Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Crawford (2014)
Title Occurrence of etravirine/rilpivirine-specific resistance mutations selected by efavirenz and nevirapine in Kenyan patients with non-B HIV-1 subtypes failing antiretroviral therapy.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 14
NumPts 14
Subtype A, B, D


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
SN-031065 SN-031065 AZT, 3TC EFV   K43Q, K49R, V60I, K122E, D123S, I135T, E138G, K166KR, K173L, Q174K, V179I, T200E, I202V, Q207A, R211S, V245E  
SN-031169 SN-031169 AZT, 3TC NVP M41L, T69S_XS, V75M, F77FL, M184V, L210W, T215F K101E, V108I, G190A T39E, V60I, K64KR, D86E, W88C, I94IL, A98S, D121Y, K122E, E138A, K173A, Q174K, D177E, V179I, G196E, Q207D, R211K, L228H, V245Q  
SN-031177 SN-031177 TDF, 3TC EFV K70R, M184V K103N, V108I T39L, V60I, K64KR, V106VI, D121H, K122E, I135T, E138EQ, K173S, Q174K, I178L, V179I, T200A, Q207A, R211S K220M 
SN-031209 SN-031209 TDF, 3TC NVP  K101E, E138K T39L, V60I, K104R, K122E, I135L, I142R, K166R, R172K, I178V, T200Q, Q207G, R211K, V245K T84I, F124Y, P140L, G141Y, R143DY, Y144G, Q145K, Y146G, N147R, V148K, K154N_M*, G155S, P157C, N175S 
SN-042020 SN-042020 AZT, 3TC EFV D67N, K70R, M184V, K219Q V108I S48ST, K49R, V60I, K101Q, D121H, K122E, D123S, E138A, K166Q, E169D, K173A, Q174K, D177E, I178L, V179I, T200A, Q207A, Y232H, V245Q  
SN-042062 SN-042062 3TC, D4T EFV   S48E, V60I, E138A, K173L, Q174K, I178M, V179I, G196E, E203Q, Q207D, R211S, V245E  
SN-042066 SN-042066 TDF, 3TC EFV K70R, M184V K103N, V108I T39L, V60I, K64KR, D121H, K122E, I135T, E138EQ, K173S, Q174K, I178L, V179I, T200A, Q207A, R211S  
SN-062054 SN-062054 AZT, 3TC EFV   T39N, D123S, E138EA, K173S, D177G, V179I, I202V, Q207A, R211S, V245Q  
SN-062060 SN-062060 AZT, 3TC EFV K70E, M184V, K219R K103N, P225H, K238T V60I, D121H, K122E, D123S, I135T, E138G, K173S, Q174K, D177E, T200A, Q207A, R211S, L228R, V245A  
SN-072002 SN-072002 3TC, D4T EFV D67DN, K70R, M184V, T215TI, K219EQ L100I, V179D K49KR, V60I, K103R, K122E, I135R, E138A, D177E, I178L, T200E, Q207E, L228LR, V245I  
SN-072012 SN-072012 AZT, 3TC NVP M184V  K122E, I135T, E138A, K173S, Q174K, D177E, I178V, V179IT, T200A, I202V, Q207D, R211S, F214L, V245E  
SN-072075 SN-072075 TDF, 3TC NVP A62AV, V75VI, M184V, K219KE K101KE, Y181C K49R, I50V, K70X, V90VI, D121Y, K122E, E138EG, V189VI, I202V, Q207KT, R211K, H221HY, L228LR, P243T, V245K  
SN-082031 SN-082031 TDF, 3TC NVP  E138K E40D, V60I, K122E, D123N, I142V, K173S, Q174K, D177E, V179T, T200A, I202V, Q207T, R211N, V245Q  
SN-092085 SN-092085 TDF, 3TC EFV M184DG Y188IMV, M230*LS V60I, K122E, D123N, I135T, E138A, I142V, F171L, Q174K, P176K, D177K, V179T, Q182*, G190X, D192X, E194EK, I202V, Q207A, R211S, F214L, P225T, P243T, V245K R72RG, G155R, R172E, N175K_X, I180T, Y183*S, D186H, L187Y, V189LR, L193FI, R199RS, L209LI, K219K*, K220KN, K223K*IL, W229L