Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Sagoe (2012)
Title Distinct patterns of protease gene polymorphisms in human immunodeficiency virus type 1 strains found in drug naive individuals in Ghana.
Citation Direct Genbank Submission
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 15
NumPts 15
Subtype CRF02_AG, CRF06_cpx, G


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
KAF11 KAF11 None None   V35T, E36D, T39L, V60I, V90I, K122E, I135V, S162A, F171Y, K173T, Q174E, D177E, T200A, Q207E, V245E, T286A, V292I, I293V, S322T, D324E, G335D  
KAF121 KAF121 None None   V21I, V35T, E36D, T39K, K43E, V60I, I135V, S162A, M164ML, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248DN, T286A, E291D, V292I, I293V, S322T, I326V, G335D E29EG 
KAF124 KAF124 None None   V35T, E36ED, S68G, K122E, D123E, I135V, A158AS, S162A, K173T, Q174K, D177E, I178L, T200A, Q207E, R211RK, V245N, A272P, K281R, T286A, E291D, S322T, G335D R172RS 
KAF130 KAF130 None None   V35T, T39R, S48E, K49R, I50V, V60I, K122E, D123N, S162C, K173R, Q174K, D177E, T200A, Q207E, R211A, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, I326V  
KAF149 KAF149 None None   P4S, V35T, E36D, T39K, I135K, S162A, K173T, Q174G, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, T286A, E291D, V292I, I293V, P294V, S322T, G335D  
KAF151 KAF151 None None   V35T, T39A, V60I, K122E, I135V, S162A, K173S, D177E, V179I, T200A, I202V, Q207D, R211RK, V245E, T286A, I293V, P294T, E312D, I326V, G335D  
KAF41 KAF41 None None  V108VI, V179VE V21I, V35T, T39E, E40D, V60I, K102E, K122P, E138A, S162A, K173T, Q174K, D177E, I178LM, T200A, Q207G, R211K, V245Q, E248D, D250E, A272P, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, I329V, Q334L, G335D K64KE 
KAF5 KAF5 None None   V35T, E40D, V60I, K122P, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, P243Q, V245Q, L283I, T286A, E291D, I293V, P294T, L295M, L310I, P313PT, S322A  
KAF66 KAF66 None None   V35T, E36D, D121H, K122E, S162A, K173A, Q174K, D177E, I178V, T200A, Q207N, R211K, V245Q, D250E, A272P, Q278H, K281R, T286A, E291D, I293V, E297A, L301M, I326T, I329V, Q334P, G335D D320DANT 
KAF71 KAF71 None None  V108I, V179E V35R, K64R, K122KE, D123E, I135V, S162A, K173T, Q174K, D177E, V189I, T200A, Q207E, V245Q, D250E, V254I, T286A, E291D, V292I, I293V, P294T, L295M, S322T  
KAF72 KAF72 None None   K32R, V35T, V60I, K173R, Q174E, D177E, I178M, T200A, Q207T, R211K, V245Q, E248D, K277R, T286A, E291D, V292I, I293V, E297A, Q334D  
KAF74 KAF74 None None   V35T, E36D, T39M, K102KQ, K122E, I135V, S162A, F171Y, K173T, Q174K, D177E, G196E, T200A, Q207E, E248D, S251R, T286A, E291D, V292I, I293V, P294T, S322A, G335D  
KAF75 KAF75 None None   V35T, E40D, K49R, K122Q, I135V, S162A, E169D, F171Y, K173AT, Q174K, D177E, V179VI, G196E, T200A, Q207E, R211K, V245Q, D250E, V261I, A272P, V276I, T286A, E291D, V292I, I293V, S322T, I326V  
KAF78 KAF78 None None   K20KR, V35T, E36D, T39I, K49KR, V60I, S68T, I135V, E138A, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, R211RK, F214L, L228H, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D  
KAF83 KAF83 None None   K32KR, V35T, E36D, T39M, V60I, A98S, I135V, S162A, D177E, T200A, Q207D, R211K, V245Q, A272P, K275Q, V276VI, K277R, T286A, E291D, I293V, P294T, S322T, G335D