<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Alessandri-Gradt (2017)
Title HIV-1 non-group M phenotypic susceptibility to integrase strand transfer inhibitors.
Citation J Antimicrob Chemother
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup O
SelectedType Clinical
NumIsolates 36
NumPts 36
Host Human

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
BCF001 BCF001 None    M22L, N27G, V37I, S39N, Q44H, L45I, M50I, C56Y, G59E, I60V, L63I, I72V, L74I, Y83F, A91T, G106A, T112V, S119P, T124A, V126M, G134N, K136Q, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, L234I, N254K, S255G D41P, D207H, T218F, R224Q, K240Q 
BCF002 BCF002 None   L68V M22L, N27G, V37I, Q44H, L45I, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207H, R224Q, K240Q 
BCF003 BCF003 None    M22L, D25E, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63X, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, G134N, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207Q, K240Q 
BCF005 BCF005 None    M22L, N27G, V37I, Q44H, L45I, K46R, M50R, G59E, L63M, L74I, Y83F, G106A, V110I, T112I, I113L, S119P, T124A, T125A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207Q, K240Q 
BCF006 BCF006 None    M22L, N27G, V37I, Q44H, L45I, C56Y, G59E, L63M, L74I, Y83F, G106A, T112I, S119P, T124A, T125A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207Q, R224Q, K240Q 
BCF008 BCF008 None    M22L, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112I, S119P, T124A, V126M, A133T, G134N, K136R, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, A196P, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF009 BCF009 None   L68V M22L, N27G, V37I, S39N, Q44H, L45I, M50T, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112I, S119P, T124A, V126M, A133T, G134N, K136T, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF010 BCF010 None    M22L, N27G, V37I, S39N, Q44H, L45I, A49P, G59E, L63M, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, I208L, K211T, T218L, N222K, L234I, N254K, S255G, D256E D41P, D207Q, K240Q 
BCF011 BCF011 None    M22L, N27G, V37I, Q44H, L45I, G59E, L63M, L74I, Y83F, G106A, T112I, S119P, T124A, T125A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G, D256E D41P, D207Q, K240Q 
BCF013 BCF013 None    M22L, N27G, V37I, Q44H, L45I, G59E, I60V, L63I, I72V, L74I, Y83F, A91T, Y99H, G106A, T112V, S119P, T124A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160A, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207H, K240Q 
BCF057 BCF057 None    M22L, N27G, V37I, Q44H, L45I, G59E, I60V, L63M, L74I, Y83F, G106A, T112V, S119P, T124A, T125A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, T210I, K211T, L234I, N254K, S255G D41P, D207Q, T218F, R224RQ, K240Q 
BCF100 BCF100 None    M22L, N27G, V37I, S39N, Q44H, L45I, M50T, C56Y, G59E, I60V, I72IV, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, I191M, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF101 BCF101 None    R20K, M22L, D25E, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, L68T, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF108 BCF108 None    M22L, N27X, V37I, S39N, Q44H, L45T, M50I, G59E, I60V, L63I, L68T, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF109 BCF109 None   L68V M22L, N27G, V37I, Q44H, L45I, K46R, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, T125A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, L234I, N254K, S255G D41P, D207H, T218F, K240Q 
BCF111 BCF111 None    D25E, F26Y, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF112 BCF112 None    M22L, N27G, V37I, Q44H, L45I, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, G134N, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, T218L, K219Q, L234I, N254K, S255G D41P, D207H, K240Q 
BCF113 BCF113 None   L68I R20K, M22L, D25E, F26Y, N27G, V37I, S39N, Q44H, L45I, M50I, G59E, I60V, L63I, L74I, Y83F, T93S, G106A, T112V, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF120 BCF120 None   L68V M22L, N27G, V37I, Q44H, L45I, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207H, K240Q 
BCF177 BCF177 None   L68V M22L, N27G, V37I, S39N, Q44H, L45I, M50T, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112I, S119P, T124A, V126M, A133T, G134N, K136T, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF178 BCF178 None    N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, L68A, I72V, L74I, Y83F, G106A, T112I, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
BCF183 BCF183 None    R20K, M22L, D25E, N27G, K34KR, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, L74I, Y83F, G106A, T112X, S119P, T124A, T125S, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
MVP5180 MVP5180 None    M22L, N27G, V31I, V37I, Q44H, L45I, M50T, C56Y, G59E, L63M, L74I, Y83F, G106A, T112V, S119P, T124A, T125A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, Q221N, L234I, N254K, S255G D41P, D207Q, K240Q 
RBF125 RBF125 None    M22L, N27G, L28I, V37I, Q44H, L45I, C56Y, G59E, L63M, L74I, Y83F, G106A, T112V, S119P, T124TA, T125A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, K211T, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
RBF130 RBF130 None   L68V M22L, D25E, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112V, S119T, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
RBF189 RBF189 None    M22L, D25E, N27G, V37I, S39N, Q44H, L45I, M50I, L63M, I72V, L74I, Y83F, G106A, T112I, T124A, V126M, G134N, K136Q, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, N222K, L234I, N254K, S255G D41P, D207Q, K240Q 
RBF206 RBF206 None    M22L, N27G, V37I, Q44H, L45I, K46R, G59E, I60V, L63M, L74I, Y83F, G106A, T112I, S119P, T125A, V126M, A133T, K136T, Q137H, S153A, K160S, G163Q, I182V, Y194C, S195T, I200L, V201I, I203M, I204L, T206S, K211T, T218L, N222K, L234I, N254K, S255G D41P, D207Q, K240Q 
YBF16 YBF16 None    M22L, N27G, V37I, Q44H, L45I, K46KR, A49P, G59E, L63M, L74I, Y83F, G106A, T112I, S119P, T124A, V126M, A133T, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G, D256E D41P, D207Q, K240Q 
YBF17 YBF17 None    M22L, D25E, N27G, V31I, V37I, S39N, Q44H, L45I, M50I, G59E, I60V, L63M, L68A, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, G134N, S153A, K160S, G163Q, K173R, S195T, I200L, V201I, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207Q, K240Q 
YBF18 YBF18 None   L68V, G140GE R20K, M22L, D25E, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63M, I72V, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, G134N, K136Q, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, K211T, T218L, L234I, N254K, S255G D41P, E96EK, D207Q, K240Q 
YBF26 YBF26 None    M22L, N27G, V37I, S39N, Q44H, L45T, M50I, G59E, I60V, L63I, L74I, Y83F, G106A, T112V, S119P, T124A, V126M, A133T, G134N, K136R, Q137H, S153A, K160S, G163E, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
YBF32 YBF32 None    R20K, M22L, N27G, V37I, Q44H, L45I, M50I, G59E, I60V, L63I, L74I, Y83F, T93S, G106A, T112V, S119P, T124A, V126M, A133T, G134N, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q 
YBF35 YBF35 None    M22L, N27G, V37I, A38V, S39N, Q44H, L45M, G59E, I60V, L63M, L74I, Y83F, G106A, T112I, S119P, T124A, T125A, V126M, A133T, S153A, K160S, G163Q, S195T, I200L, V201L, I204L, T206S, K211T, T218L, L234I, N254K, S255G D41P, D207Q, K240Q 
YBF37 YBF37 None   T97A M22L, N27G, V31VL, V37I, Q44H, L45I, M50I, I60V, L63M, I72V, L74I, Y83F, G106A, V110I, T112V, I113L, S119T, T124A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160S, G163Q, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, N222K, L234V, N254K, S255G, D256E D41P, D207Q, R224Q, K240Q 
YBF38 YBF38 None    M22L, N27G, V37I, S39N, Q44H, L45I, M50T, C56Y, G59E, I60V, L63I, I72V, L74I, Y83F, G106A, T112V, S119X, T124A, V126M, A133T, G134N, K136R, Q137H, S153A, K160S, G163Q, K173R, I182V, I191M, S195T, V201I, I204L, T206S, K211T, N222K, L234I, N254K, S255G D41P, D207Q, T218F, R224Q, K240Q, Q252QL, K258KN 
YBF39 YBF39 None    M22L, N27G, V37I, S39N, Q44H, L45I, M50I, G59E, I60V, L63M, L68T, I72V, L74I, Y83F, G106A, V110VI, T112I, S119P, T124A, T125A, V126M, A133T, G134N, K136Q, Q137H, S153A, K160S, G163Q, K173R, I182V, S195T, I200L, V201I, I204L, T206S, K211T, T218L, N222K, L234I, N254K, S255G D41P, I203T, D207Q, K240Q