31I, V32I, D41N, K42Q, L45Q, I60V, I84L, L101I, T112I, I113V, T124A, T125A, K136Q, K160R, V201I, A205S, L234I, R269K, D278A  
08/352 08/352 None    R20K, L101I, T112V, T122I, T124N, K136Q, G163E, V201I, I220V, L234I, R269K, D278A  
08/521 08/521 None    V31I, D41N, K42Q, L45Q, L74I, L101I, T112V, S119T, T124S, T125A, I135V, K136Q, D167E, V201I, L234I, S255N, D278A  
08/590 08/590 None    V31I, D41N, K42Q, L45Q, F100Y, L101I, T112V, S119T, T124N, T125A, K136Q, V201I, L234I, R269K, D278A  
08/599 08/599 None    V31I, K42Q, I72V, L74I, L101I, K111R, T112V, T124A, T125A, K136Q, I220L, L234I, D278A  
08/603 08/603 None    V31I, D41N, K42Q, L45Q, I84M, V88I, F100Y, L101I, T112V, T124N, T125A, K136R, K160R, V201I, T218I, L234I, R269K, D278A  
08/66 08/66 None    V31I, D41N, K42Q, F100Y, L101I, T112V, S119P, T124A, T125A, G134D, K136R, K188R, V201I, Q221S, L234I, D278A  
08/682 08/682 None    D41N, K42Q, I72V, L74I, L101I, T112V, T124N, R187K, G189R, V201I, K215N, L234I, D278A  
08/703 08/703 None   Q95K K14R, V31I, D41N, K42Q, I84M, P90S, L101I, T112V, T124A, T125A, K136Q, V201I, I203M, A205S, I208L, L234I, R269K, D278A G70R 
08/720 08/720 None   E138D K14R, V31I, K42Q, L101I, T112V, T124N, K136Q, V201I, L234I, D256E, D278A  
09/1000 09/1000 None    K14R, L28I, D41N, K42Q, L45Q, F100Y, L101I, K103R, K111R, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, R269K, D278A  
09/1010 09/1010 None   L74M K14R, V32I, L101I, K103R, T112V, T124A, T125A, K136Q, I200L, V201I, I203M, T218I, L234I, D278A  
10/1044 10/1044 None    K14R, L28I, K42Q, I84M, F100Y, L101I, G106A, K111R, T112V, T124A, T125A, K136Q, V201I, A205S, T218S, I220V, L234I, D278A  
10/1050 10/1050 None    D6E, E10D, D41N, K42Q, L74I, L101I, T112V, T124G, T125S, K136Q, K156N, V165I, V201I, T218S, Q221S, L234I, D278A  
10/1051 10/1051 None    V31I, I84M, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, D278A  
10/1253 10/1253 None    K14R, L28I, V31I, V32I, K42Q, L74I, I84M, L101I, T112V, T124A, T125A, I135V, K136Q, I162V, V201I, L234I, D278A  
10/1320 10/1320 None    E10D, V31I, D41N, K42Q, L45Q, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V165I, K188R, V201I, I203M, L234I, R269K, D278A  
10/1400 10/1400 None    K14R, V31I, K42Q, I60V, I72V, I84M, F100Y, L101I, T112V, T122I, T124A, T125A, K127R, V201I, L234I, R269K, D278A  
10/1401 10/1401 None    V31I, K42Q, L101I, G106A, T112V, T124N, T125A, K136Q, K173R, V201I, K211R, L234I, R269K, D278A  
10/507 10/507 None    L28I, K42Q, I84L, F100Y, L101I, K111R, T112V, T124A, T125A, K136Q, K188R, G193E, V201I, I203M, L234I, D253E, D278A  
11C/1248 11C/1248 None    D41N, K42Q, L45Q, P90S, F100Y, L101I, G106A, T112V, T124A, T125A, K136Q, V201I, A205S, L234I, D278A  
11C/1285 11C/1285 None    K14R, V31I, K42Q, L101I, T112V, T124G, T125A, K127R, K136Q, V165I, V201I, L234I, D278A  
11C/1408 11C/1408 None    K42Q, L101I, T112V, T124A, T125A, G134D, V201I, I220V, L234I, D278A  
11C/1439 11C/1439 None    S17N, V31I, K42Q, I72V, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D256E, R269K, D278A  
11C/1441 11C/1441 None    K42Q, L45V, L101I, I113V, T124A, T125A, I135V, V201I, I203M, L234I  
11c/159 11c/159 None    R20K, V31I, D41N, K42Q, I72V, L101I, T112V, T124A, T125A, K136Q, V165I, V201I, T218S, L234I, R269K, D278A  
11C/447 11C/447 None    K14R, L28I, V31I, V32I, K42Q, I60V, I84M, F100Y, L101I, T112I, T124A, T125A, K136Q, I203M, K211Q, L234I, I251L, D278A  
11C/459 11C/459 None   S230R K14R, V31I, K42Q, L101I, T112V, T124A, K136Q, V201I, I220L, L234I, D253E, D278A  
11C/467 11C/467 None    E11D, A23V, D41N, K42Q, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, I220V, L234I, R269K, D278A  
11C/487 11C/487 None    S17N, D41N, K42Q, L45Q, L74I, I84M, F100Y, L101I, G106A, T112V, K136Q, V201I, L234I, D278A  
11C/608 11C/608 None    K7R, K14R, R20K, V32I, D41N, K42Q, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T206S, L234I, D278A  
11N/1130 11N/1130 None    E10D, E13D, L28I, K42Q, L45V, I84M, L101I, K111R, T112V, T124G, T125A, K136Q, V201I, L234I, R269K, D278A  
11N/126 11N/126 None    V31I, D41N, K42Q, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I220V, Q221S, L234I, D278A  
11N/1300 11N/1300 None    K14R, V31I, K42Q, I84M, F100Y, L101I, T112V, T124S, T125V, V165I, I200L, V201I, Q216H, L234I, V260I, R269K, D278A  
11N/1301 11N/1301 None    E10D, E13D, L28I, K42Q, L45V, I84M, L101I, K111R, T112V, T124G, T125A, K136Q, V201I, L234I, R269K, D278A  
11N/1304 11N/1304 None   Q95K D41N, K42Q, I72V, L101I, K111R, T124S, T125A, G134D, K136R, V201I, I203M, L234I, D278A  
11N/1444 11N/1444 None    V31I, D41N, K42Q, L45Q, M50I, L74I, I84M, F100Y, L101I, T112V, T124S, T125A, V201I, K211T, L234I, S255N, R269K, D278A  
11N/1675 11N/1675 None    V31I, K42Q, I60M, I72T, L74I, I84L, L101I, T112V, S119T, T124A, K136Q, E198D, V201I, I217V, T218L, L234I, D278A  
11N/1677 11N/1677 None   G163R V31I, D41N, K42Q, I84M, L101I, T112V, T124A, T125A, G134N, K136Q, M154I, I162V, V165I, V201I, K211R, T218I, L234V, R269K, D278A  
11N/1756 11N/1756 None    K14R, V31I, D41N, K42Q, L45Q, M50T, I60V, F100Y, L101I, G106A, T112V, T124N, T125S, K136Q, V201I, L234I, S255N, R269K, D278A  
11N/584 11N/584 None    V31I, K42Q, L45Q, M50I, F100Y, L101I, T112V, T124N, T125A, K136Q, I141V, V201I, K211R, T218I, L234I, S255N, R269K, D278A  
11N/590 11N/590 None    V31I, D41N, K42Q, M50I, I84M, F100Y, L101I, T112V, T124A, T125A, K127R, G134D, A196P, V201I, L234I, D278A  
12C/155 12C/155 None    E11D, V31I, D41N, K42Q, L45Q, I84L, L101I, T112V, T124A, V165I, S195T, V201I, L234I, D278A  
12C/476 12C/476 None    S17N, L28I, P30A, K42Q, L45Q, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T206S, T218I, L234I, R269K, D278A  
12C/477 12C/477 None    S17N, A21S, L28I, P30A, K42Q, L45Q, L74I, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T206S, T218I, L234I, R269K, D278A  
12C/478 12C/478 None   L74M K14R, V31I, K42Q, L101I, T112V, I113V, T124A, T125A, G163E, V165I, T218I, L234I, D278A  
12C/535 12C/535 None    V31I, K42Q, I84M, F100Y, L101I, T112I, T124A, T125A, K136Q, I203M, L234I, D278A  
12C/537 12C/537 None    K14R, V31I, K42Q, L45Q, I72V, I84M, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, I220V, L234I, D278A  
12C/542 12C/542 None    D6E, E11D, S17N, M50I, L74I, L101I, T112V, T124N, T125A, K136Q, G163E, V201I, T218I, L234I, R269K, D278A  
12N/1755 12N/1755 None    K14R, V31I, D41N, K42Q, L45Q, M50T, L74I, F100Y, L101I, T112V, K136Q, V201I, K211R, Q221S, L234I, S255N, R269K, D278A  
12N/856 12N/856 None    K14R, V31I, V32I, D41N, K42Q, L45Q, I60V, F100Y, L101I, T112V, T124A, T125A, K136Q, K188R, V201I, L234I, R269K, D278A  
DR09/02 DR09/02 None    E10D, V31I, I84M, L101I, T112V, S119P, T124A, K136Q, G163A, V201I, L234I, R269K, D278A  
DR10/04 DR10/04 None   L74M V31I, K42Q, I84M, F100Y, L101I, T112V, T122I, T124A, T125A, V201I, I203M, I208L, L234I, R269K, D278A  
DR10/21 DR10/21 None    K14R, S24N, D25E, V31I, I84M, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, V201I, K211R, L234I, R269K, D278A  
DR11/10 DR11/10 None   L74M V31I, K42Q, I84M, L101I, T112V, T124A, T125A, G134D, K136Q, V201I, I203M, L234I, D278A  
DR11/12 DR11/12 None    K14R, V31I, K42Q, L74I, F100Y, L101I, G106A, T112V, I113V, T124A, T125A, K136Q, V201I, T218S, I220L, L234I, R269K, D278A  
DR11/15 DR11/15 None    V31I, K42Q, L74I, L101I, T112V, T124A, T125A, K136Q, V165I, V201I, I203M, L234I, I251L, D278A  
DR11/19 DR11/19 None    E10D, V31I, K42Q, I84M, L101I, T112V, S119G, T122I, T124N, V201I, L234I, D278A  
DR11/21 DR11/21 None    K14R, R20K, M22L, V32I, V37I, D41N, K42Q, F100Y, L101I, T112V, T124A, T125A, K136Q, V165I, V201I, K211R, L234I, D278A  
DR11/23 DR11/23 None    S17N, V31I, L101I, T112V, S119T, T124A, T125A, K136Q, V201I, L234I, D256E  
DR11/25 DR11/25 None    K14R, K42Q, I84M, L101I, T112V, T124A, T125A, G134D, I135V, V201I, L234I, D278A  
DR11/28 DR11/28 None    S17N, R20K, V31I, K42Q, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218L, I220V, L234I, D256E, D278A  
DR11/35 DR11/35 None    A23V, V31I, L101I, T112V, T124A, T125A, K136Q, V201I, K215N, L234I, R269K, D278A  
DR11/44 DR11/44 None    R20K, V31I, V32I, K42Q, F100Y, L101I, K111R, T112V, T124A, T125A, V201I, T206S, T218L, L234I, D278A  
DR11/50 DR11/50 None    K14R, A21S, V32I, V37I, D41N, K42Q, I60V, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, K211R, Q221S, L234I, D278A  
DR11/60 DR11/60 None   T97A K14R, V31I, K42Q, L45Q, L74I, L101I, T112V, T124A, T125A, K136Q, K188R, V201I, Q221S, L234I, D278A  
DR12/12 DR12/12 None    E11D, V31I, D41N, K42Q, L45Q, M50I, L101I, T112V, T125A, K136Q, I162V, V201I, T218I, I220V, L234I, S255N, R269K, D278A  
DR12/13 DR12/13 None    D41N, K42Q, L45Q, I84M, L101I, T112V, I113V, T124A, T125A, K136Q, V201I, T218L, L234I, D278A  
DR12/18 DR12/18 None    K14R, V31I, I60V, I84M, P90S, L101I, T112I, T124A, T125A, K136Q, I200L, V201I, L234I  
DR12/21 DR12/21 None    D6E, K14R, S17N, V32I, D41N, K42Q, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I220V, L234I, D278A  
DR12/22 DR12/22 None    K14R, V31I, K42Q, I84M, A91T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, R269K, D278A  
VL11/311 VL11/311 None    K14R, K42Q, I72V, F100Y, L101I, T112V, T124G, T125A, K127R, K136Q, L234I, D278A