<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Jallow (2009)
Title Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants.
Citation J Clin Microbiol
SelectedGene RT
SelectedSpecies HIV2
NumIsolates 21
NumPts 9
Host Human

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ARV30 Pat12 None None   V10I, K22R, K43R, M138A, P176PS, K200R, D250E, I251V, S272P, I329V, Q330L, G334D, H335N, E344G, I357V, E396D, E413D R20K, M73MI, S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, R281RS, Y317C, S332D 
   AZT, 3TC None   V10I, K22R, K43R, M138A, K200KR, D250E, I251V, S272P, K286KN, I329V, Q330L, G334D, H335N, E344G, I357V, E396D, T397TI, E413D R20K, K28KIRT, W71W*, S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, Y317C, S332D, R424RK, T426V 
TTT10 Pat2 None None   K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251IV, S272P, I329V, G334D, H335N, E344G, I357IV, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, R385RG, T426A, G431K 
   AZT, 3TC None M184MIV  K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, V365VI, V372VI, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, L349LV, R366RK, L367LV, Q373Q*, T426A, G431K 
    AZT, 3TC None M184V  K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, K243KR, D250E, I251V R20K, S107T, I108V, A134S, V167I, L180LF, G195D, C232Y, L244I 
    AZT, 3TC None M184V  K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D S107T, I108V, A134S, E139G, V167I, G195D, C232Y, L244I, Y317H, S332D, T426A, G431K 
    AZT, 3TC None M184V  K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, T426A, G431K 
    AZT, 3TC None   K22R, T27S, K104R, V135T, M138S, Y162H, K200R, G211S, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, T426A, G431K 
TTT13 Pat5 None None   I5V, K22R, K43R, K104R, M138A, P176S, K200R, F227Y, D250E, I251V, I270V, S272P, L289I, I329V, G334D, H335N, E344G, V372I, E396D, T397V, E413D R20K, I108V, A134S, V167I, L180I, G195D, C232Y, L244I, Y317C, E324D, S332D, Q333C, I357M, K358R, T426V, G431K 
TTT14 Pat6 None None   I5V, T11M, K22R, T27S, K28R, K82KR, K104KR, V111I, M138A, Y162YF, K173R, K200R, G211GS, F227Y, Q228H R20K, S107T, I108V, A134S, M164T, V167I, L180I, G195D, C232Y, L244I 
   AZT, 3TC None   I5V, T11M, K22R, T27S, K28R, K104R, V111I, M138A, K173R, K200R, G211S, F227Y, Q228H, K249R, D250E, I251V, S272P, E321Q, I329V, G334D, H335N, E344G, E396D, N404D, E413D R20K, S107T, I108V, A134S, M164T, V167I, L180I, G195D, C232Y, L244I, M287L, Q294K, Y317H, S332D, E345D, T426A 
TTT15 Pat7 None None  I181V I5V, I8L, K22R, K43R, M138A, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, I108V, A134P, V135I, V167I, G195D, K200T, C232Y, L244I, Y317C, S332D, T426V, G431K 
   AZT, 3TC None  I181V I5V, I8L, K22R, K35R, M138A, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, I108V, A134P, V135I, V167I, G195D, C232Y, L244I, Y317C, S332D, T426V, G431K 
TTT16 Pat8 None None   I5IV, K22R, K28R, D86E, K104R, D123E, M138A, K200Q, F227Y, Q228R, D250E, I251V, S272P, I329V, G334D, H335N, I341IV, E344G, I357IV, T397I R20K, S107T, I108V, H121W, L180I, G195D, C232Y, L244I, K286R, K307R, Y317H, S332D 
TTT17 Pat9 None None   I5V, F87L, K104R, M138A, K173R, K200R, Q228K, D250E, S272P, I329V, G334D, H335N, E344G, I357V, N359H, A369S, E396D, T397I V2I, I8V, R20K, I90V, S107T, I108V, A134S, T163M, V167I, G195D, C232Y, L244I, Y317C, S332D, R366K, T426V, G431K 
   AZT, 3TC None   V10I, T11M, K22R, K64R, K104R, M138A, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, I357V, E413D R20K, S107T, I108V, A134S, Q166H, V167I, L180I, G195D, L196I, L205I, L209V, C232Y, L244I, K249I, M287L, Y317H, S332D, K347N, T426A, G431K 
TTT18 Pat11 None None   V10I, T11M, K22R, K64R, K104R, M138A, Y162F, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, I357V, E413D R20K, S107T, I108V, A134S, Q166H, V167I, L180I, G195D, C232Y, L244I, M287L, K307R, Y317H, S332D, T426A, G431K 
   AZT, 3TC None M184V  V10I, T11M, K22R, K64R, K104R, M138A, Y162F, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, E413D R20K, S107T, I108V, A134S, Q166H, V167I, A174V, L180I, G195D, C232Y, L244I, M287L, K307R, Y317H, S332D, E345D, T426A, G431K 
    AZT, 3TC None M184V  V10I, T11M, K22R, K64R, K104R, M138A, Y162F, P176Q, K200R, G211D, F227Y, Q228R, D250E, I251V, S272P, E291D, I329V, G334D, H335N, E344G, E413D R20K, S107T, I108V, A134S, Q166H, V167I, L180I, G195D, C232Y, L244I, M287L, L289P, K307R, Y317H, S332D, E345D, T426A, G431K 
TTT9 Pat1 None None   I5V, K22R, K28R, K104R, M138A, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, K388KIRT R20K, S107T, I108V, H121D, E122K, L180I, G195D, C232Y, L244I, Y317H, S332D 
   AZT, 3TC None  A101AP, L188LF I5V, K22R, K28R, K43KR, K104R, M138A, F227Y, D250E, I251V R20K, S107T, I108V, H121D, E122EK, V167VI, L180I, G195D, C232Y, L244I 

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