<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Jallow (2009)
Title Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants.
Citation J Clin Microbiol
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 21
NumPts 9
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Pat1 TTT9.1 None None   I5V, K22R, K28R, K104R, M138A, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, K388X R20K, S107T, I108V, H121D, E122K, L180I, G195D, C232Y, L244I, Y317H, S332D, ~346. 
  TTT9.2 AZT, 3TC None  A101AP, L188LF I5V, K22R, K28R, K43KR, K104R, M138A, F227Y, D250E, I251V R20K, S107T, I108V, H121D, E122EK, V167VI, L180I, G195D, C232Y, L244I 
Pat11 TTT18.1 None None   V10I, T11M, K22R, K64R, K104R, M138A, Y162F, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, I357V, E413D R20K, S107T, I108V, A134S, Q166H, V167I, L180I, G195D, C232Y, L244I, M287L, K307R, Y317H, S332D, ~346., T426A, G431K 
  TTT18.2 AZT, 3TC None M184V  V10I, T11M, K22R, K64R, K104R, M138A, Y162F, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, E413D R20K, S107T, I108V, A134S, Q166H, V167I, A174V, L180I, G195D, C232Y, L244I, M287L, K307R, Y317H, S332D, E345D, ~346., T426A, G431K 
  TTT18.3 AZT, 3TC None M184V  V10I, T11M, K22R, K64R, K104R, M138A, Y162F, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, E413D R20K, S107T, I108V, A134S, Q166H, V167I, L180I, G195D, C232Y, L244I, M287L, L289P, K307R, Y317H, S332D, E345D, ~346., T426A, G431K 
Pat12 ARV30.1 None None   V10I, K22R, K43R, M138A, P176X, K200R, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, M73MI, S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, R281RS, Y317C, Q330L, S332D, ~346. 
  ARV30.2 AZT, 3TC None   V10I, K22R, K28X, K43R, M138A, K200KR, D250E, I251V, S272P, K286KN, I329V, G334D, H335N, E344G, I357V, E396D, T397TI, E413D R20K, W71W*, S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, Y317C, Q330L, S332D, ~346., R424RK, T426V 
Pat2 TTT10.1 None None   K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251IV, S272P, I329V, G334D, H335N, E344G, I357IV, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, ~346., R385RG, T426A, G431K 
  TTT10.2 AZT, 3TC None   K22R, T27S, K104R, V135T, M138S, Y162H, M184X, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, V365VI, V372VI, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, ~346., L349LV, R366RK, L367LV, Q373Q*, T426A, G431K 
  TTT10.3 AZT, 3TC None M184V  K22R, T27S, K104R, V135T, M138S, Y162H, L180X, K200R, G211S, K243KR, D250E, I251V R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I 
  TTT10.4 AZT, 3TC None M184V  K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D S107T, I108V, A134S, E139G, V167I, G195D, C232Y, L244I, Y317H, S332D, ~346., T426A, G431K 
  TTT10.5 AZT, 3TC None M184V  K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, ~346., T426A, G431K 
  TTT10.6 AZT, 3TC None   K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, ~346., T426A, G431K 
Pat5 TTT13.1 None None   I5V, K22R, K43R, K104R, M138A, P176S, K200R, F227Y, D250E, I251V, I270V, S272P, L289I, I329V, G334D, H335N, E344G, V372I, E396D, T397V, E413D R20K, I108V, A134S, V167I, L180I, G195D, C232Y, L244I, Y317C, E324D, S332D, Q333C, ~346., I357M, K358R, T426V, G431K 
Pat6 TTT14.1 None None   I5V, T11M, K22R, T27S, K28R, K82KR, K104KR, V111I, M138A, Y162X, K173R, K200R, G211GS, F227Y, Q228H R20K, S107T, I108V, A134S, M164T, V167I, L180I, G195D, C232Y, L244I 
  TTT14.2 AZT, 3TC None   I5V, T11M, K22R, T27S, K28R, K104R, V111I, M138A, K173R, K200R, G211S, F227Y, Q228H, K249R, D250E, I251V, S272P, E321Q, I329V, G334D, H335N, E344G, E396D, N404D, E413D R20K, S107T, I108V, A134S, M164T, V167I, L180I, G195D, C232Y, L244I, M287L, Q294K, Y317H, S332D, E345D, ~346., T426A 
Pat7 TTT15.1 None None  I181V I5V, K22R, K43R, M138A, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D I8L, R20K, I108V, A134P, V135I, V167I, G195D, K200T, C232Y, L244I, Y317C, S332D, ~346., T426V, G431K 
  TTT15.2 AZT, 3TC None  I181V I5V, K22R, K35R, M138A, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D I8L, R20K, I108V, A134P, V135I, V167I, G195D, C232Y, L244I, Y317C, S332D, ~346., T426V, G431K 
Pat8 TTT16.1 None None   I5IV, K22R, K28R, D86E, K104R, D123E, M138A, K200Q, F227Y, Q228R, D250E, I251V, S272P, I329V, G334D, H335N, I341IV, E344G, I357IV, T397I R20K, S107T, I108V, H121W, L180I, G195D, C232Y, L244I, K286R, K307R, Y317H, S332D, ~346. 
Pat9 TTT17.1 None None   I5V, F87L, K104R, M138A, K173R, K200R, Q228K, D250E, S272P, I329V, G334D, H335N, E344G, I357V, N359H, A369S, E396D, T397I V2I, I8V, R20K, I90V, S107T, I108V, A134S, T163M, V167I, G195D, C232Y, L244I, Y317C, S332D, ~346., R366K, T426V, G431K 
  TTT17.2 AZT, 3TC None   V10I, T11M, K22R, K64R, K104R, M138A, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, I357V, E413D R20K, S107T, I108V, A134S, Q166H, V167I, L180I, G195D, L196I, L205I, L209V, C232Y, L244I, K249I, M287L, Y317H, S332D, ~346., K347N, T426A, G431K