<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Gottlieb (2011)
Title HIV-2 integrase variation in integrase inhibitor-naïve adults in Senegal, West Africa.
Citation PLoS ONE
SelectedGene IN
SelectedSpecies HIV2
NumIsolates 77
NumPts 39
Host Human


Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
H2A001 11INT002 None    L30Q, S39T, V60T, P119A, I172M, N217S, N222K, E246D, V260I K4R, I18N, I19V, T23I, I28IL, R34K, A41T, N55D, I58L, Y65C, S93T, R215A, N219K, Q224R, H282N 
  11INT001 None    L30Q, S39T, V60T, P119A, I172M, N217S, N222K, E246D, V260I K4R, I18N, I19V, T23I, I28L, R34K, A41T, N55D, I58L, Y65C, S93T, R215A, N219K, Q224R, H282N 
H2A003 11INT003 None    T23S, S39T, V60T, P119A, I172M, Y227F, I250L, D256E, V259I, V260I I18N, I19V, I28L, L30K, I58L, Y65C, V133A, I201V, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  11INT004
Consensus 
Unknown    T23S, S39T, A41X, V60T, P119A, R164K, I172M, Y227F, I250L, D256E, V259I, V260I I18N, I19V, I28L, L30K, I58L, Y65C, V133A, I201V, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  clone: 15 Unknown    T23S, S39T, V60T, P119A, R164RK, I172M, Y227F, I250L, D256E, V259I, V260I I18N, I19V, I28L, L30K, A41AT, I58L, Y65C, V133A, I201V, R215A, N219K, Q224R, L277M, S280SG, P281S, H282N 
  clone: 16 Unknown    T23S, S39T, V60T, P119A, R164RK, I172M, Y227F, I250L, D256DE, V259I, V260I I18N, I19V, I28L, L30K, I58L, Y65C, V133A, I201V, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  11INT005 Unknown    T23S, S39T, V60T, P119A, R164K, I172M, Y227F, I250L, D256E, V259I, V260I I18N, I19V, I28L, L30K, I58L, Y65C, V133A, I201V, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
H2A006 11INT006 Unknown    T23S, S39T, V60T, P119A, S163D, I172V, L213F, S218L, Y227F, V260I, R269K I18N, I19V, I28L, L30K, A41AT, I58L, Y65C, Q96H, E167D, R215A, N219K, Q224R, S280G, P281S, H282N, A286T 
  11INT007 Unknown    T23S, S39T, V60T, P119A, S163D, I172V, L213F, S218L, Y227F, V260I, R269K I18N, I19V, I28L, L30K, I58L, Y65C, Q96H, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
H2A007 11INT008 None    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, D270S, P281PS 
  11INT009
Consensus 
Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, V133A, D270S, P281S 
  clone: 11 Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, V133VA, D270S, P281PS 
  clone: 12 Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, V133VA, D270S, P281PS 
  11INT010
Consensus 
Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, V133A, D270S, P281S 
  clone: 13 Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, V133VA, D270S, P281PS 
  clone: 14 Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, D270S, P281S 
  11INT011 Unknown    L30Q, S39T, P119A, S163N, I172V, E246D I18N, I58V, Y65C, Q96QH, V133VA, D270S, P281PS 
H2A009 11INT012 None   G140R T23S, V32I, S39T, M63I, P119A, W132*, G134S, S163D, I172V, T206A, F220L, Y227F, W243*, E246D, V259I, D270E I18N, G27R, L30K, A41V, G47E, G52R, I58L, Y65C, G82K, G118S, M128I, E167D, R215A, N219K, K221Q, G239E, E240D, T255A, G272R, L277V, S280G, P281S, A286T, R287K 
  11INT013 None    T23S, V32VI, S39T, P119A, S163D, I172V, T206A, F220L, Y227F, E246D, V259I, D270E I18N, L30K, I58L, Y65C, E167D, R215A, N219K, K221Q, Q224R, E240D, T255A, E276D, L277M, S280G, P281S, A286T 
H2A010 11INT014
Consensus 
Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G 
  clone: 3 Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G 
  clone: 4 Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G 
  11INT015
Consensus 
Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, R34K, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G 
  clone: 5 Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, R34RK, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G 
  clone: 6 Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G 
  11INT016 Unknown    T23S, S39T, V60T, P119A, I172M, I210V, R215S, F220L, Y227F, V260I I18N, L30K, R34K, N55D, I58L, Y65C, S93T, Q214H, N219K, Q224R, L277V, S280G, R287K 
H2A014 11INT017 Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172MV, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
  11INT018
Consensus 
Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172V, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
  clone: 19 Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172V, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
  clone: 20 Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172V, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
  11INT019
Consensus 
Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172V, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, G70GR, W132W*, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
  clone: 11 Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172V, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, G70GR, W132W*, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
  clone: 12 Unknown    T23S, L30T, V32I, S39T, A41N, P119A, S163N, I172V, T206A, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, V60I, Y65C, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
H2A020 11INT020 Unknown    L2I, T23S, S39T, V60T, P119A, V133T, R164K, T206A, S218L, F220L, Y227F, E246D I18N, L30K, I58L, Y65C, I201V, Q214H, R215A, N219K, Q224R, S280G, P281S 
  11INT021 Unknown    L2I, T23S, S39T, V60T, P119A, R164K, T206A, S218L, F220L, Y227F, E246D I18N, I19V, I28L, L30K, I58L, Y65C, G82R, V133A, I201V, Q214H, R215A, N219K, Q224R, S280G, P281S 
  11INT022 Unknown    L2I, T23S, S39T, V60T, P119A, R164K, T206A, S218L, F220L, Y227F, E246D, R274RK I18N, I19V, I28L, L30K, I58L, Y65C, V133A, A153S, I201V, Q214H, R215A, N219K, Q224R, S280G, P281S 
  11INT023
Consensus 
Unknown    L2I, I19X, T23S, S39T, V60T, P119A, R164K, T206A, S218L, F220L, Y227F, E246D I18N, I28IL, L30K, I58L, Y65C, V133AT, A153AS, I201V, Q214H, R215A, N219K, Q224R, S280G, P281S 
  clone: 13 Unknown    L2I, T23S, S39T, V60T, P119A, R164K, T206A, S218L, F220L, Y227F, E246D I18N, I19IV, L30K, I58L, Y65C, V133AT, A153AS, I201V, Q214H, R215A, N219K, Q224R, S280G, P281S 
  clone: 14 Unknown    L2I, T23S, S39T, V60T, P119A, R164K, T206A, S218L, F220L, Y227F, E246D I18N, I28L, L30K, I58L, Y65C, V133A, A153S, I201V, Q214H, R215A, N219K, Q224R, S280G, P281S 
H2A021 11INT024 None    T23S, L30Q, V60T, S163N, I172V, V260I K4R, I18N, I19M, I28L, R34K, A41T, I58L, Y65C, P119S, V133I, R215A, N219K, Q224R, H282N 
  11INT025 None    T23S, L30Q, V60T, S163N, I172V, V260I K4R, I18N, I19M, I28L, R34RK, A41T, I58L, Y65C, P119S, V133I, R215A, N219K, Q224R, H282N 
  11INT026 None    T23S, L30Q, S39ST, V60T, S163N, I172V, V260I K4R, I18N, I19M, I28L, R34RK, A41T, I58L, Y65C, P119S, V133I, R215A, N219K, Q224R, H282N 
H2A022 11INT027
Consensus 
None    T23S, S39T, V60T, P119A, I172M, I175V, V180A, R215T, E246D I18N, I19V, K20T, I28L, L30K, A41T, I58V, Y65C, N219K, Q224R, P281S, H282N 
  clone: 87 None    T23S, S39T, V60T, P119A, W131*, W132*, I172M, I175V, V180A, R215T, E246D I18N, I19V, K20T, I28L, L30K, A41T, I58V, Y65C, N219K, Q224R, P281S, H282N 
  clone: 88 None    T23S, S39T, V60T, V88I, P119A, I172M, V180A, R215T, E246D I18N, I19V, K20T, I28L, L30K, A41T, I58V, Y65C, N219K, Q224R, H282N 
  clone: 90 None    T23S, S39T, V60T, P119A, I172IM, I175V, V180A, R215T, E246D I18N, I19V, K20T, I28L, L30K, A41T, I58V, Y65C, N219K, Q224R, P261S, S280G, P281S, H282N 
H2A024 11INT028 None   S138T Y15F, T23S, S39T, V60T, I72V, P119A, S163SN, I172V, T206A, F220L, Y227F, E246D, V259I, R269K I18N, I19V, I28L, L30K, I58L, Y65C, S93T, R215A, N219K, Q224R, L277MV, S280G 
  11INT029
Consensus 
None   S138T Y15F, T23S, S39T, V60T, I72V, P119A, S163X, I172V, T206A, F220L, Y227F, E246D, V259I, R269K I18N, I19V, I28L, L30K, I58L, Y65C, S93T, R215A, N219K, Q224R, L277M, S280G 
  clone: 21 None   S138T Y15F, T23S, S39T, V60T, I72V, P119A, S163DN, I172V, T206A, F220L, Y227F, E246D, V259I, R269K I18N, I19V, I28L, L30K, I58L, Y65C, S93T, R215A, N219K, Q224R, L277M, S280G 
  clone: 22 None   S138T Y15F, T23S, S39T, V60T, I72V, P119A, S163D, I172V, T206A, F220L, Y227F, E246D, V259I, R269K I18N, I19V, I28L, L30K, I58L, Y65C, S93T, R215A, N219K, Q224R, L277M, S280G 
  11INT030 Unknown   S138T Y15F, T23S, S39T, V60T, I72V, P119A, S163D, I172V, T206A, L213F, F220L, Y227F, E246D, V259I, R269K, Y271YH I18N, I19V, I28L, L30K, I58L, Y65C, S93T, R215A, N219K, Q224R, L277M, S280G 
H2A025 11INT031 Unknown    T23S, L30T, V32I, S39T, P119A, S163N, I172V, T206A, F220L, Y227F, E246D I18N, I19V, I28L, A41T, I58L, V60I, Y65C, E167D, R215A, N219K, Q224R, S280G, P281S, H282N 
H2A030 11INT032
Consensus 
Unknown    T23S, L30Q, S39T, A41S, V60T, P119A, I172M, Y227F, E246D, S279N I18N, I19V, I28L, I58L, Y65C, R215A, N219K, Q224R, P281S, H282N 
  clone: 25 Unknown    T23S, L30Q, S39T, A41AS, V60T, P119A, I172IM, Y227F, E246D, S279N I18N, I19V, I28L, I58L, Y65C, R215A, N219K, Q224R, P281S, H282N 
  clone: 26 Unknown    T23S, L30Q, S39T, A41AS, V60T, P119A, I172IM, Y227F, E246D, S279N I18N, I19V, I28L, I58L, Y65C, R215A, N219K, Q224R, P281S, H282N 
H2A031 11INT033 Unknown    T23S, S39T, V60T, I72V, P119A, I172V, E246D, V260I K4R, I18N, I19V, I28L, L30N, A41T, I58L, M63T, Y65C, S93T, R215A, N219K, Q224R, H282N 
H2A033 11INT034 Unknown    Y15F, T23S, S39T, V60T, I72V, P119A, I172V, E246D, V260I I18N, I19V, I28L, L30K, A41T, I58L, Y65C, R215A, N219K, Q224R, H282N 
H2A034 11INT035 None    S17N, T23S, L31I, S39T, A41S, V60T, P119A, F220L, Y227F, V260I I18N, I19V, I28L, L30K, I50M, N55D, I58V, Y65C, Q214H, R215A, N219K, Q224R, L277M, H282N 
  11INT036 Unknown    S17N, T23S, L31I, S39T, V60T, P119A, F220L, Y227F, V260I I18N, I19V, I28L, L30K, I50M, N55D, I58V, Y65C, Q214H, R215A, N219K, Q224R, L277M, S280SG, H282N, G285GS 
  11INT037
Consensus 
Unknown    S17N, T23S, G27X, L31I, S39T, A41S, V60T, P119A, G140X, F220L, Y227F, V260I I18N, I19V, I28L, L30K, I50M, N55D, I58V, Y65C, W132W*, Q214H, R215A, N219K, Q224R, L277M, S280G, H282N 
  clone: 32 Unknown    S17N, T23S, L31I, S39T, A41S, V60T, P119A, F220L, Y227F, V260I I18N, I19V, I28L, L30K, I50M, N55D, I58V, Y65C, Q214H, R215A, N219K, Q224R, L277M, S280G, H282N 
  clone: 34 Unknown   G140GEKR S17N, T23S, L31I, S39T, A41S, V60T, P119A, F220L, Y227F, V260I I18N, I19V, G27GR, I28L, L30K, I50M, N55D, I58V, Y65C, W132W*, Q214H, R215A, N219K, Q224R, L277M, S280G, H282N 
  11INT038
Consensus 
Unknown    S17N, T23S, L31I, S39T, A41X, V60T, P119A, R164X, F220L, Y227F, V260I I18N, I19V, I28L, L30K, I50M, N55D, I58V, Y65C, W132W*, Q214H, R215A, N219K, Q224R, L277M, S280G, H282N 
  clone: 31 Unknown    S17N, T23S, L31I, S39T, V60T, P119A, R164RK, F220L, Y227F, V260I I18N, I19V, I28L, L30K, A41PS, I50M, N55D, I58V, Y65C, W132W*, Q214H, R215A, N219K, Q224R, L277M, S280SG, H282N 
  clone: 32 Unknown    S17N, T23S, L31I, S39T, A41S, V60T, P119A, F220L, Y227F, V260I I18N, I19V, I28L, L30K, I50M, N55D, I58V, Y65C, Q214H, R215A, N219K, Q224R, L277M, S280SG, H282N 
H2A037 11INT039 None   G140R T23S, L30T, S39T, I50T, V60T, I84V, P119A, S163N, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, Y65C, Q214H, R215A, N219K, Q224R, L277V, S280G 
  11INT040 None  R263K  T23S, L30S, S39T, I50T, V60T, P119A, V133T, S163N, F220L, Y227F, E246D K4R, I18N, I19V, G27R, I28L, G47E, I58L, Y65C, G82R, S93T, G118S, Q214H, R215A, N219K, G239K, L277V, S280G, R287K 
  11INT041 None    T23S, L30S, S39T, I50T, V60T, P119A, S163N, F220L, Y227F, E246D K4R, I18N, I19V, I28L, I58L, Y65C, S93T, Q214H, R215A, N219K, Q224R, L277V, S280G 
H2A052 11INT042 None    L2I, T23S, S39T, V60T, P119A, R215T, E246D, V260I K4R, I18N, I19V, I28L, L30N, I50IM, I58L, Y65C, N219K, Q224R, P281S, H282N 
  11INT043
Consensus 
None    L2I, T23S, S39T, V60T, P119A, I172M, R215T, E246D, V260I K4R, I18N, I19V, I28L, L30N, A41T, I58L, Y65C, N219K, Q224R, P281S, H282N 
  clone: 29 None    L2LI, T23S, S39T, V60T, P119A, I172IM, R215T, E246D, V260I K4R, I18N, I19V, I28L, L30N, A41AT, I58L, Y65C, N219K, Q224R, P281S, H282N 
  clone: 30 None    L2I, T23S, S39T, V60T, P119A, I172IM, R215T, E246D, V260I K4R, I18N, I19V, I28L, L30N, A41AT, I58L, Y65C, N219K, Q224R, P281S, H282N 
H2A053 11INT044
Consensus 
None   E125EK T23S, S39T, V60T, M63MI, K71KR, I72V, P119A, G134GS, M154I, R164RK, I172IV, R199RK, T206TA, F220FL, Y227F, E246D, V260VI, G273GR E3EK, E11K, E13EK, I18N, I19V, E21K, G27K, I28L, L30K, A41T, I58L, G59GS, D64N, Y65C, E69EK, G82RE, E85K, S93ST, G118GS, M128MI, W132W*, E136K, G149GE, E152K, E167EK, M203MI, R215A, N219K, Q224R, W235W*, G245GE, G254GE, L277M, S280G, P281S, H282N, E288K 
  clone: 23 None    T23S, S39T, V60T, K71R, I72V, P119A, M154I, I172V, Y227F, E246D, V260I E3K, E11K, E13K, I18N, I19V, E21K, G27K, I28L, L30K, A41T, I58L, D64N, Y65C, G82R, E85K, E136K, E152K, M203I, R215A, N219K, Q224R, G245E, G254E, L277M, S280G, P281S, H282N, E288K 
  clone: 24 None   E125K T23S, S39T, V60T, M63I, I72V, P119A, W132*, G134S, M154I, R164K, R199K, T206A, F220L, Y227F, W235*, E246D, G273R E11K, I18N, I19V, E21K, G27K, I28L, L30K, A41T, I58L, G59S, D64N, Y65C, E69K, G82E, E85K, S93T, G118S, M128I, E136K, G149E, E152K, E167K, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  11INT045 None    T23S, S39T, I50IV, V60T, I72V, Q96N, P119A, I172V, T206A, F220L, Y227F, E246D, V260I I18N, I19V, I28L, L30K, A41T, I58L, Y65C, S93T, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  11INT046 None   R95K, E125K, G140R T23S, S39T, V60T, M63I, G70E, I72V, P119A, W132*, M154I, R164K, R166K, I172V, Y227F, E246D, V260I, D278N E3K, E6K, E11K, E13K, I18N, I19V, E21K, G27K, I28L, L30K, R34K, A41T, E48K, G52K, I58L, G59S, D64N, Y65C, E69K, G82E, E85K, D116N, M128I, E136K, G149E, E152K, E167K, E173K, R215A, N219K, Q224R, G245R, G272E, L277M, S280G, P281S, H282N 
H2A054 11INT047
Consensus 
None   S138T L30Q, S39T, I72V, V133X, S163N, I172M I18N, I19M, T23A, I28L, A41P, Y65C, S93T, I110V, V141I, T171S, Q224R, L234Q, T255A 
  clone: 29 None   S138ST L30Q, S39T, I72V, S163N, I172M I18N, I19M, T23A, I28L, A41P, Y65C, S93T, I110V, V133VI, V141I, T171S, Q224R, L234Q, T255A 
  clone: 30 None   S138ST L30Q, S39T, I72V, S163N, I172M I18N, I19M, T23A, I28L, A41P, Y65C, S93T, I110V, V141I, T171S, Q224R, L234Q, T255A 
  11INT048 None   S138T L30Q, S39T, I72V, N160NT, S163N I18N, I19M, T23A, I28L, Y65C, S93T, I110V, V141I, T171S, Q224R, L234Q, T255A 
H2A055 11INT049
Consensus 
None    S17T, L30Q, S39T, V60T, P119A, I172M, Y227F, D256E, V260I I18N, I19V, T23C, I28L, R34K, A41T, I58V, Y65C, V133I, R215A, N219K, Q224R, H282N 
  clone: 33 None    S17T, L30Q, S39T, V60T, P119A, I172M, Y227F, D256E, V260I I18N, I19V, T23C, I28L, R34K, A41T, I58V, Y65C, V133I, R215A, N219K, Q224R, H282N 
  clone: 34 None    S17T, L30Q, S39T, V60T, P119A, I172M, Y227F, D256E, V260I I18N, I19V, T23C, I28L, R34K, A41T, I58V, Y65C, V133I, R215A, N219K, Q224R, H282N 
  11INT050 None  R263K  S17T, L30Q, S39T, V60T, M63I, P119A, W131*, W132*, G134S, M154I, R166K, Y227F, W243*, D256E, V260I E10K, E13K, I18N, I19V, T23C, G27R, I28L, R34K, A41T, G52R, I58V, Y65C, G82R, G118S, M128I, V133I, G149R, R215A, N219K, Q224R, G239E, H282N 
  11INT051
Consensus 
Unknown    S17T, T23X, G27X, L30X, S39T, V60T, P119A, I172M, Y227F, D256E, V260I I18N, I19V, I28L, R34RK, A41T, G52GR, I58V, Y65C, V133I, R215A, N219K, Q224R, P281S, H282S 
  clone: 34  Unknown    S17T, S39T, V60T, P119A, I172IM, Y227F, D256E, V260I I18N, I19V, T23CS, G27GR, I28L, L30*Q, R34RK, A41T, G52GR, I58V, Y65C, V133I, R215A, N219K, Q224R, H282NS 
  clone: 35 Unknown    S17T, L30Q, S39T, V60T, P119A, I172IM, Y227F, D256E, V260I I18N, I19V, T23C, I28L, R34K, A41T, I58V, Y65C, V133I, R215A, N219K, Q224R, P281PS, H282N 
H2A056 11INT052
Consensus 
Unknown    T23S, I50L, V60T, P119A, T171X, V180X, I201X, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167D, I172L, A197S, Q214H, R215A, N219K, Q224R, S280G, P281S, H282N 
  clone: 37 Unknown    T23S, I50L, V60T, P119A, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167D, I172L, V180AT, A197S, Q214H, R215A, N219K, Q224R, S280G, P281S, H282N 
  clone: 38 Unknown    T23S, I50L, V60T, P119A, I201IL, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167D, T171TS, I172L, V180T, A197S, Q214H, R215A, N219K, Q224R, S280G, P281S, H282N 
H2A057 11INT053 None   G140K T23S, S39T, M63I, P119A, K127R, W131*, W132*, I172V, T206A, F220L, Y227F, E246D I18N, I19V, G27R, L30K, A41T, G52R, I58L, V60I, Y65C, E167D, R215A, N219K, K221Q, G239R, T255A, L277V, P281S 
  11INT054
Consensus 
Unknown    T23S, S39T, P119A, V133X, I172V, D193X, T206A, F220L, Y227F, E246D, R269K I18N, I19V, L30K, A41T, I58L, V60I, Y65C, E167D, R215A, N219K, K221Q, Q224R, T255A, L277V, S280G, P281S 
  clone: 37 Unknown    T23S, S39T, P119A, I172V, T206A, F220L, Y227F, E246D, R269K I18N, I19V, L30K, A41T, I58L, V60I, Y65C, V133VI, E167D, R215A, N219K, K221Q, Q224R, T255A, L277LMV, S280G, P281S 
  clone: 38 Unknown    T23S, S39T, P119A, I172V, T206A, F220L, Y227F, E246D, R269K I18N, I19V, L30K, A41T, I58L, V60I, Y65C, E167D, D193DN, R215A, N219K, K221Q, Q224R, T255A, L277LV, S280G, P281S 
H2A059 11INT055 None   G140R L30Q, S39T, M63I, I72V, W132*, G134S, S163N, I172V, G254R I18N, I19V, G27R, I58L, Y65C, G70R, G82R, P119S, M128I, G192E, P281S 
  11INT056
Consensus 
Unknown    L30Q, N38X, S39T, I72V, I172V, I210X I18N, I19V, I58L, Y65C, P119S, P281S 
  clone: 39 Unknown    L30Q, S39T, I72V, I172V I18N, I19V, I58L, Y65C, P119S, P281S 
  clone: 40 Unknown    L30Q, N38NS, S39T, I72V, I172V, I210IV I18N, I19V, I58L, Y65C, P119S, P281S 
H2A060 11INT057 None   S138T K4N, S17G, T23V, L30Q, H51Q, V60T, P119A, S163D, I172V, I175V, V180A, T206A, L213F, S218L, E246D, D256E, V260I, D270H I18N, I19V, H24Y, G27A, R34K, A41D, Q42K, I58L, Y65C, S93T, E125D, V129A, A153S, E167D, N170V, T171S, I201V, R215A, N219K, Q224R, R274G, Q275K, S279C, P281A, H282D, L283M, G285D, A286T, E288Q 
  11INT058
Consensus 
None   S138T K4N, S17G, T23V, H24X, L30Q, N38X, H51Q, V60T, I72V, P119A, E125X, V133X, S163D, I172V, I175V, V180A, T206A, L213F, S218L, E246D, D256E, V260I, D270H I18N, I19V, G27A, R34K, A41D, Q42K, I58L, Y65C, S93T, V129A, A153S, E167D, N170V, T171S, I201V, R215A, N219K, Q224R, V251I, R274G, Q275K, S279C, P281A, H282D, L283M, G285D, A286T, E288Q 
  clone: 41 None   S138T K4N, S17G, T23V, L30Q, H51Q, V60T, I72V, P119A, S163D, I172V, I175V, V180A, T206A, L213F, S218L, E246D, D256E, V260I, D270H I18N, I19V, H24HY, G27A, R34K, A41D, Q42K, I58L, Y65C, S93T, E125D, V129A, V133VI, A153S, E167D, N170V, T171S, I201V, R215A, N219K, Q224R, R274G, Q275K, S279C, P281A, H282D, L283M, G285D, A286T, E288Q 
  clone: 42 None   S138T K4N, S17G, T23V, L30Q, N38NS, H51Q, V60T, I72V, P119A, S163D, I172V, I175V, V180A, T206A, L213F, S218L, E246D, D256E, V260I, D270H I18N, I19V, H24Y, G27A, R34K, A41D, Q42K, I58L, Y65C, S93T, E125DN, V129A, A153S, E167D, N170V, T171S, I201V, R215A, N219K, Q224R, V251VI, R274G, Q275K, S279C, P281A, H282D, L283M, G285D, A286T, E288Q 
H2A061 11INT059
Consensus 
None    T23S, S39T, V60T, I72V, P119A, I172V, R215T, N222K, Y227F, E246D, V260VI, S279N I18N, L30K, R34K, A41P, N55D, I58V, Y65C, S93T, E167D, N219K, K221Q, Q224R, S280G, P281S 
  clone: 51 None    T23S, S39T, V60T, I72V, P119A, I172V, R215T, N222K, Y227F, E246D, S279N I18N, L30K, R34K, A41P, N55D, I58V, Y65C, S93T, E167D, N219K, K221Q, Q224R, S280G, P281S 
  clone: 52 None    T23S, S39T, V60T, I72V, P119A, I172V, R215T, N222K, Y227F, E246D, V260VI, S279SN I18N, L30K, R34K, A41P, N55D, I58V, Y65C, S93T, E167D, N219K, K221Q, Q224R, S280G, P281S, A286AT 
  11INT060
Consensus 
None    T23S, S39T, V60T, I72V, A80X, P119A, S163X, T171X, I172V, R215T, N222K, Y227F, E246D, V260VI, S279N E6ED, A8AV, I18N, L30K, R34K, A41P, N55D, I58V, Y65C, S93T, E167ED, N219K, K221Q, Q224R, L277M, S280G, P281S, A286T 
  clone: 43 None    T23S, S39T, V60T, I72V, P119A, I172V, R215T, N222K, Y227F, E246D, V260I, S279SN E6D, A8V, I18N, L30K, R34K, A41P, N55D, I58V, Y65C, S93T, E167D, T171TP, N219K, K221Q, Q224R, S280G, P281S, A286T 
  clone: 44 None    T23S, S39T, V60T, I72V, P119A, S163SN, I172V, R215T, N222K, Y227F, E246ED, S279SN I18N, L30K, R34K, A41P, N55D, I58V, Y65C, A80EGV, S93T, E167ED, N219K, K221Q, Q224R, L277LM, S280G, P281S, A286AT 
H2A062 11INT061
Consensus 
None    T23S, I50T, V60T, P119A, I172V, N219R, Y227F, E246D, R262K, R269K I18N, I28L, L30K, R34K, A41P, I58L, Y65C, R215A, Q224R, S280G, P281S, H282N 
  clone: 53 None    T23S, I50T, V60T, P119A, I172V, N219R, Y227F, E246D, R262K, R269K I18N, I28L, L30K, R34K, A41P, I58L, Y65C, R215A, Q224R, S280G, P281S, H282N 
  clone: 54 None    T23S, I50T, V60T, P119A, I172V, N219R, Y227F, E246D, R262K, R269K I18N, I28L, L30K, R34K, A41P, I58L, Y65C, S93ST, R215A, Q224R, S280G, P281S, H282N 
  11INT062
Consensus 
None    T23S, I50T, V60T, I72IV, P119A, E125X, I172V, V180VA, N219R, Y227F, E246D, R262K, R269K I18N, I28L, L30K, R34K, A41P, I58L, Y65C, E167D, R215A, Q224R, S280G, P281S, H282N 
  clone: 25 None    T23S, I50T, V60T, P119A, I172V, N219R, Y227F, E246D, R262K, R269K I18N, I28L, L30K, R34K, A41P, I58L, Y65C, R215A, Q224R, S280G, P281S, H282N 
  clone: 26 None   E125EK T23S, I50T, V60T, I72IV, P119A, I172V, V180VA, N219R, Y227F, E246D, R262K, R269RK I18N, I28L, L30K, R34K, A41P, I58L, Y65C, E167ED, R215A, Q224R, S280G, P281S, H282N 
H2A063 11INT063
Consensus 
None    T23S, S39T, V60T, P119A, Q124QR, I172IM, T206A, I210V, F220L, Y227F, E246D, V259I, V260I I18N, I19IV, I28L, L30K, A41T, I58IL, Y65C, V133I, I201IV, R215A, N219TK, Q224R, L277MV, S280G, P281S, H282N 
  clone: 21 None    T23S, S39T, V60T, P119A, T206A, I210V, F220L, Y227F, E246D, V259I, V260I I18N, I28L, L30K, A41T, I58L, Y65C, V133I, I201V, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  clone: 22 None    T23S, S39T, V60T, P119A, Q124R, I172M, T206A, I210V, N219T, F220L, Y227F, E246D, V259I, V260I I18N, I19V, I28L, L30K, A41T, Y65C, V133I, R215A, Q224R, L277V, S280G, P281S, H282N, A286T 
H2A064 11INT064 None    T23S, S39T, V60T, P119A, I172M, R215T, F220L, I250L I18N, I19V, K20Q, I28L, L30K, I58V, Y65C, Q214H, N219K, Q224R, L234R, K236Q, L277M, S280G, P281T, H282N 
  11INT065
Consensus 
None    T23S, S39T, V60T, P119A, I172M, R215X, F220L, I250L I18N, I19V, K20Q, I28L, L30K, I58V, Y65C, V180T, I201V, Q214H, N219K, Q224R, L234R, K236Q, L277M, S280G, P281T, H282N 
  clone: 23 None    T23S, S39T, V60T, P119A, I172M, F220L, I250L I18N, I19V, K20Q, I28L, L30K, I58V, Y65C, V180VAIT, I201V, Q214H, R215A, N219K, Q224R, L234R, K236Q, L277M, S280G, P281T, H282N 
  clone: 24 None    T23S, S39T, V60T, P119A, I172M, F220L, I250L I18N, I19V, K20Q, I28L, L30K, I58V, Y65C, V180VAIT, I201V, Q214H, R215AT, N219K, Q224R, L234R, K236Q, L277M, S280G, P281T, H282N 
H2A065 11INT066 None    T23S, S39T, V60T, Q96N, P119A, I172M, Y227F, E246D, V259I I18N, I28L, L30K, A41T, I58L, Y65C, R215A, N219K, Q224R, H282N 
H2A066 11INT067 None    T23S, S39T, V60T, I72V, P119A, I172V, V180I, T206A, F220L, Y227F, E246D, V259I, V260I I18N, I28L, L30K, A41P, I58L, Y65C, R215A, N219K, Q224R, T255S, L277M, S280G, H282N 
H2A068 11INT068
Consensus 
None   S138T, G140E S17T, L30T, S39T, V60T, P119A, W132*, I172V, F220L, N222K, Y227F, I250L, V260I I18N, I19V, T23C, G27R, I28L, G52K, Y65C, G82K, G118S, R215A, N219K, K221Q, G239R, S280G, P281S 
  clone: 63 None   S138T, G140E S17T, L30T, S39T, V60T, P119A, W132*, I172V, F220L, N222K, Y227F, I250L, V260I I18N, I19V, T23C, G27R, I28L, G52K, Y65C, G82K, G118S, R215A, N219K, K221Q, G239R, S280G, P281S 
  clone: 64 None   S138T, G140E S17T, L30T, S39T, V60T, P119A, W132*, I172V, F220L, N222K, Y227F, I250L, V260I I18N, I19V, T23C, G27R, I28L, G52K, Y65C, G82K, G118S, R215A, N219K, K221Q, G239R, S280G, P281S 
H2A071 11INT069
Consensus 
None    T23S, S39T, V60T, P119A, I172V, F212X, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167D, Q214H, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  clone: 67 None    T23S, S39T, V60T, P119A, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, Q214H, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  clone: 68 None    T23S, S39T, V60T, P119A, I172V, F212FY, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167ED, Q214H, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  11INT070
Consensus 
None    T23S, S39T, V60T, P119X, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167ED, Q214H, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  clone: 36 None    T23S, S39T, V60T, P119A, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167ED, Q214H, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
  clone: 37 None    T23S, S39T, V60T, P119AT, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41P, N55D, I58L, Y65C, E167D, Q214H, R215A, N219K, Q224R, L277M, S280G, P281S, H282N 
H2A072 11INT071
Consensus 
None   S138T E11D, S17G, T23V, L30Q, V60T, P119A, S163D, I172V, I175V, R215T, S218L, D256E I18N, E21D, A41D, Q42K, I58V, Y65C, S93T, E125D, E167D, N170V, T171S, V180T, I201V, N217K, N219K, K221Q, V251I, D270Q, R274G, Q275K, E276D, S279C, P281A, H282D, L283V, G285D, A286T 
  clone: 69 None   S138T S17G, T23V, L30Q, V60T, P119A, S163D, I172V, I175V, R215T, S218L, D256E I18N, E21D, A41D, Q42K, I58V, Y65C, S93T, E125D, E167D, N170V, T171S, V180T, I201V, N217K, N219K, K221Q, V251I, D270Q, R274G, Q275K, E276D, S279C, P281A, H282D, L283V, G285D, A286T 
  clone: 70 None   S138T E11D, S17G, T23V, L30Q, V60T, P119A, S163D, I172V, I175V, R215T, S218L, D256E I18N, E21D, A41D, Q42K, I58V, Y65C, S93T, E125D, E167D, N170V, T171S, V180T, I201V, N217K, N219K, K221Q, V251I, D270Q, R274G, Q275K, S279C, P281A, H282D, L283V, G285D, A286T 
H2A074 11INT072 None    S39T, V60T, P119A, V180A, R215S, E246D I18N, T23A, I28L, L30K, A41T, N55D, I58L, Y65C, E167D, I172L, L200F, N219K, Q224R, S280G, P281T, H282N 
H2A075 11INT073
Consensus 
None    L2I, T23S, L30Q, S39T, V60T, I72V, P119A, I172V, N222K, E246D I18N, I19V, I28L, A41P, I58L, Y65C, S93T, H156L, R215A, N219K, Q224R, L277M, S280G, G285S 
  clone: 32 None    L2I, T23S, L30Q, S39T, V60T, I72V, P119A, I172V, N222K, E246D I18N, I19V, I28L, A41P, I58L, Y65C, S93T, H156L, R215A, N219K, Q224R, L277M, S280G, G285GS 
  clone: 33 None    L2I, T23S, L30Q, S39T, V60T, I72V, P119A, I172V, N222K, E246D I18N, I19V, I28L, A41P, I58L, Y65C, S93T, H156L, R215A, N219K, Q224R, L277M, S280G, G285GS 
  11INT074
Consensus 
None    L2I, T23S, L30Q, S39T, V60T, I72V, P119A, S163SN, I172V, N222K, E246D I18N, I19V, I28L, A41P, I58L, Y65C, S93T, V133A, H156L, R215A, N219K, Q224R, L277M, S280G, G285S 
  clone: 40 None    L2I, T23S, L30Q, S39T, V60T, I72V, P119A, I172V, N222K, E246D I18N, I19V, I28L, A41P, I58L, Y65C, S93T, V133VA, H156L, R215A, N219K, Q224R, L277M, S280G, H282HN, G285GS 
  clone: 41 None    L2I, T23S, L30Q, S39T, V60T, I72V, P119A, S163N, I172V, N222K, E246D I18N, I19V, I28L, A41P, I58L, Y65C, S93T, H156L, R215A, N219K, Q224R, L277M, S280G, G285S 
H2A076 11INT075
Consensus 
Unknown    T23S, S39T, V60T, I72V, P119A, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41T, N55D, I58L, Y65C, S93T, E167D, Q214H, R215A, N219K, Q224R, L277V, S280G, P281S, H282N 
  clone: 42 Unknown    T23S, S39T, V60T, I72V, P119A, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41T, N55D, I58L, Y65C, S93ST, E167D, Q214H, R215A, N219K, Q224R, L277V, S280G, P281S, H282N 
  clone: 43 Unknown    T23S, S39T, V60T, I72V, P119A, I172V, F220L, Y227F, E246D, V260I I18N, I28L, L30K, A41T, N55D, I58L, Y65C, S93ST, E167D, Q214H, R215A, N219K, Q224R, L277V, S280G, P281S, H282N 
H2A077 11INT076 Unknown   S138T T23S, I28IV, S39T, V60T, I72V, P119A, M154MI, I172V, T206A, F220L, N222NK, Y227F, E246D, R269K I18N, I19IV, L30N, A41P, I58L, Y65C, S93T, E152EQ, A197S, R215A, N219K, K221Q, Q224R, T255S, S280G, P281S, H282HN 
H2A080 11INT077 Unknown    T23S, S39T, V60T, P119A, I172V, R215T, S218L, F220L, Y227F, E246D, R269K I18N, I19V, I28L, L30K, A41T, I50M, I58L, Y65C, Q214H, N219K, Q224R, L277M, S280G, P281S, H282N