<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Bertine (2015)
Title High level of APOBEC3F/3G editing in HIV-2 DNA vif and pol sequences from antiretroviral-naive patients.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 43
NumPts 43
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
001006_CNA 001006_CNART None None I75IL  K82R, V135T, M138A, K223KR, Q228QR, D250E, S272P, K277KR V2I, R78RK, S107T, I108V, A134S, C232Y, Y317C 
004011_CNA 004011_CNART None None N69ND I181IV K28R, K64KR, K82KR, V135T, M138A, P176PS, K200KR, F227Y, D250E, I251R, S272P, K275R, K277R T11AV, R20RK, P51S, S107T, I108V, A134S, V167I, C232Y, L244I 
005010_CNA 005010_CNART None None  I181IV K28KR, K35KR, K82R, E122PT, D123DN, M138A, Y162YH, K200R, G211GDNS, D250E, S272P V2I, S107T, I108V, H121D, A134S, V178VI, C232Y, L244I, Y317C 
008007_CNB 008007_CNBRT None None   I5V, L21I, K22R, T27S, K28KR, K35KR, K43KR, K66R, K104R, E122P, D123N, M138A, E169D, P176S, K200R, G211D, L212M, D218E, D250K, I251V, Y271F, S272P, K277R, L279I, R284K, T290A, E304Q, S311E, Y317S, E322G, E324P, I329V, G334A, H335N, E344G, K347R I8V, K9KE, T11EK, R20K, E32L, I90V, K102D, I108V, H121D, A134S, V135I, T163S, Q166K, L180I, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, I270L, Q320K, E321EG, K323IV, S332N, Q333L, E345N, I348MV 
008010_CNA 008010_CNART None None   A3T, I5M, Q46QR, T58S, K64R, K103R, H121Y, Y162H, K200KR, D218E, D250DEKN, I251IATV, V254VI, S272P, K277KR K4R, K13R, Q23QR, S107T, I108V, A134S, C232Y, L244I, K307R, S311D 
008014_CNA 008014_CNART None None I75IK, F77L, M184MV  K4N, K22R, K35Q, K43KR, K104R, V111VI, V135T, M138A, E139Q, Y162H, F214FL, F227Y, Q228QR, D250E, I251IGRV, S272P K9KR, R20RK, Q23QR, E49IV, T58TA, I63IN, R78E, E79K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317C 
008017_CNA 008017_CNART None None   I5V, V10I, T11M, K22R, K35E, K43R, K64R, K104R, D123N, M138A, K173KR, N175NH, P176PQ, K200KR, F227Y, Q228R, M230MI, D250E, I251V, S272P, R284K V2I, R20K, P51PS, S107T, I108V, H121D, A134S, E139T, Q166K, L180I, I189V, G195D, C232Y, W239W*, L244I 
008025_CNA 008025_CNART None None   E6Q, K22R, K43R, K66KR, K68R, D86E, F87FL, K104R, V111I, M138A, G211GS, F227Y, Q228QR, D250E, I251V, S272P, K277R T11V, R20K, S107T, I108V, A134S, V167I, V178VI, G195D, V201A, G213GR, C232Y, L244I, W266W* 
009017_CNB 009017_CNBRT None None   T11R, L21I, K22R, T27S, K35R, T58S, K66R, D86E, D123DN, M138A, E169D, I179T, T194N, K200R, G211N, L212M, D218E, D250E, I251V, S272P, K277R, L279I, E304Q, S311E, Y317S, E322G, E324P, I329V, G334A, H335N, E344G I8V, R20K, E32L, I90V, K102S, S107T, I108V, H121D, E122S, Q126P, A134S, I145L, T163S, R165G, Q166K, P176N, L180I, I189V, G195D, L203S, C232Y, T237K, L244I, Q248E, G262R, I270L, R284M, Q320K, K323V, S332N, Q333L, E345D 
009031_CNB 009031_CNBRT None None   I5V, L21I, K22R, T27S, K66R, K102E, K104R, E122P, M138A, E169D, A174AT, P176S, G211D, D218E, D250E, I251V, Y271F, S272P, K277R, L279I, E304Q, S311E, Y317S, E322G, E324P, I329V I8V, T11KN, R20K, E32L, I90V, I108V, H121D, A134S, V135I, T163S, Q166KR, L180I, T194S, G195D, L203S, L212MV, C232Y, T237K, L244I, Q248E, I270L, R281K, Q320K, K323I 
009032_CNB 009032_CNBRT None None  I181V T11R, L21I, K22R, T27S, K66R, D86E, K102E, K104R, E122P, M138T, E169D, K173KR, I179T, K200R, G211D, L212M, D218E, Q228K, K243R, D250E, Y271F, S272P, K277R, L279I, R284K, E304Q, S311E, Y317S, E322G, E324P, I329V, G334A, H335N, Y339YD, E344G, K347R, K350R I8V, R20K, E32L, I90V, S107T, I108V, I118V, H121D, A134S, T163S, R165G, Q166K, P176DY, L180I, I189V, T194S, G195D, C232Y, T237K, L244I, Q248E, I251S, I270L, L303F, Q320K, K323I, S332N, E345N 
009041_CNA 009041_CNART None None   E6DN, K22KR, E36EK, E39K, N69S, D86E, K103R, V111I, M138A, Q166N, P176S, I179T, K200R, F227Y, K243R, D250E, I251V, S272P, K277R, R284K, K331R, G334D, H335N, I341V, E344G K4KR, D17DN, G18GE, R20K, E48K, W71WG, R78RK, V83A, S107T, I108V, Q126K, L132I, A134S, L180I, G195D, C232Y, V263I, M287K, T288A, Y317C, S332N 
009042_CNB 009042_CNBRT None None   I5V, K22R, T27S, K35R, E48Q, T58S, K66R, D86E, K103R, K104R, V111I, E122P, D123E, R125K, M138A, R165A, I179T, G211N, L212M, D218E, D250E, I251V, Y271F, S272P, L279I, T290A, E304Q V2I, I8V, K9R, T11K, R20K, E32L, I90V, K102S, I108V, H121D, A134S, I145L, K147N, T163S, Q166K, P176N, L180I, I189V, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, I270L 
012066_CNA 012066_CNART None None   I31IV, K82R, M138A, P176PS, L196M, E207EG, D250E, I251V, S272P, G334D, H335N S107T, I108V, A134S, V135I, Q151QH, V178VI, L180I, R193RK, C232Y, V263I, R281RK, G285GE, Q294QK, Y317H 
012078_CNB 012078_CNBRT None None   I5L, T11Q, L21I, K22KR, T27S, K35R, K64KR, K66KR, K102E, K104R, E122P, M138A, E169D, A174T, P176S, K200R, G211N, D218E, Q228R, K238KR, D250E, I251V, Y271F, S272P, L279I, R284K, L303M, E304Q I8V, R20K, E32L, I90V, S107T, I108V, I118V, H121D, A134S, V135VAIT, I145IT, T163TS, Q166K, L180I, T194S, G195D, L203S, L212IM, C232Y, T237K, L244I, Q248E, I270L 
012081_CNA 012081_CNART None None K70KQ  I5V, K22R, K43R, D86E, K104R, L109I, H121Y, D123DE, M138A, I145V, Y162H, K173KR, K200R, F227Y, Q228QKR, K249R, D250E, I251V, S272P R20K, T84TI, S107T, I108V, A134S, L180I, G195D, C232Y, L244I, M287L 
012100_CNA 012100_CNART None None E219D  T11TM, K22R, K64R, D86E, K104R, M138A, K173R, F227Y, Q228R, D250E, I251V, K277R R20K, P51S, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, S272L, K307R, Y317H 
012101_CNA 012101_CNART None None K70KQ  V10I, T11A, K22R, K43R, K103R, K104KR, M138A, Y162H, N175H, F227Y, Q228R, D250E, S272P, K277R R20K, S107T, I108V, Q126P, A134S, L180I, G195D, C232Y, L244I, K307R, Y317H 
013049_CNB 013049_CNBRT None None  I181V L21I, T27S, K66R, K102E, K103KR, K104R, E122P, E169D, P176S, I179T, K200R, G211D, L212M, D218E, Q228K, D250E, I251N, Y271F, S272P, K277R, L279I, R284K, E304Q K4KR, I8V, T11K, R20K, E32L, I90V, S107T, I108V, I118V, H121D, M138I, T163S, R165G, Q166K, L180I, I189V, T194S, G195D, C232Y, T237K, L244I, Q248E, I270L, L303F 
013050_CNA 013050_CNART None None   K22R, K28R, K43R, K104R, M138A, K173R, K200R, K243R, D250E, I251V, S272Q, K277R R20K, Q85P, S107T, I108V, A134S, T163M, V167I, G195D, C232Y, L244I, I270L, Y317C 
016002_CNB 016002_CNBRT None None D67DE F227L L21I, T27S, K35R, K66KR, D86E, K102E, K104R, V111I, E122P, M138A, I145V, E169D, P176S, G211N, L212M, D218E, Q228R, K240KR, D250E, I251V, Y271F, S272P, K277R, L279I, R284RK, E304Q, S311E, Y317S, E322G, E324P, I329V V2M, I8V, T11EK, R20K, E32L, I90V, S107T, I108V, I118IV, H121D, Q126P, A134S, V135VI, K147T, T163S, R165G, Q166K, L180I, I189IV, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, A268S, I270L, R281K, Q320KR, K323V, S332N, Q333L 
018003_CNA 018003_CNART None None   V10I, T11M, K22R, K104R, M138A, K200R, K223KR, F227Y, Q228H, D250E, I251V, S272P, E291D R20K, S107T, I108V, E122K, A134S, V167I, L180I, G195D, C232Y, L244I, A267V, R281K, M287L 
018019_CNA 018019_CNART None None   T11A, K82R, D86E, M138A, D218E, D250E, I251V, S272P, K277R K4R, S107T, I108V, A134S, K147T, C232Y 
018023_CNA 018023_CNART None None   V10I, T11TA, K22R, K28KR, K35KR, M138A, Y162H, P176Q, K200KR, G211S, F227Y, Q248H, K249KR, D250E, I251V, S272P R20K, S107T, I108V, A134S, L180I, T194TS, G195D, L203LM, C232Y, L244I, K286R, Q294QR 
018024_CNA 018024_CNART None None   E6Q, K22R, K43KR, K104R, M138A, K200R, F227Y, D250E, I251T, S272P, L279I, E297ED K16KR, R20K, S107T, I108V, A134S, V167I, L168I, G195D, C232Y, L244I, M287L, Y317H 
018034_CNA 018034_CNART None None M184MI  E39EK, V135VL, M138A, Y162YH, K200KR, D218DG, M230MI, D250E, L260LI, S272P, R284K K4R, P51S, R105RK, S107T, I108V, E122EK, Q126QP, A134S, W229W*, C232Y, L244LI, W252W*, W266W*, I270L, R281K, G285GR 
018040_CNA 018040_CNART None None   K22R, D86E, K104R, V135T, M138A, Y162H, F227Y, Q228H, W229*, D250E, I251V, S272P, K323E, I329V, G334D, H335N T11K, R20K, P51S, S107T, I108V, A134S, K147R, V167I, L180I, G195D, C232Y, L244I, K307R, Y317H, S332D 
026007_CNA 026007_CNART None None D67DG I181V V10I, K28KR, I31IV, K43R, V111I, V135T, M138A, K200R, D250E, I251V, S272P V2A, R20K, I90V, S107T, I108V, E122EK, A134S, V167I, G195N, V201L, C232Y, L244I, Q294K 
045005_CNB 045005_CNBRT None None F77FL I181V L21I, K22R, T27S, K66R, K102E, K103KR, K104R, E122P, M138T, E169D, I179T, T194N, K200R, G211D, L212M, D218E, Q228K, D250E, Y271F, S272P, K277R, L279I, R284K, E304Q I8V, T11K, R20K, E32L, M41MI, R78REGK, E79EK, I90V, I106IT, S107T, I108V, I118IV, H121D, A134S, T163S, R165RG, Q166KR, P176DGNS, L180I, I189V, G195D, C232Y, T237K, L244I, Q248E, I251S, I270L, R281K, L303F 
045008_CNA 045008_CNART None None   I5IMV, K22KR, K28KR, M138A, Y162H, P176Q, K200KR, G211S, F227Y, Q248H, K249KR, D250E, I251V, S272P R20RK, S107T, I108V, A134S, L180I, T194TS, G195D, L203LM, C232Y, L244I, K286R 
045009_CNA 045009_CNART None None K70KQ  T11M, K22R, K103R, K104R, M138A, Y162H, P176Q, I179T, K200R, F227Y, K249KR, D250E, S272P R20K, P51S, T53S, R105RK, S107T, I108V, H121*CWY, L180I, G195D, C232Y, L244I, L298LI, S311G 
045012_CNB 045012_CNBRT None None   I5V, L21I, K22R, T27S, K28KR, K66R, K104R, E122P, D123N, M138AT, E169D, P176S, I179IT, K200KR, G211D, L212M, D218E, K249R, D250E, I251V, Y271F, S272P, K277R, L279I I8V, K9KE, T11EK, R20K, E32L, T53TA, I90V, K102D, I108V, H121D, A134S, V135VI, T163S, Q166K, L180I, I189IV, T194S, G195D, L203AS, C232Y, T237K, L244I, Q248E, I270L, R281RK 
048012_CNA 048012_CNART None None   I5V, P14PS, K28R, K64R, K82R, D123DN, M138A, K200R, D250E, S272P, L289LI, E291ED I8V, R20K, R105RK, S107T, I108V, I118V, A134S, V135I, C232Y, T237TNS, L244LI, Q294QK, K307R 
049007_CNA 049007_CNART None None F77L I181V D123G, M138A, M230MI, D250E, S272P E32EK, R78E, I94N, S107T, I108V, E122EK, A134S, V167I, L203M, C232Y, R281K, K307R 
049008_CNB 049008_CNBRT None None  I108IV T11Q, L21I, K22R, T27S, K28KR, A50AV, T58S, K66R, D86E, E122P, M138A, E139EK, E169D, I179T, K200R, G211N, L212M, D218E, D250E, I251IV, Y271F, S272P, L279I V2VIM, K4KR, I8V, R20K, E32L, I90V, K102S, S107T, I118IV, H121D, A134S, I145FL, T163S, Q166K, P176N, L180I, I189V, T194S, G195DN, L203S, C232Y, T237K, L244I, Q248E, A267AG, A268AV, I270L, E291EG, E304HQ 
049009_CNB 049009_CNBRT None None F77L  I5IV, D17DG, D86E, M138A, D218E, D250E, I251T, S272P K4R, R20RK, Q85P, S107T, I108V, A134S, V135I, C232Y 
052004_CNA 052004_CNART None None   I5IV, V10VI, K22R, D86E, K104R, M138A, Y162YH, P176Q, K200R, Q228H, D250E, I251V, K259KR, S272P K9KR, T11V, R20K, S107T, I108V, E122EK, A134S, V135VAIT, V167VI, L180I, G195D, C232Y, L244I, R281K 
052009_CNA 052009_CNART None None  I181V L21I, K22R, T27S, K35R, K64R, K66R, K102E, K104R, E122P, E169D, I179A, K200R, G211D, L212M, D218E, Q228K, D250E, I251V, Y271F, S272P, L279I, E304Q, S311E, Y317S, E322G, E324P, I329V, G334A, H335N, E344G, I348T I8V, T11K, K16R, R20K, E32L, Y56F, I90V, S107T, I108V, I118V, H121D, A134S, M138I, T163S, R165G, Q166K, P176N, L180I, I189V, T194S, G195D, E207Q, C232Y, T237K, L244I, Q248E, A268S, I270L, Q320R, K323V, S332N, Q333L, E345N 
077007_CNA 077007_CNART None None   I5V, V10I, T11TM, K22R, K64R, K104R, E122D, M138A, Y162F, P176Q, K200R, F227Y, Q248K, D250E, I251V, S272P, K277R, I329V, G334D, H335N, I341IV, E344G V2VI, R20K, S107T, I108V, A134S, V135I, V167I, L180I, G195D, C232Y, L244I, M287L, T288A, K307R, Y317H, S332D 
519012_CNB 519012_CNBRT None None   I5L, T11Q, L21I, K22R, T27S, K35R, K64R, K66R, D86E, K102E, K104KR, E122P, D123N, M138A, E169D, I179T, K200KR, G211D, L212M, D218E, K223KR, L246I, K249R, D250E, I251V, Y271F, S272P, K277KR, L279I, R284K, L303M, E304Q I8V, R20K, E32L, P51S, M73MT, I90V, S107T, I108V, H121D, A134S, T163S, Q166K, L168LP, P176E, L180I, I189V, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, I270L, I274IS 
523001_CNA 523001_CNART None None   I5V, T11TIM, K22R, K28R, K104R, M138A, Y162H, P176Q, I179T, K200R, F227Y, Q228R, D250E, I251V, S272P R20K, S107T, I108V, A134S, Q166H, L180I, T194I, G195D, C232Y, L244I, R281K, T288A, Y317H 
542001_CNA 542001_CNART None None   P14S, K28R, K35R, T58S, K64R, K68KR, K82R, D86E, D123DGNS, Q126QR, V135T, M138A, A158T, K200R, E207EK, G211D, F227Y, Q228R, D250E, I251V, V254VI, S272P, H278HN V2I, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, K307R 
542012_CNA 542012_CNART None None   K22R, K64R, D86E, K104KR, M138S, P176Q, G211N, D250E, I251V, S272P, K277R T11L, R20K, P51S, S107T, I108V, A134S, Q166K, V167I, L180I, G195D, L196P, C232Y, L244I, R281RK, M287L, Y317H