<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Bradley-Stewart (2017)
Title HIV-1 integrase inhibitor resistance among treatment nave patients in the West of Scotland.
Citation J Clin Virol
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 91
NumPts 91
Subtype B, C, A, CRF01_AE, G, F, CRF02_AG

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
WoSSVC_INT1 WoSSVC_INT1 None    E10EG, D25E, I72V, F100Y, L101I, T112I, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT10 WoSSVC_INT10 None    E10ED, Y15YF, S17SN, D25E, L45I, I72V, I84M, F100Y, L101I, T112V, T124A, T125A, K188KR, V201I, T218I, L234I, D256E, A265V, D278A, S283X  
WoSSVC_INT11 WoSSVC_INT11 None    K14R, L101I, T112V, T124A, T125A, G134N, K136T, G193E, V201I, T206S, T218L, L234I, D256E, R269K, D270H S283G, D288N 
WoSSVC_INT12 WoSSVC_INT12 None   V151I, G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I, D278A S283G 
WoSSVC_INT13 WoSSVC_INT13 None    V31I, T124A, K156N, V201I, D256E  
WoSSVC_INT14 WoSSVC_INT14 None    E11D, V32VI, I72V, I73IV, T112V, S119T, T124A, T125A, V126M, G134N, I135V, K136R, D167E, G193E, V201I, I203M, I208L, L234I S283G, D286N 
WoSSVC_INT15 WoSSVC_INT15 None    K7R, E11ED, P30S, V31I, V32VI, V37VI, D41DN, I60V, L101I, K111A, I113IV, S119P, T122X, T124N, K156KR, I208L, T218TS, N222NK, S230N, D232DE, L234LI, D256E, M275MV  
WoSSVC_INT16 WoSSVC_INT16 None    K7KR, S17N, R20K, L101I, K103R, K111A, T124N, I208L, I220L, Y227F, A265V  
WoSSVC_INT17 WoSSVC_INT17 None    K14KR, V31I, I84IV, A91AV, L101I, T112V, I113V, T124A, T125A, G134D, D167E, V201I, I220L, L234I, R269K, D278A S283G, R284G 
WoSSVC_INT18 WoSSVC_INT18 None    E11D, S17T, L101I, T112TI, I113V, S119R, T124N, T125S, S153SA, G163D, H171HY, V176VL, K211R  
WoSSVC_INT19 WoSSVC_INT19 None    K14R, V31I, S39SN, L45Q, S57N, L101I, T112I, T124N, G134S, K136T, I182IV, V201I, T206S, N222K, L234I, S255N, D256E  
WoSSVC_INT2 WoSSVC_INT2 None    E10D, E11D, A21T, I72V, L101I, K103R, S119P, T122I, D167E, T218I, D256E N117NK 
WoSSVC_INT20 WoSSVC_INT20 None    T112TI, T125X, V126M, K156KN, V201I R284RG 
WoSSVC_INT21 WoSSVC_INT21 None    E10D, E11D, A21T, I72V, L101I, K103R, S119P, T122I, D167E, D256E  
WoSSVC_INT22 WoSSVC_INT22 None   G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, M154MI, D167E, K188R, V201I, T218I, L234I E48EK, S283G 
WoSSVC_INT23 WoSSVC_INT23 None    K14R, S24N, V31I, M50MI, L101I, T112V, I113IV, T124N, T125A, K136Q, V201I, K211KR, T218TI, L234I, D278A S283G, R284RG 
WoSSVC_INT24 WoSSVC_INT24 None    E11D, K14R, S17T, S39C, L101I, G193D, V201I, D279G  
WoSSVC_INT25 WoSSVC_INT25 None    D25E, I72V, F100Y, L101I, T112X, T124TA, T125A, K136Q, D167E, I182IV, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT26 WoSSVC_INT26 None    E11ED, K14KR, S17SN, D25E, I72V, I84IL, F100Y, L101I, K111R, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT27 WoSSVC_INT27 None    S17N, R20K, C56Y, I72V, T124A, T125A, I135V, K188R, T206S, I220V, L234I, I251L, D256E C43C*, V281M 
WoSSVC_INT28 WoSSVC_INT28 None    I72V, V110I, I113V, T124A, M154L, R187K, V201I, K211R S283G 
WoSSVC_INT29 WoSSVC_INT29 None   G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT3 WoSSVC_INT3 None  T66TI G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT30 WoSSVC_INT30 None    D25E, I72V, I84IM, L101I, T112TI, T124A, T125A, K136Q, D167E, K188KR, V201I, T218I, L234I E35EK, S283G 
WoSSVC_INT31 WoSSVC_INT31 None    E11D, K14KR, S24N, V31I, V32I, L45LI, L101I, K111Q, T112A, S119P, T122I, S230N  
WoSSVC_INT32 WoSSVC_INT32 None    S17N, V31I, T124TA, V201VI, T210A, I220L, D253E  
WoSSVC_INT33 WoSSVC_INT33 None    K7KQ, D25E, V31I, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, L234I, A265V, R269K, D278A S283G 
WoSSVC_INT34 WoSSVC_INT34 None    S17C, L45V, L101I, T122I, T124N, G163E, K173R, I182V, H183HY, I220L G82GR, E85EK, G192GR, D288N 
WoSSVC_INT35 WoSSVC_INT35 None    D25E, I72V, F100Y, L101I, T112I, S119G, T124A, T125A, K136Q, D167E, K188R, V201I, I203V, T218I, L234I Q177QP, S283G 
WoSSVC_INT36 WoSSVC_INT36 None   G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT37 WoSSVC_INT37 None    E10D, E11D, D25E, V31I, M50T, L101I, T112V, S119T, K136Q, V201I, L234I, R269K, D278A S283G 
WoSSVC_INT38 WoSSVC_INT38 None    K14R, V31I, L101I, T124S, T125A, G134N, I135V, K136T, K173R, V201I, T206S, Q216R, K219N, L234I, D256E, I268L S283G 
WoSSVC_INT39 WoSSVC_INT39 None    E11D, R20K, S24N, L28I, S39M, M50I, I72V, L101I, S119P, T124N, I135V, V201I, L234I S283G 
WoSSVC_INT4 WoSSVC_INT4 None   V151VI, G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I, D278DA S283G 
WoSSVC_INT40 WoSSVC_INT40 None    S17N, R20K, I72V, S119ST, T122TI, T124A, T125A, I135V, K188KR, T206S, L234I, I251L, D256E V281M 
WoSSVC_INT41 WoSSVC_INT41 None    K7KQ, D25E, N27D, V31VI, S39SC, L45LQ, M50I, I72V, Q95X, F100Y, L101I, T112X, T124A, T125A, I135IV, K136Q, V201I, I203IM, T206S, D207DE, I208IM, T218I, L234I, A265AV, D278DA S283G, D286DN 
WoSSVC_INT42 WoSSVC_INT42 None    E10D, E11D, A21T, I72V, L101I, K103R, S119P, T122I, D167E, D256E  
WoSSVC_INT43 WoSSVC_INT43 None    S24D, D25E, S39C, L45V, S119P, I191IM, S230N  
WoSSVC_INT44 WoSSVC_INT44 None    S17N, R20K, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, K211R, T218I, L234X, V249VL, D278DN A276AE, S283G 
WoSSVC_INT45 WoSSVC_INT45 None    K14KR, S17SN, D25E, I72V, F100Y, L101I, T112X, S119X, T122TI, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT46 WoSSVC_INT46 None    N27NS, V31I, M50I, E96D, T112V, T124N, T125A, V126M, K136Q, V201I, K211R, R224RW, D256E S283G 
WoSSVC_INT47 WoSSVC_INT47 None    V88I, Q95P, L101I, T124N, K156N, G193E, R228RG, D279G D288N 
WoSSVC_INT48 WoSSVC_INT48 None    D6E, M50I, L101I, T112V, T124A, K136T, H171HY, K188KR, G193GE, V201I, I208L, D232E, L234I, D256E, I268L S283G 
WoSSVC_INT49 WoSSVC_INT49 None    E11D, S17T, A23V, V31I, M50MI, I72V, L101I, K111T, I135V, V201VI D286N 
WoSSVC_INT5 WoSSVC_INT5 None   L74LM, G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT50 WoSSVC_INT50 None    K14R, D25E, V31I, L45Q, L101I, T112V, T124A, T125A, G134S, K136Q, V201VI, T206S, T218I, L234I S283G, D286N 
WoSSVC_INT51 WoSSVC_INT51 None    E10D, D25E, I72V, L101I, T112I, S119SG, T122TI, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT52 WoSSVC_INT52 None   V54I E11D, S24N, I72IV, L101I, I113V, S119P, T122I, T125TA, I203IL T206TI, E212ED, Q285P 
WoSSVC_INT53 WoSSVC_INT53 None    E11D, A21AT, S24N, V31I, V32I, L101I, K111Q, T112A, S119P, T122I, T124N, F139FL, V201VI, S230N  
WoSSVC_INT54 WoSSVC_INT54 None    E11D, S24N, V31I, L101I, S119P, T122I, T124A, T125S, K136N  
WoSSVC_INT55 WoSSVC_INT55 None    S39C, I72V, L74I, T122I, T124N, T125A, V201I, N254Q Q164R 
WoSSVC_INT56 WoSSVC_INT56 None    S39C, I72V, L74I, T122I, T124N, T125A, V201I, N254Q  
WoSSVC_INT57 WoSSVC_INT57 None    E11D, K14R, R20K, L101I, T112V, I113V, S119P, T125A, K127R, I135V, D167E, G193D, S195T, V201I, T206S, T218I, L234I, R269K, K273Q, D278N G149GE, S283G, D286N 
WoSSVC_INT58 WoSSVC_INT58 None    E10EA, E11ED, L45LI, Q95P, L101I, T122TI, T124N, K156N, G193E, D279G D288N 
WoSSVC_INT59 WoSSVC_INT59 None    D6E, E11D, S24N, G59E, L101I, T112A, V201I, T206S, E212A, Q216H, K219N  
WoSSVC_INT6 WoSSVC_INT6 None    D25E, I72V, F100Y, L101I, T112I, T124TA, T125A, K127KR, K136Q, D167E, I182IV, K188KR, V201I, T218I, L234I Q214Q*, S283G 
WoSSVC_INT60 WoSSVC_INT60 None    K14R, R20K, M50MR, I72IV, L101I, T112V, I113V, S119P, T122I, T124N, T125A, I135V, D167E, G193D, S195T, V201I, T206S, T218I, L234I, R269K, K273Q, D278N A276AV, S283G, D286N 
WoSSVC_INT61 WoSSVC_INT61 None    E11D, K14R, S24A, L28I, L45V, S119G, T122I, T124N, T125A, L234F  
WoSSVC_INT62 WoSSVC_INT62 None    E11D, S24N, V31I, V32I, L101I, K111Q, T112A, S119P, T122I, T124N, F139FL, V201VI, S230N V281VM 
WoSSVC_INT63 WoSSVC_INT63 None    S17N, V31I, V32I, E35EQ, S39SN, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I203M, T218I, N222NT, L234I, R269K, D278A S283G 
WoSSVC_INT64 WoSSVC_INT64 None    E11D, S17N, A21S, P30S, I60V, L101I, T112TI, T124S, T125A, K136Q, V201I, T218I, L234V, D256E D286N 
WoSSVC_INT65 WoSSVC_INT65 None    K14KR, D25E, L28I, L45LQ, I72V, I84IM, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, L234I S283G 
WoSSVC_INT66 WoSSVC_INT66 None    K14KR, D25E, L28I, S39C, M50I, I72V, L101I, K111T, S119T, S123C, T124N, V165I, D167E, Y227F, S230N, L234V A282AV, S283SR 
WoSSVC_INT67 WoSSVC_INT67 None    K14KR, R20RK, D25E, I72V, F100Y, L101I, T112V, S119ST, T124A, T125A, K136Q, D167E, V201I, T206S, T218I, L234I S283G 
WoSSVC_INT68 WoSSVC_INT68 None    E11D, S17C, I72V, T124A, T125A, K156N, V165I  
WoSSVC_INT69 WoSSVC_INT69 None    E11D, K14R, L28I, V31VI, V32I, Q53K, L101I, K111X, T112I, T124N, T125M, V201I  
WoSSVC_INT7 WoSSVC_INT7 None    K14R, S17T, M50I, L101I, T112X, T124A, T125A, G134N, K136N, K156N, E157Q, V201I, T206S, Y227F, L234I, S255N, D256E S283G 
WoSSVC_INT70 WoSSVC_INT70 None    E11D, L28I, V37I, S39C, L101I, T125A, I135V, V201I, K215N  
WoSSVC_INT71 WoSSVC_INT71 None    I72V, L101I, M154MI, G163E, K173R, I182V, A205S  
WoSSVC_INT72 WoSSVC_INT72 None    D25E, I72V, F100Y, L101I, K111KR, T112I, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, S230SN, L234I S283G 
WoSSVC_INT73 WoSSVC_INT73 None    D25E, I72V, F100Y, L101I, T112I, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I R263RG, S283G 
WoSSVC_INT74 WoSSVC_INT74 None   G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, I191IM, V201I, T218I, L234I S283G 
WoSSVC_INT75 WoSSVC_INT75 None    K14R, D25E, I72V, I84IM, F100FY, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218TI, L234I S283G 
WoSSVC_INT76 WoSSVC_INT76 None   L68LV K7Q, E11D, S24N, D25E, V31I, M50I, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T210V, L234I, R269K, D278A S283G, D288N 
WoSSVC_INT77 WoSSVC_INT77 None    E11D, K14R, S24N, M50MR, I113IV, T125A, Q177L, V201I  
WoSSVC_INT78 WoSSVC_INT78 None    D25E, I72V, F100Y, L101I, T112I, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT79 WoSSVC_INT79 None    S17N, P30S, L45V, I60V, V77A, L101I, T112V, T124S, T125A, K136Q, V165I, V201I, A205S, K211R, L234V, D256E T97TI, S283G, D288DG 
WoSSVC_INT8 WoSSVC_INT8 None   G163R K14R, S17N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT80 WoSSVC_INT80 None    K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, V126M, G134N, I135V, K136R, V165I, D167E, V201I, L234I S283G 
WoSSVC_INT81 WoSSVC_INT81 None    D25E, I72V, F100Y, L101I, T112I, T124A, T125A, K136Q, D167E, K188R, V201I, T218I, L234I S283G 
WoSSVC_INT82 WoSSVC_INT82 None    K7R, V31I, L101I, K111KR, T124A, G163GE, V201I  
WoSSVC_INT83 WoSSVC_INT83 None    E11D, S17N, V31VI, I84M, L101I, T112V, S119X, T125TA, K136Q, V201I, K211R, L234I, D278A V281VM, S283G, R284RG 
WoSSVC_INT84 WoSSVC_INT84 None    E11D, V31VI, V37I, S39C, I72V, L101I, I113V, S119P, T122I, T125A, I200X, V201I, D232E V32VG 
WoSSVC_INT85 WoSSVC_INT85 None    E11D, A21T, V31VI, V32VI, I72V, T112V, S119P, T124Q, T125A, V126L, G134N, I135V, K136R, V165VI, D167E, V201I, K215KN, L234I S283G 
WoSSVC_INT86 WoSSVC_INT86 None    E11D, L28I, V37I, S39C, L101I, S119P, T122I, T125A, V201I, Q216H, S230N V281VM, S283G 
WoSSVC_INT87 WoSSVC_INT87 None    D25E, V31I, I72V, I84M, V88I, T112V, S119P, T124N, T125A, G134GD, K136Q, V201I, T210TI, I220V, L234I, D278A  
WoSSVC_INT88 WoSSVC_INT88 None    E11D, S24N, V31I, M50T, L101I, S119G, T122I, T124N, G193E, V201I  
WoSSVC_INT89 WoSSVC_INT89 None    K14R, V32I, I72V, L74X, T112V, I113V, T124A, T125A, V126M, G134N, K136Q, V165VI, V201I, T206S, I220V, L234I V281M, S283G, D286N 
WoSSVC_INT9 WoSSVC_INT9 None    T124A, K156N, V201I, D256E D288DN 
WoSSVC_INT90 WoSSVC_INT90 None    E11D, S24N, L101I, S119G, T125V, M154I, K211R  
WoSSVC_INT91 WoSSVC_INT91 None    V31I, A91E, L101I, T112A, S119R, T124N, T206S, E212A, Q216H, K219N, S230N