Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Jallow (2009)
Title Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants.
Citation J Clin Microbiol
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 21
NumPts 9
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Pat1 TTT9.1 None None   M11T, K28R, P126Q, H162Y, R200K, H228Q, I251V, R307K, E334D, I341V, E344G, V357I, K388X I10V, H121D, E122K, S134A, K176P, L270I, I365V, I397T 
  TTT9.2 AZT, 3TC None  A101AP, L188LF M11T, K28R, K43KR, P126Q, H162Y, R200K, H228Q, I251V I10V, H121D, E122EK, S134A, V167VI, K176P 
Pat11 TTT18.1 None None   K64R, P126Q, H162F, K176Q, G211D, H228R, I251V, E291D, E334D, E344G V5I, Q166H, V167I, L270I, M287L, I365V, I397T, G431K 
  TTT18.2 AZT, 3TC None M184V  K64R, P126Q, H162F, K176Q, G211D, H228R, I251V, E291D, E334D, E344G, V357I V5I, Q166H, V167I, A174V, L270I, M287L, E345D, I365V, I397T, G431K 
  TTT18.3 AZT, 3TC None M184V  K64R, P126Q, H162F, K176Q, G211D, H228R, I251V, E291D, E334D, E344G, V357I V5I, Q166H, V167I, L270I, M287L, L289P, E345D, I365V, I397T, G431K 
Pat12 ARV30.1 None None   M11T, K43R, P126Q, H162Y, K176X, I180L, H228Q, I251V, R307K, E334D, E344G, E396D V5I, M73MI, R104K, V135I, V167I, Y227F, L270I, R281RS, H317C, Q330L, I365V, I397T 
  ARV30.2 AZT, 3TC None   M11T, K28X, K43R, P126Q, H162Y, I180L, R200RK, H228Q, I251V, K286KN, R307K, E334D, E344G, E396D V5I, W71W*, R104K, V135I, V167I, K176P, Y227F, L270I, H317C, Q330L, I365V, I397IT, R424RK, A426V 
Pat2 TTT10.1 None None   M11T, T27S, P126Q, V135T, A138S, I180L, G211S, H228Q, I251IV, R307K, E334D, E344G, V357VI, E396D V5I, I10V, V167I, K176P, Y227F, L270I, I365V, R385RG, I397T, G431K 
  TTT10.2 AZT, 3TC None   M11T, T27S, P126Q, V135T, A138S, I180L, M184X, G211S, H228Q, I251V, R307K, E334D, E344G, V372VI, E396D V5I, I10V, V167I, K176P, Y227F, L270I, L349LV, I365IV, R366RK, L367LV, Q373Q*, I397T, G431K 
  TTT10.3 AZT, 3TC None M184V  M11T, T27S, P126Q, V135T, A138S, I180X, G211S, H228Q, K243KR, I251V V5I, I10V, V167I, K176P, Y227F 
  TTT10.4 AZT, 3TC None M184V  M11T, K20R, T27S, P126Q, V135T, A138S, I180L, G211S, H228Q, I251V, R307K, E334D, E344G, E396D V5I, I10V, E139G, V167I, K176P, Y227F, L270I, I365V, I397T, G431K 
  TTT10.5 AZT, 3TC None M184V  M11T, T27S, P126Q, V135T, A138S, I180L, G211S, H228Q, I251V, R307K, E334D, E344G, E396D V5I, I10V, V167I, K176P, Y227F, L270I, I365V, I397T, G431K 
  TTT10.6 AZT, 3TC None   M11T, T27S, P126Q, V135T, A138S, I180L, G211S, H228Q, I251V, R307K, E334D, E344G, E396D V5I, I10V, V167I, K176P, Y227F, L270I, I365V, I397T, G431K 
Pat5 TTT13.1 None None   M11T, K43R, T107S, P126Q, H162Y, K176S, H228Q, I251V, L270V, L289I, R307K, E334D, E344G, V372I, E396D, I397V I10V, V167I, H317C, E324D, Q333C, V357M, K358R, I365V, A426V, G431K 
Pat6 TTT14.1 None None   T27S, K28R, K82KR, V111I, P126Q, H162X, K173R, G211GS I10V, R104RK, M164T, V167I, K176P 
  TTT14.2 AZT, 3TC None   T27S, K28R, V111I, P126Q, H162Y, K173R, G211S, K249R, I251V, R307K, E321Q, E334D, E344G, V357I, E396D, N404D I10V, M164T, V167I, K176P, L270I, M287L, Q294K, E345D, I365V, I397T 
Pat7 TTT15.1 None None  I181V M11T, K43R, T107S, P126Q, H162Y, I180L, H228Q, I251V, R307K, E334D, E344G, E396D I8L, I10V, R104K, S134P, V135I, V167I, K176P, R200T, L270I, H317C, I365V, I397T, A426V, G431K 
  TTT15.2 AZT, 3TC None  I181V M11T, K35R, T107S, P126Q, H162Y, I180L, H228Q, I251V, R307K, E334D, E344G, E396D I8L, I10V, R104K, S134P, V135I, V167I, K176P, L270I, H317C, I365V, I397T, A426V, G431K 
Pat8 TTT16.1 None None   M11T, K28R, D86E, D123E, P126Q, H162Y, R200Q, H228R, I251V, E334D, I341IV, E344G, V357VI V5VI, I10V, H121W, S134A, K176P, L270I, K286R, I365V, D413E 
Pat9 TTT17.1 None None   M11T, F87L, P126Q, H162Y, K173R, I180L, H228K, R307K, E334D, E344G, N359H, A369S, E396D V2I, I8V, I10V, R22K, I90V, T163M, V167I, K176P, Y227F, L270I, H317C, I365V, R366K, D413E, A426V, G431K 
  TTT17.2 AZT, 3TC None   K64R, P126Q, H162Y, K176Q, G211D, H228R, I251V, E291D, R307K, E334D, E344G V5I, Q166H, V167I, L196I, L205I, L209V, K249I, L270I, M287L, K347N, I365V, I397T, G431K